Inflammation II

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Which of the following is a component of acute inflammation?

Caliber and flow

Chronic inflammation

Chemotaxis

Margination (correct)

What is the significance of inflammation in disease?

It helps in tissue repair (correct)

It causes chronic inflammation

It facilitates microbial growth

It leads to leukocyte dysfunction

What are the cardinal signs of inflammation?

Redness, swelling, heat, pain (correct)

Dizziness, blurred vision, confusion, weakness

Nausea, vomiting, diarrhea, abdominal pain

Fever, cough, headache, fatigue

Which step of extravasation of leukocytes involves the movement of leukocytes through venule walls?

Transmigration Signup and view all the answers

Which adhesion molecules mediate firm adhesion between activated endothelial cells and leukocytes?

ICAM and VCAM Signup and view all the answers

Which mediator stimulates endothelial mitosis in the process of angiogenesis?

VEGF Signup and view all the answers

Which molecules facilitate the transient interactions between leukocytes and endothelial cells during rolling?

Selectins Signup and view all the answers

Which of the following is a characteristic of acute inflammation?

Presence of neutrophils within the alveolar spaces Signup and view all the answers

What are the vascular changes that occur during acute inflammation?

Vasoconstriction followed by dilation of the arteriolar side of the capillary bed Signup and view all the answers

What is the purpose of inflammation?

To eliminate the initial cause of injury and remove necrotic debris Signup and view all the answers

What are the components of the inflammatory response?

All of the above Signup and view all the answers

Which molecule triggers a release of intracellular calcium stores in leukocytes?

IP3 Signup and view all the answers

Which enzyme metabolizes membrane phospholipids producing arachidonic acid metabolites?

Phospholipase A2 Signup and view all the answers

Which protein is responsible for the formation of pseudopods during phagocytosis?

G protein Signup and view all the answers

Which protein converts hydrogen peroxide to a very lethal free radical?

Myeloperoxidase Signup and view all the answers

Which of the following is a mechanism responsible for increased vascular permeability in acute inflammation?

Increased blood flow Signup and view all the answers

What happens when arteriolar hydrostatic pressure increases during acute inflammation?

Fluid moves from the blood plasma into the interstitial space Signup and view all the answers

Which type of injury involves endothelial cell death?

Stimulus-necrosis-apoptosis Signup and view all the answers

Which response is secondary to adhesion and activation of leukocytes?

Leukocyte-dependent endothelial injury Signup and view all the answers