ID & HEME

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Questions and Answers

An 80-year-old patient is admitted with pneumonia. Which of the following is most indicative of a bacterial infection in this age group, considering atypical presentations?

  • Productive cough with green sputum
  • High fever (above 102°F)
  • Elevated white blood cell count with marked leukocytosis
  • Sudden onset of confusion (correct)

Which factor most significantly contributes to the increased morbidity and mortality associated with infections in older adults?

  • Higher rates of smoking compared to younger adults
  • Increased exposure to pathogens in crowded living facilities
  • Poor adherence to prescribed antibiotic regimens
  • Decline in both B- and T-cell immunity (correct)

An 85-year-old nursing home resident is evaluated for possible pneumonia. Which atypical presentation is vital when assessing for pneumonia?

  • High fever and productive cough
  • Confusion and tachypnea (correct)
  • Fatigue and reduced appetite
  • Sharp chest pain exacerbated by breathing

In an elderly patient presenting with a urinary tract infection (UTI), what is the most crucial consideration regarding antibiotic treatment?

<p>Avoid antibiotics unless the patient is symptomatic to reduce resistance. (C)</p> Signup and view all the answers

What is the recommended approach to managing asymptomatic bacteriuria in an elderly female patient?

<p>Monitor for symptoms of UTI and treat only if symptoms develop. (B)</p> Signup and view all the answers

Which of the following is the strongest risk factor for developing postherpetic neuralgia (PHN) after a herpes zoster (HZ) infection in an older adult?

<p>Increased age (A)</p> Signup and view all the answers

An 82-year-old patient has a herpes zoster infection. When should antiviral treatment be initiated to most effectively reduce acute pain and chronic pain?

<p>Within 72 hours of rash onset (B)</p> Signup and view all the answers

An 70-year-old is due for several vaccinations. According to current guidelines, which vaccination is recommended at age 60 years or older?

<p>Herpes zoster vaccine (B)</p> Signup and view all the answers

An 68-year-old patient with a history of COPD is being vaccinated. What is the correct sequence for administering pneumococcal vaccines?

<p>Administer PCV13 first, followed by PPSV23 six to twelve months later. (D)</p> Signup and view all the answers

Which of the following cardiovascular conditions is a common underlying cause of infective endocarditis (IE) in older adults?

<p>Atherosclerotic and degenerative valve disease (C)</p> Signup and view all the answers

What is the most common pathogen causing septic arthritis in older adults?

<p>Staphylococcus aureus (A)</p> Signup and view all the answers

When evaluating older residents in long-term care facilities (LTCFs) for possible infections, what should clinicians recognize regarding fever?

<p>Absence of fever is common, even in the presence of serious infections. (C)</p> Signup and view all the answers

An 88-year-old resident of a long-term care facility presents with a decline in functional status and increased confusion. What should be the initial step?

<p>Assess for other signs of infection and consider diagnostic testing. (D)</p> Signup and view all the answers

An 75 year old new LTCF resident with an indwelling urinary catheter develops a fever. What is the next step?

<p>Replace the catheter, obtain a urine culture from the new catheter, and initiate antibiotics based on local guidelines. (D)</p> Signup and view all the answers

Which of the following is an important consideration when evaluating a long-term care facility resident for a respiratory viral infection outbreak?

<p>Obtain a nasopharyngeal swab for virus isolation and rapid diagnostic testing. (B)</p> Signup and view all the answers

What is the most important factor to consider when screening older adults for cancer?

<p>Availability of an effective intervention (B)</p> Signup and view all the answers

According to the USPSTF, what is the upper age limit for recommending routine screening for colorectal cancer?

<p>75 years (B)</p> Signup and view all the answers

A 78-year-old man asks about prostate cancer screening. According to the USPSTF, what is generally recommended regarding PSA screening in men of this age?

<p>Screening for prostate cancer is not recommended. (A)</p> Signup and view all the answers

Which of the following is a major diagnostic criterion for multiple myeloma (MM)?

<p>Lytic bone lesions (B)</p> Signup and view all the answers

What is the typical RBC morphology seen in anemia of chronic disease (ACD)?

<p>Hypochromia (B)</p> Signup and view all the answers

A 72-year-old male is newly diagnosed with Vitamin B12 deficiency. What is the best treatment choice for this patient?

