Inflammation II
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Questions and Answers

Which of the following is a component of acute inflammation?

  • Caliber and flow
  • Chronic inflammation
  • Chemotaxis
  • Margination (correct)

    • What is the significance of inflammation in disease?

  • It helps in tissue repair (correct)
  • It causes chronic inflammation
  • It facilitates microbial growth
  • It leads to leukocyte dysfunction

    • What are the cardinal signs of inflammation?

  • Redness, swelling, heat, pain (correct)
  • Dizziness, blurred vision, confusion, weakness
  • Nausea, vomiting, diarrhea, abdominal pain
  • Fever, cough, headache, fatigue

    • Which step of extravasation of leukocytes involves the movement of leukocytes through venule walls?

    <p>Transmigration (D)</p> Signup and view all the answers

    Which adhesion molecules mediate firm adhesion between activated endothelial cells and leukocytes?

    <p>ICAM and VCAM (B)</p> Signup and view all the answers

    Which mediator stimulates endothelial mitosis in the process of angiogenesis?

    <p>VEGF (C)</p> Signup and view all the answers

    Which molecules facilitate the transient interactions between leukocytes and endothelial cells during rolling?

    <p>Selectins (B)</p> Signup and view all the answers

    Which of the following is a characteristic of acute inflammation?

    <p>Presence of neutrophils within the alveolar spaces (B)</p> Signup and view all the answers

    What are the vascular changes that occur during acute inflammation?

    <p>Vasoconstriction followed by dilation of the arteriolar side of the capillary bed (C)</p> Signup and view all the answers

    What is the purpose of inflammation?

    <p>To eliminate the initial cause of injury and remove necrotic debris (C)</p> Signup and view all the answers

    What are the components of the inflammatory response?

    <p>All of the above (D)</p> Signup and view all the answers

    Which molecule triggers a release of intracellular calcium stores in leukocytes?

    <p>IP3 (A)</p> Signup and view all the answers

    Which enzyme metabolizes membrane phospholipids producing arachidonic acid metabolites?

    <p>Phospholipase A2 (C)</p> Signup and view all the answers

    Which protein is responsible for the formation of pseudopods during phagocytosis?

    <p>G protein (A)</p> Signup and view all the answers

    Which protein converts hydrogen peroxide to a very lethal free radical?

    <p>Myeloperoxidase (D)</p> Signup and view all the answers

    Which of the following is a mechanism responsible for increased vascular permeability in acute inflammation?

    <p>Increased blood flow (D)</p> Signup and view all the answers

    What happens when arteriolar hydrostatic pressure increases during acute inflammation?

    <p>Fluid moves from the blood plasma into the interstitial space (D)</p> Signup and view all the answers

    Which type of injury involves endothelial cell death?

    <p>Stimulus-necrosis-apoptosis (B)</p> Signup and view all the answers

    Which response is secondary to adhesion and activation of leukocytes?

    <p>Leukocyte-dependent endothelial injury (D)</p> Signup and view all the answers

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