Infectious Diseases Overview
31 Questions
0 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What defines an infectious disease?

  • Microorganisms that utilize a host's resources to reproduce. (correct)
  • Microorganisms that reproduce without a host.
  • Microorganisms that exist in a dormant state within the host.
  • Microorganisms that enhance the host's immune response.
  • Which of the following statements about microorganisms is correct?

  • All microorganisms cause disease.
  • Microorganisms can only reproduce inside the host.
  • Microorganisms are only harmful during specific seasons.
  • Most microorganisms are harmless and do not cause disease. (correct)
  • Which element is essential for defining the term 'host' in the context of infectious disease?

  • It must exclusively eliminate pathogens.
  • It must provide resources for pathogen reproduction. (correct)
  • It must be a microorganism.
  • It must exist in a stable environment.
  • What is the significance of Koch’s postulates in the study of infectious diseases?

    <p>They provide a framework for identifying the causative agents of infectious diseases. (A)</p> Signup and view all the answers

    What aspect of infectious disease transmission is crucial to understand?

    <p>Various methods exist for the transmission of infectious diseases. (D)</p> Signup and view all the answers

    Which age group is most likely to be affected by infectious diseases?

    <p>Infants (A)</p> Signup and view all the answers

    What is a primary reason for the decrease in mortality rates over time?

    <p>Increased sanitation (C)</p> Signup and view all the answers

    Which of the following is NOT considered a major group of pathogens that infect humans?

    <p>Nutrients (B)</p> Signup and view all the answers

    What is the primary goal of 'flattening the curve' during an epidemic?

    <p>To slow the spread of infection to manage healthcare resources (B)</p> Signup and view all the answers

    In which type of country are individuals more likely to die from infectious diseases rather than chronic diseases?

    <p>Lower-middle income countries (B)</p> Signup and view all the answers

    What happens to the immune system as age increases?

    <p>It becomes weaker (C)</p> Signup and view all the answers

    Why do new diseases, such as zoonotic diseases, continue to emerge?

    <p>Pathogens reproduce more quickly than hosts, leading to evolution (A)</p> Signup and view all the answers

    What does the term 'virulence' refer to in the context of infectious diseases?

    <p>The severity of a disease caused by a pathogen (C)</p> Signup and view all the answers

    What does the 'epidemic curve' indicate in terms of public health?

    <p>The pattern of infection incidence over a specific time frame (D)</p> Signup and view all the answers

    What is a reason that the immune system may not fully develop in certain environments?

    <p>Living in a low resource environment (C)</p> Signup and view all the answers

    What is a defining characteristic of prions?

    <p>They are infectious proteins. (D)</p> Signup and view all the answers

    Which disease is associated with prion infection in humans?

    <p>Kuru (D)</p> Signup and view all the answers

    What is the primary mode of transmission for vector-borne diseases?

    <p>Through intermediary species such as insects (C)</p> Signup and view all the answers

    Which factor is associated with increased virulence in pathogens according to evolutionary theory?

    <p>Use of disease vectors for transmission (D)</p> Signup and view all the answers

    What is a common transmission method for respiratory pathogens?

    <p>Droplet transmission (C)</p> Signup and view all the answers

    Which of the following diseases is NOT caused by prions?

    <p>Tuberculosis (D)</p> Signup and view all the answers

    What role does the skin play in pathogen transmission?

    <p>It is a common entry point due to thin epithelial tissues. (D)</p> Signup and view all the answers

    What is a significant requirement for a pathogen to evolve to lower virulence?

    <p>Creating conditions through disrupted transmission modes (C)</p> Signup and view all the answers

    Which of the following is NOT one of Koch's postulates?

    <p>The pathogen must have a known vector (A)</p> Signup and view all the answers

    Which type of organism is characterized by lacking a nucleus and reproducing by duplicating DNA?

    <p>Bacteria (B)</p> Signup and view all the answers

    What characteristic is unique to viruses compared to other infectious agents?

    <p>They cannot complete their life cycle without a host (A)</p> Signup and view all the answers

    Which statement about fungi is INCORRECT?

    <p>Most fungi are harmful to humans (A)</p> Signup and view all the answers

    Which group of pathogens includes multicellular organisms that can cause disease in humans?

    <p>Helminths (C)</p> Signup and view all the answers

    Which of the following statements about protozoa is true?

