Infectious Diseases Overview
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Questions and Answers

What is the basic reproductive rate of a disease?

  • The proportion of people who are exposed and become infected
  • The total number of cases reported in a population
  • The average number of secondary cases caused by one infected individual (correct)
  • The average number of people who die from the disease

Which type of disease primarily affects the poorest countries?

  • Vector-borne diseases
  • Neglected Tropical Diseases (correct)
  • Zoonotic diseases
  • Emerging infectious diseases

What defines an emerging infectious disease?

  • A disease that can be completely eradicated
  • A disease that appears for the first time or is rapidly increasing in incidence (correct)
  • A disease that is rapidly decreasing in incidence
  • A disease that has existed for many years but is declining

Which of the following is an example of a zoonotic disease?

<p>Rabies (D)</p> Signup and view all the answers

What does the secondary attack rate measure?

<p>The number of people who are infected after an initial case (D)</p> Signup and view all the answers

What does the One Health approach primarily focus on?

<p>The interconnection between human and animal well-being (D)</p> Signup and view all the answers

Which factor does NOT influence the movement of people and animals according to the One Health concept?

<p>Climate change (D)</p> Signup and view all the answers

Which disease is NOT classified as zoonotic?

<p>Influenza (A)</p> Signup and view all the answers

What is a potential consequence of anti-microbial resistant germs in the context of One Health?

<p>It complicates treatment of infections for both humans and animals (B)</p> Signup and view all the answers

What role does the health of local animal populations play in assessing human health risks?

<p>It often predicts risks to human health (B)</p> Signup and view all the answers

What describes the time from infection to the onset of symptoms?

<p>Incubation period (C)</p> Signup and view all the answers

Which factors contribute to a weaker immune system, making individuals more susceptible to infectious diseases?

<p>Drugs and preexisting conditions (D)</p> Signup and view all the answers

What is the term for individuals who do not show symptoms but can still spread an infection?

<p>Carriers (C)</p> Signup and view all the answers

What does 'case fatality' measure in relation to infectious diseases?

<p>The proportion of deaths among infected individuals (B)</p> Signup and view all the answers

What historical example illustrates the impact of infectious diseases on mortality rates?

<p>The 1918 pandemic (A)</p> Signup and view all the answers

What percentage of all infectious diseases is attributed to vector-borne diseases?

<p>17% (B)</p> Signup and view all the answers

Which of the following is NOT a means of transmission of diseases?

<p>Direct contact (D)</p> Signup and view all the answers

Who was Typhoid Mary and what was her significance in relation to disease transmission?

<p>An asymptomatic carrier of typhoid fever who infected others (D)</p> Signup and view all the answers

What is a reservoir in the context of the chain of infection?

<p>A living or nonliving place where the pathogen lives and multiplies (C)</p> Signup and view all the answers

Which of the following actions is part of epidemiologic surveillance?

<p>Quarantining and contact tracing (B)</p> Signup and view all the answers

What is the purpose of breaking the chain of infection?

<p>To control and contain one aspect of disease spread (C)</p> Signup and view all the answers

Which vector is specifically mentioned as transmitting malaria?

<p>Mosquitoes (B)</p> Signup and view all the answers

What type of pathogens can be transmitted through aerosols?

<p>Viruses, bacteria, or parasites (B)</p> Signup and view all the answers

What is the primary goal of breaking Link 1 in the chain of infection?

<p>Target the pathogen with treatments (B)</p> Signup and view all the answers

Which action is crucial for breaking Link 2 in the chain of infection?

<p>Removing the pathogen's reservoir (D)</p> Signup and view all the answers

How can Link 3 be broken in the chain of infection?

<p>Quarantining affected individuals (A)</p> Signup and view all the answers

What method is mentioned as a way to break Link 4 in the chain of infection?

<p>Administering vaccines (D)</p> Signup and view all the answers

In unique cases like malaria, what is considered an additional chain that can be addressed?

<p>Skin (D)</p> Signup and view all the answers

What is the primary function of surveillance systems in breaking the chain of infection?

<p>To identify individuals who may have contracted a pathogen (B)</p> Signup and view all the answers

What is a key feature of the syphilis tracking system in the prison system?

<p>Anonymous notification of sexual contacts (C)</p> Signup and view all the answers

In approaching the chain of infection, what is emphasized by the modern perspective?

<p>Breaking the weakest link in the chain (C)</p> Signup and view all the answers

Flashcards

Infectious Disease

A disease caused by infectious agents like viruses, bacteria, parasites, or fungi.

Incubation Period

The time between infection and the appearance of symptoms.

Clinical Stage

The stage of an infection when symptoms appear.

Infectious Period

The time during which an infected person can spread the disease.

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Disease Carrier

A person who is infected but shows no symptoms, yet can still spread the disease.

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Case Fatality Rate

The percentage of people with a disease who die from it.

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Basic Reproductive Rate

The average number of new cases generated by one infected individual.

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Zoonotic Disease

A disease that can be transmitted from animals to humans.

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Emerging Infectious Disease

A disease appearing for the first time or rapidly increasing in incidence.