<p>Vitamin B12(at an oral replacement dose of 1000 to 2000 mcg/day. (B)</p> Signup and view all the answers

What is the classic triad seen in multiple myeloma?

<p>Marrow plasmacytosis, lytic bone lesions, monoclonal antibody spike (D)</p> Signup and view all the answers

What is the most common leukemia in the Western world?

<p>Chronic lymphocytic leukemia (C)</p> Signup and view all the answers

What is the classic treatment for polycythemia vera?

<p>Phlebotomy and maintain Hct at 45% (B)</p> Signup and view all the answers

Q1: A 70-year-old female presents to her primary care office for a yearly check-up. She has a history of DM and HTN both of which are managed with oral therapy. She is chronically fatigued but has no other specific complaints. PE discloses several 1-to 2 cm nodes on both sides of the anterior neck and in the axilla. Routine CBC reveals that her WBC is 98,000 mainly due to preponderance of mature-appearing lymphocytes (see below). Her hematocrit is 38.2% and her platelet count is 250,000/uL. Except for a mildly elevated LDH her serum chemistries are normal. Serum protein electrophoresis reveals mild hypogammaglobulinemia. A CT scan of the chest, abdomen, and the pelvis discloses multiple 1-2 cm lymph nodes in the peri-aortic area. What is the most likely diagnosis in this woman?

<p>CLL (B)</p> Signup and view all the answers

Q2: A figure skater who won gold medals at the 1928, 1932, and 1936 Winter Olympic games became progressively fatigued her late 50's, leading to a workup that revealed a CBC with Hgb 10.1 g/dL, Hct 30.5%, MCV 90 fL, platelet count 89,000/uL, and WBC count 31,300/uL. From the peripheral blood picture shown here, the most likely diagnosis is:

<p>Chronic lymphocytic leukemia (D)</p> Signup and view all the answers

Q 3: A 55-year-old man presents with bone pain that is aggravated by movement or weight bearing. Physical examination is remarkable for pale conjunctiva. Laboratory results show a normocytic anemia and an increased serum globulin level. Peripheral blood smear is seen here. Osteolytic bone lesions are seen on a radiograph of the pelvis. Bone scanning is normal. Which of the following is the most likely diagnosis?

<p>Multiple myeloma (A)</p> Signup and view all the answers

Q 4: Which of the following statements concerning screening for colorectal cancer is correct?

<p>Patients who have a positive fecal Hemoccult test while on a low-meat diet are likely to have colorectal carcinoma (B)</p> Signup and view all the answers

Q 5: Which of the following statements about fecal occult blood testing is correct?

<p>None of the above (D)</p> Signup and view all the answers

Q6: Screening for prostate cancer with Prostate-specific antigen (PSA) is controversial because:

<p>All of the above (D)</p> Signup and view all the answers

Q7: Which of the following statements concerning catheter-associated urinary infections is common

<p>Most patients catheterized for longer than 2 weeks develop bacteriuria (B)</p> Signup and view all the answers

Q 8: A 69-year-old PA was well until 3 weeks ago when she developed a urinary tract infection. She was treated with ampicillin for 10 days, taking her last dose 7 days ago. Four days ago, she developed abdominal pain, fever, and bloody diarrhea. On examination, she appears acutely ill; her temperature is 101 F and her abdomen is diffusely tender. Sigmoidoscopy demonstrates a hyperemic mucosa studded with plaque-like lesions. The most likely diagnosis is

<p>Pseudomembranous colitis (A)</p> Signup and view all the answers

Q 9: A 75-year-old woman has had increasing fatigue with a 3 kg weight loss over the past 7 months. Her hands become purple and painful upon exposure to cold. On physical examination, she has a palpable spleen tip. Laboratory studies show Hgb 10.5 g/dL, Hct 31.7%, MCV 99 fL, platelet count 193,600/microliter, and WBC count 5390/microliter. The direct Coombs test is positive at 4 C and negative at 37 C. Which of the following underlying diseases is this woman most likely to have?

<p>Non-Hodgkin lymphoma (B)</p> Signup and view all the answers

Q10: A 72-year-old man presents for his annual health maintenance visit. The review of systems is positive for occasional fatigue and headache. The patient admits to generalized pruitis following a warm bath or shower. He has plethora and engorgement of the retinal veins. A spleen is palpable on abdominal examination. The patient's hematocrit is 63% and he has a leucocytes and thrombocytosis. Peripheral blood smear is normal. The patient does not smoke. Which of the following is the most likely diagnosis?