    <p>They can easily evade the host's immune defenses (B)</p> Signup and view all the answers

    The majority of viral infections depend on which of the following host characteristics?

    <p>The receptor proteins on host cells (B)</p> Signup and view all the answers

    How do helminths typically damage their hosts?

    <p>By feeding on host tissues and nutrients (A)</p> Signup and view all the answers

    Flashcards

    What are pathogens?

    Pathogens are microorganisms that cause disease in humans. They include viruses, bacteria, protozoa, fungi, helminths, and prions.

    What are the 6 main groups of pathogens?

    The six main groups of pathogens are viruses, bacteria, protozoa, fungi, helminths, and prions.

    How does sanitation affect infectious disease?

    Sanitation plays a major role in reducing infectious diseases. It helps to prevent the spread of pathogens by improving hygiene practices and access to clean water.

    What are the main factors contributing to the decline in infectious diseases?

    Factors like improved sanitation, vaccinations, and medications have significantly reduced infectious disease mortality.

    Signup and view all the flashcards

    How does age affect infectious disease?

    Infants and young children are more susceptible to infectious diseases than older adults.

    Signup and view all the flashcards

    Low Resource Environment

    A setting with limited access to healthcare, sanitation, and other essential resources. This often leads to weakened immune systems and increased vulnerability to infections.

    Signup and view all the flashcards

    Epidemic Curve

    A graph showing the incidence of a disease over time, typically characterized by a sharp increase in cases followed by a decline. It represents the spread of a disease through a population.

    Signup and view all the flashcards

    Flattening the Curve

    Strategies aimed at slowing the spread of a disease, not necessarily stopping it, but extending the timeline to reduce the strain on healthcare systems. This is often achieved by social distancing, hygiene practices, and vaccination.

    Signup and view all the flashcards

    Zoonotic Diseases

    Infectious diseases transmitted from animals to humans. These diseases can emerge due to environmental changes, human encroachment, or contact with infected animals.

    Signup and view all the flashcards

    Virulence

    The severity of a disease caused by a pathogen. It can vary depending on factors like the pathogen's ability to spread and its impact on the host.

    Signup and view all the flashcards

    Germ Theory of Disease

    The concept that microorganisms, specifically bacteria, cause infectious diseases. These diseases are caused by the invasion and multiplication of germs within host organisms.

    Signup and view all the flashcards

    Koch's Postulates

    A set of four criteria designed to establish a causal relationship between a specific microbe and a specific disease.

    Signup and view all the flashcards

    What is the first of Koch's postulates?

    The specific pathogen must always be found in persons suffering from the disease but should not be found in healthy individuals.

    Signup and view all the flashcards

    What is the second of Koch's postulates?

    The pathogen must be isolated from the diseased host and grown in pure culture.

    Signup and view all the flashcards

    What is the third of Koch's postulates?

    The cultured pathogen should cause the disease when introduced into a healthy individual.

    Signup and view all the flashcards

    What is the fourth of Koch's postulates?

    The pathogen must be isolated again from the inoculated, now diseased, individual and match the original pathogen.

    Signup and view all the flashcards

    What is a virus?

    A tiny infectious agent that replicates only inside the living cells of other organisms. They are made up of a protein coat surrounding DNA or RNA.

    Signup and view all the flashcards

    What are bacteria?

    Single-celled organisms without a nucleus. They reproduce by duplicating their DNA and dividing into two daughter cells.

    Signup and view all the flashcards

    Prions

    Infectious proteins that lack RNA or DNA and cause transmissible spongiform encephalopathies (TSEs).

    Signup and view all the flashcards

    TSEs

    Transmissible spongiform encephalopathies are fatal neurodegenerative diseases caused by prions, leading to brain damage resembling a sponge.

    Signup and view all the flashcards

    Kuru

    A TSE found in humans, primarily affecting the Fore people of Papua New Guinea, transmitted through ritualistic cannibalism.

    Signup and view all the flashcards

    Direct Transmission

    The spread of pathogens through direct contact with infected individuals or contaminated materials.

    Signup and view all the flashcards

    Epithelial Cells

    Cells forming a protective layer in the body's outer regions, including skin, respiratory, digestive systems, and reproductive tracts.

    Signup and view all the flashcards

    Droplet Transmission

    Spread of pathogens through respiratory droplets expelled by coughing, sneezing, or talking within a short distance (less than 1 meter).