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Neglected Tropical Diseases

Diseases primarily affecting poor countries.

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Vector-borne disease

Diseases transmitted by insects or animals carrying pathogens.

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Vector

An animal that carries pathogens between hosts.

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Fecal-oral route

Transmission of disease through contaminated water or food.

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Carrier state

An infected person showing no symptoms but still capable of spreading the disease.

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Chain of infection

The sequence of events needed for a disease to spread.

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Reservoir

A place where a pathogen lives and multiplies.

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Method of transmission

How a pathogen moves from one host to another.

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Susceptible host

Organism lacking immunity, vulnerable to infection.

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One Health

A public health approach that focuses on the interconnectedness of human, animal, and environmental health.

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Anti-microbial Resistant Germs

Germs that become resistant to antibiotics, making infections harder to treat in both humans and animals.

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Human-Animal Bond

The positive relationship between humans and animals, which can improve their well-being.

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Where to break the chain

The decision of where to break the chain of infection depends on the disease's vulnerability, effectiveness of intervention, and associated risks at each link.

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Breaking Link 1: Targeting the pathogen

Using antibiotics or antiviral treatments specifically targets the pathogen, preventing further infection in hosts.

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Breaking Link 2: Removing the reservoir

Eliminating the pathogen's ideal reproductive conditions, such as its food source or environment, prevents its spread.

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Breaking Link 3: Isolating transmission

Quarantining infected individuals to prevent further spread of the disease.

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Breaking Link 4: Preventing transmission impact

Administering vaccines provides immunity, minimizing the impact of the disease on the population.

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Breaking additional chains

In some cases, like malaria, additional factors might be considered part of the chain of infection, such as skin exposure, requiring specific interventions like wearing long sleeves.

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Modern perspective: Weakest link

Modern approaches focus on identifying individuals who have had contact with a pathogen and providing treatment to contain its spread.

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Contact tracing example

The syphilis tracking system in prisons is a prime example of contact tracing, where infected inmates identify their contacts, who are anonymously notified and treated.

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Study Notes

Infectious Disease

  • Infectious disease is caused by agents like viruses, bacteria, parasites, and fungi.
  • Advances in nutrition, antibiotics, immunization, food safety, housing, and sanitation have reduced infectious diseases.
  • Historical examples include smallpox, TB, syphilis, cholera, and plague, which were major causes of death. The 1918 pandemic resulted in 40 million deaths.

Mechanism of Infection

  • When an organism enters the body, the immune system fights it.
  • Factors influencing disease development include weakened immune systems from drugs, age, existing conditions, or lack of vaccination.

Stages of Infection

  • Incubation period: Time between infection and symptom onset.
  • Clinical stage: Marked by symptom appearance.
  • Infectious period: Time during which infected person can spread the disease.

Infection from Exposure to Recovery

  • The diagram shows the stages from exposure to infection, followed by the recovery period.

Carriers

  • Carriers are asymptomatic individuals who can still spread disease.
  • Case fatality rate: Proportion of infected individuals who die. Example: 6 out of 10 people with a disease die, resulting in a 60% case fatality rate.

Basic Reproductive Rate

  • Measures how infectious a disease is.
  • Average number of secondary cases from one infected individual.

Secondary Attack Rate

  • Proportion of exposed individuals who develop the infection.

Infectious Disease Types

  • Zoonotic Diseases: Animal-to-human transmission.
    • 60% of human infectious diseases are zoonotic.
    • Examples: Leptospirosis (mice), toxoplasmosis (cats), Campylobacter (chicken), and rabies.
  • Emerging Infectious Diseases: Newly appearing or rapidly increasing diseases.
    • Examples: Ebola, MERS-CoV, Hendra, new influenza strains.
  • Neglected Tropical Diseases (NTDs): Affect poor countries.
    • Examples: Leishmaniasis, Trachoma, sleeping sickness, Schistosomiasis.

Vector-Borne Diseases

  • Transmitted from one animal or human to another via an insect or animal vector.
    • Examples: Malaria, Dengue, sleeping sickness, schistosomiasis.
  • Vector-borne diseases represent over 17% of all infectious diseases and cause approximately one million deaths annually.

Means of Transmission

  • Vectors: Insects or animals carrying pathogens.
  • Aerosols: Water droplets containing pathogens from coughing or sneezing.
  • Fecal-oral route: Transmission via contaminated water or food.
  • Carrier state: Asymptomatic carriers who can still transmit disease.

Chain of Infection

  • Link 1: Pathogen (virus, bacterium, parasite)
  • Link 2: Reservoir (where pathogen lives and multiplies)
  • Link 3: Method of transmission (how pathogen moves)
  • Link 4: Susceptible host (organism vulnerable to infection)

Breaking the Chain of Infection

  • Targeting the pathogen (antibiotics, antivirals).
  • Removing the reservoir.
  • Isolating the means of transmission (quarantine, etc.).

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Description

Explore the critical aspects of infectious diseases, including their causes, mechanisms of infection, and stages from exposure to recovery. This quiz covers historical examples, the impact of nutrition and sanitation, and factors influencing disease development. Test your knowledge on how diseases spread and the immune system's response.

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