Inflammatio Gingivae

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Questions and Answers

What is the main cell type found in the established lesion?

  • Plasma cells (correct)
  • Fibroblasts
  • Macrophages
  • Neutrophils

Which adhesion molecules are present in the initial lesion?

  • VCAM-1
  • P-selectin
  • ICAM-1 (correct)
  • L-selectin

What is the predominant cell type in the advanced lesion?

  • Macrophages
  • Neutrophils
  • Lymphocytes
  • Plasma cells (correct)

Which type of immunity involves memory and specialized immune response?

<p>Adaptive immunity (C)</p> Signup and view all the answers

Which cells are part of the 'First-line' defense in innate immunity?

<p>Neutrophils and macrophages (B)</p> Signup and view all the answers

Which type of immunity has a rapid response to microbes and limited diversity?

<p>Innate Immunity (D)</p> Signup and view all the answers

Which cells are involved in adaptive immunity and provide memory?

<p>Lymphocytes (B &amp; T) (D)</p> Signup and view all the answers

Which component is associated with humoral immunity?

<p>Antibodies/Cytokines (C)</p> Signup and view all the answers

Which type of immunity is the primary defense against extracellular bacteria and circulating viruses?

<p>Humoral-mediated immunity (C)</p> Signup and view all the answers

What is the primary defense against intracellular pathogens such as viruses, fungi, and intracellular bacteria?

<p>Cell-mediated immunity (C)</p> Signup and view all the answers

Which type of immunity involves B lymphocytes and antibodies circulating in serum?

<p>Humoral-mediated immunity (D)</p> Signup and view all the answers

What is the function of the inflammatory response?

<p>Dilute/wall off damaging microorganisms (D)</p> Signup and view all the answers

What is the function of the GCF (Gingival Crevicular Fluid) in acute inflammation?

<p>Washes non-adherent bacteria out of the crevice (A)</p> Signup and view all the answers

What is the role of macrophages in the inflammatory and immune responses?

<p>Phagocytosis of pathogens (C)</p> Signup and view all the answers

What is the main function of the junctional epithelium in the inflammatory response?

<p>Release cytokines and host-defense peptides (A)</p> Signup and view all the answers

Which cell type in the gingival epithelium is involved in the immune response?

<p>Langerhans’ cells (D)</p> Signup and view all the answers

What serves as a physical barrier to plaque microorganisms in the epithelium?

<p>Epithelial cells being tightly attached to each other (C)</p> Signup and view all the answers

What is the primary effect of saliva on the development of plaque and caries?

<p>Antimicrobial effects supragingivally (A)</p> Signup and view all the answers

Where are the direct effects of saliva not observed in relation to oral health?

<p>Subgingivally (A)</p> Signup and view all the answers

What cells present antigenic material to circulating lymphocytes in the humoral immune response?

<p>Epithelial Langerhans’ cells (C)</p> Signup and view all the answers

Which type of antibody production is thought to be particularly protective in the humoral immune response?

<p>IgG and IgA (B)</p> Signup and view all the answers

What is the primary function of B-lymphocytes in the humoral immune response?

<p>To differentiate into plasma cells that secrete antibody (B)</p> Signup and view all the answers

What is the primary role of T-helper lymphocytes in the cell mediated response?

<p>Phagocytosis (B)</p> Signup and view all the answers

Which type of cells are associated with the immune response in gingivitis?

<p>Th1 cells (B)</p> Signup and view all the answers

In the context of periodontitis, what type of cells are involved in the shift to B cells?

<p>Th2 cells (D)</p> Signup and view all the answers

Which of the following is an example of pro-inflammatory cytokines?

<p>IL-1 (A)</p> Signup and view all the answers

Which of the following is responsible for bone resorption, neutrophil chemotaxis, vascular permeability, and dilation?

<p>PGE-2 (C)</p> Signup and view all the answers

Which of the following mediators is involved in degrading connective tissue and is pro-inflammatory?

<p>Matrix metalloproteinases (B)</p> Signup and view all the answers

What is the primary function of cytokines in the immune system?

<p>Mediate and regulate immunity, inflammation, and hematopoiesis (C)</p> Signup and view all the answers

Which type of cytokine can cause many different effects on the target cell?

<p>Pleiotropic cytokines (D)</p> Signup and view all the answers

Which type of cytokine elicits the same response from their targets as many other cytokines?

<p>Redundant cytokines (C)</p> Signup and view all the answers

Which type of cytokine is capable of blocking the effect of another cytokine?

<p>Antagonistic cytokines (A)</p> Signup and view all the answers

Which pathway produces prostaglandins that can cause vasodilation or vasoconstriction?

<p>COX pathway (B)</p> Signup and view all the answers

Which pathway produces potent chemo-attractants for neutrophils?

<p>LOX pathway (C)</p> Signup and view all the answers

Which products are a potent stimulus of bone resorption?

<p>Prostaglandins PGEs (A)</p> Signup and view all the answers

What is the primary responsibility of Matrix Metalloproteinases (MMPs)?

<p>Degrading extracellular matrix collagen (B)</p> Signup and view all the answers

In which pathological conditions is there an increased expression of MMPs?

<p>Conditions leading to tissue destruction (D)</p> Signup and view all the answers

What role does MMP-8 play as an indicator?

<p>Indicator of disease severity (D)</p> Signup and view all the answers

What is the primary function of Thrombocytes/Platelets?

<p>Initiate the clotting cascade (B)</p> Signup and view all the answers

Which component is found in the Plasma and is important for homeostasis?

<p>Fibrinogen (A)</p> Signup and view all the answers

What is the main function of Erythrocytes/Red Blood Cells (RBCs)?

<p>Transport oxygen and carbon dioxide (D)</p> Signup and view all the answers

What is the lifespan of platelets?

<p>5-9 days (A)</p> Signup and view all the answers

What do platelets release through the cell membrane when activated?

<p>Cytokines (A)</p> Signup and view all the answers

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