    Signup and view all the flashcards

    Vector-borne Transmission

    Spread of pathogens via intermediate species (like insects or animals) or materials (like food, water, or objects) that carry the pathogen.

    Signup and view all the flashcards

    Evolution of Virulence

    The change in the severity of a pathogen over time, influenced by factors like transmission methods and host mobility.

    Signup and view all the flashcards

    Infectious Disease

    A disease caused by microorganisms that use a host's resources to reproduce, leading to an immune response or disruption of the body's normal functions.

    Signup and view all the flashcards

    Host

    The organism that is infected by a specific infectious agent.

    Signup and view all the flashcards

    What is an infectious disease?

    An infectious disease is caused by microorganisms like bacteria, viruses, fungi, or parasites that use the host's resources to reproduce, leading to an immune response or disruption of the body's normal functions.

    Signup and view all the flashcards

    Germ Theory

    The theory that specific microorganisms cause specific diseases.

    Signup and view all the flashcards

    Study Notes

    Course Information

    • Course: Anthropology 243, Medical Anthropology: Human Biology and Health
    • Course year: Fall 2024
    • Textbook: Medical Anthropology: A Biocultural Approach, 4th Edition, by Andrea S. Wiley and John S. Allen

    Announcements

    • Exam 2 grades will be posted by Thursday.
    • Exam 3 is Tuesday, December 10th, 8:00 AM – 9:00 AM in LH 8 (60 minutes).
    • Students with more than two exams within a 24-hour period can request a makeup exam. The professor teaching the largest section of the course will arrange the makeup.

    Schedule

    • Schedule up to Thanksgiving Break.
    • Tuesday, November 12th: Introduction to Infectious Diseases (Chapter 8).
    • Thursday, November 14th: Guest lecture by Meg Gauck on Colonialism and Tuberculosis.
    • Tuesday, November 19th: The Immune System.
    • Thursday, November 21st: Film Discussion: Bending the Arc.
    • Tuesday, November 26th: No class (Friday classes meet).
    • Thursday, November 28th: No class (Thanksgiving Break).

    Infectious Disease I (Wiley & Allen Ch. 8)

    • Textbook chapter: Wiley and Allen, Chapter 8: 240-248
    • What is infectious disease?
    • Epidemiology
    • Germ theory and Koch's postulates
    • Types of infectious diseases
    • Infectious disease transmission

    What is an Infectious Disease?

    • Microorganisms use hosts' resources for reproduction, disrupting the immune response or physiology.
    • Host: the organism the infection targets.
    • Most microorganisms don't cause disease. Pathogens (germs) do.
    • Six major pathogen groups that infect humans: viruses, bacteria, protozoa, fungi, helminths, and prions.
    • Exposure and susceptibility vary.

    Deaths from Major Infectious Diseases

    • Data showing declines in deaths from infectious diseases over time, correlating with the introduction of vaccines and treatments.
    • Life expectancy has increased significantly.

    Top 10 Causes of Death Globally (2021)

    • Leading causes in 2021: Ischemic heart disease, COVID-19, Stroke, Chronic Obstructive Pulmonary Disease, Lower Respiratory Infections, Trachea, Bronchus, Lung Cancers, Alzheimer's disease and other dementias, Diabetes Mellitus, Kidney Diseases, and Tuberculosis.
    • Differences in mortality rates exist based on the income level of the country (more infections among low/middle income).

    Low-Income Countries Death Causes (2021)

    • Leading causes: Lower respiratory infections, Stroke, Ischemic heart disease, Malaria, Preterm Birth Complications, COVID-19, Diarrhoeal diseases, Tuberculosis, Birth asphyxia and birth trauma, and HIV/AIDS.

    Lower-Middle Income Countries Death Causes (2021)

    • Leading causes: COVID-19, Ischaemic heart disease, Stroke, Chronic obstructive pulmonary disease, Lower respiratory infections, Tuberculosis, Diarrheal diseases, Diabetes mellitus, Cirrhosis of the liver, and Preterm birth complications.

    High-Income Countries Death Causes (2021)

    • Similar to global trends, but with chronic diseases like heart disease and cancer being the leading causes.

    What Age Group is Most Affected?

    • Causes of death for children under five: Prematurity, Acute respiratory infections, Birth asphyxia and birth trauma, Congenital anomalies, Diarrhoea, Neonatal sepsis, Injuries, Malaria, Meningitis/encephalitis, Measles, HIV/AIDS, and Tetanus.

