Infectious Mononucleosis and EBV Management
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Questions and Answers

What is the primary focus of treatment for infectious mononucleosis?

  • Symptom management (correct)
  • Immediate surgical intervention
  • Long-term antiviral therapy
  • Completely eradicating the virus
  • Which laboratory test is commonly used to confirm EBV infection?

  • Monospot blood test (correct)
  • Throat culture
  • Liver function test
  • Complete blood count (CBC)
  • What should be avoided in individuals recovering from EBV mono due to the risk of splenic rupture?

  • High altitude travel
  • Cold temperature exposure
  • Contact sports (correct)
  • Strenuous exercise
  • Which of the following is a documented complication of EBV infection?

    <p>Splenic rupture</p> Signup and view all the answers

    In what circumstances might antiviral therapy be considered for EBV infection?

    <p>For patients with chronic EBV symptoms</p> Signup and view all the answers

    Study Notes

    Diagnosis and Confirmation of EBV Infection

    • Diagnosis relies on clinical presentation.
    • Monospot blood test is a common, rapid diagnostic tool.
    • Complete blood count (CBC) often shows increased bands, neutrophils, lymphocytes, reactive lymphocytes, and thrombocytopenia.

    Treatment and Management of Infectious Mononucleosis (Mono)

    • Treatment primarily focuses on managing symptoms.
    • Analgesics are used to alleviate fever and muscle pain (myalgias).
    • Short-term oral glucocorticoids might be beneficial for severely enlarged tonsils or airway obstruction concerns.
    • Antivirals are generally unnecessary, as symptoms stem from the immune response rather than viral replication; however they may be considered in cases of chronic EBV.
    • Contact sports should be avoided to prevent splenic rupture, resuming only after splenomegaly resolves (typically within weeks).
    • Fatigue is a common symptom that may persist for 2-6 months.

    Complications of EBV Infection

    • Splenic rupture is a potential complication.
    • EBV infection increases the risk of B-cell lymphomas (Burkitt lymphoma, classical Hodgkin lymphoma) and certain cancers (gastric and nasopharyngeal).
    • Hemolytic anemia, thrombocytopenia, meningitis, myelitis, and Guillain-Barré syndrome are possible complications of EBV and CMV co-infections.
    • Reactivation can occur in immunosuppressed states.

    Cytomegalovirus (CMV) Infection

    • Prior CMV infection leads to latent viral persistence in the body.
    • Latent CMV resides in all solid organs and can reactivate following transplantation and subsequent immunosuppressive therapy.

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    Description

    This quiz covers the diagnosis, treatment, and complications of infectious mononucleosis (Mono) caused by Epstein-Barr virus (EBV). It explores clinical presentation, common diagnostic tools, and management strategies. Learn about the symptoms, complications, and necessary precautions for those affected by EBV.

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