    Top 10 Causes of Death in the US (2023)

    • Leading causes in US 2023: Heart disease, cancer, unintentional injury, stroke, chronic lower respiratory diseases, Alzheimer's disease, diabetes, kidney disease, chronic liver disease and cirrhosis, and COVID-19.

    Epidemic Curve

    • Epidemic: a rise in the incidence of a disease in a population.

    Flattening the Curve

    • Healthcare systems must accommodate capacity to handle spreading infections. Slowing the rate of spreading is key.

    Why Do We Still Have Infectious Diseases?

    • Conflicts between pathogens and hosts.
    • Pathogen vs. human evolution (pathogens reproduce faster).
    • Novel environments—like antibiotic resistance.

    New Diseases

    • Zoonotic diseases: transferred from animals to humans.

    Changes in Virulence

    • Virulence: severity of a disease caused by a pathogen.

    How do we know that a set of symptoms result from an infection?

    • Koch's Postulates are the criteria we use to determine if a disease is infectious.

    Classes of Infectious Disease

    • Viruses, Bacteria, Protozoa, Fungi, Helminths, and Prions

    Viruses

    • DNA or RNA surrounded by protein.
    • Obligate parasites that can't complete their life cycle without a host.
    • Mimic host cell proteins to gain entry.
    • Hosts are carriers of the infections.

    Bacteria

    • Single-celled prokaryotes (no nucleus)
    • Reproduce by duplicating their DNA and dividing.
    • Over 400 genera; 40 known to cause human disease.
    • 10x the number of bacterial cells compared to human cells.
    • Significant diversity in survivability outside the host
    • Variety in form (spores, flagella, pili)
    • Able to survive in a variety of environments (aerobic, anaerobic)

    Protozoa

    • Single-celled eukaryotes with a nucleus.
    • Able to evade host immune systems.
    • Infections are difficult to treat; cellular structures similar to the host.
    • Variability in reproduction and growth stages (different organs, intermediate species, vector transmission).
    • Vector= agent that carries and transmits pathogen.

    Fungi

    • Eukaryotes with a nucleus.
    • 70,000 species; few harmful to humans.
    • Low virulence unless the host is immunocompromised.
    • Highly variable (yeasts, spores).

    Helminths (Worms)

    • Multicellular organisms
    • 3 types cause human disease (roundworms, tapeworms, flukes).
    • 50% of global population is infected today (historic high).
    • Difficult to treat (tough outer coatings).
    • Transmission through intermediate hosts (water, soil, food).

    Prions

    • Infectious proteins, rather than DNA/RNA
    • Unknown replication mechanism.
    • Transmissible spongiform encephalopathies (TSEs), a group of neurodegenerative diseases.
    • Human (Creutzfeldt-Jakob disease, Kuru)
    • Animal (Bovine spongiform encephalopathy, Scrapie).
    • Transmission can be through exposure to infected brain tissue or spinal fluid

    How are Pathogens Spread?

    • Direct transmission (contact).
    • Droplet transmission (less than 1 meter).
    • Vector-borne (insects, animals, contaminated objects).

    Evolution of Virulence

    • Factors affecting pathogen virulence:
    • Intermediate disease vectors
    • Transmission (mobile host vs non-mobile host)
    • Casual human-to-human transmission

    Next Time

    • Guest lecture from Meg Gauck.
    • Attendance and participation required.

    Studying That Suits You

    Use AI to generate personalized quizzes and flashcards to suit your learning preferences.

    Quiz Team

    Related Documents

    Description

    Test your knowledge on infectious diseases with this quiz covering key concepts such as microorganisms, Koch's postulates, and transmission dynamics. Understand the significance of age and environment in disease susceptibility, and explore what defines a host and virulence. This quiz is a great review for anyone studying public health or microbiology.

    More Like This

    Principles of Infectious Diseases Intro
    36 questions
    Ch 1 microbiology
    1 questions

    Ch 1 microbiology

    BeneficiaryUranium avatar
    BeneficiaryUranium
    Infectious Diseases Diagnostics Overview
    41 questions
    Microbiology_8_Disease
    39 questions

    Microbiology_8_Disease

    FrugalCombination3009 avatar
    FrugalCombination3009
    Use Quizgecko on...
    Browser
    Browser