<p>Polycythemia vera (C)</p> Signup and view all the answers

In older adults, what distinguishes a lower hemoglobin concentration as a sign of disease, mortality, and hospitalization?

<p>A low hemoglobin concentration signifies disease with increased mortality, disability, and hospitalization. (A)</p> Signup and view all the answers

What anemia is the most common with a known etiology in older adults?

<p>Iron Deficiency Anemia (B)</p> Signup and view all the answers

What are the signs and symptoms of Anemia in an older adult?

<p>All of the above (D)</p> Signup and view all the answers

Which cause of anemia must have have a dietary evaluation done, regardless if they have had poor nutrition?

<p>Iron Deficiency Anemia (C)</p> Signup and view all the answers

Which of the following physiological changes in older adults is MOST likely to contribute to an increased susceptibility to infections?

<p>Decline in B-cell and T-cell immunity (C)</p> Signup and view all the answers

An 80-year-old patient in a long-term care facility is suspected of having an infection. Which clinical finding, while common in younger adults, is LEAST reliable as an indicator of infection in this older adult population?

<p>Fever (D)</p> Signup and view all the answers

A 75-year-old patient is diagnosed with pneumonia. Compared to younger adults with pneumonia, older adults are MORE likely to present with:

<p>Confusion and tachypnea (B)</p> Signup and view all the answers

Which of the following pathogens is MORE frequently associated with pneumonia in older adults, particularly in long-term care facilities, compared to community-acquired pneumonia in younger adults?

<p><em>Haemophilus influenzae</em> (D)</p> Signup and view all the answers

An 82-year-old female resident in a nursing home presents with new onset confusion and increased falls. She has no fever. Which of the following should be the INITIAL diagnostic consideration?

<p>Urinary tract infection (A)</p> Signup and view all the answers

What is the MOST appropriate management approach for asymptomatic bacteriuria discovered during routine urinalysis in an 85-year-old woman residing in assisted living?

<p>Monitor for symptoms of UTI and avoid antibiotic treatment. (B)</p> Signup and view all the answers

Which of the following is the STRONGEST risk factor for the development of postherpetic neuralgia (PHN) following a herpes zoster infection in an older adult?

<p>Age (B)</p> Signup and view all the answers

An 80-year-old patient presents with herpes zoster. To MOST effectively reduce the duration and severity of acute pain and the risk of PHN, antiviral treatment should be initiated within how many hours of rash onset?

<p>72 hours (B)</p> Signup and view all the answers

According to current guidelines, which vaccination is routinely recommended for adults aged 60 years or older to prevent herpes zoster and its complications?

<p>Herpes zoster vaccine (A)</p> Signup and view all the answers

A 70-year-old patient with a history of COPD is due for pneumococcal vaccinations. What is the CORRECT recommended sequence for administering pneumococcal vaccines in this patient?

<p>Administer PCV13 first, then PPSV23 6-12 months later. (B)</p> Signup and view all the answers

Which of the following cardiovascular conditions is a COMMON underlying risk factor for infective endocarditis (IE) in older adults?

<p>Atherosclerotic and degenerative valve disease (C)</p> Signup and view all the answers

What is the MOST common causative pathogen of septic arthritis in older adults?

<p><em>Staphylococcus aureus</em> (D)</p> Signup and view all the answers

When evaluating a resident in a long-term care facility for a possible infection, a temperature of what value should be considered a fever, warranting further investigation?

<p>A single oral temperature of &gt; 100°F (37.8°C) or repeated oral temperature of &gt; 99°F (37.2°C) (B)</p> Signup and view all the answers

An 88-year-old long-term care facility resident presents with a sudden decline in functional status and increased confusion. What is the MOST appropriate INITIAL step in evaluating this patient?

<p>Obtain a urine sample for urinalysis and culture. (B)</p> Signup and view all the answers

A 75-year-old new resident of a long-term care facility with an indwelling urinary catheter develops a fever. What is the NEXT BEST step in management?

<p>Evaluate for catheter-associated urinary tract infection (CAUTI). (C)</p> Signup and view all the answers

During a respiratory viral infection outbreak in a long-term care facility, what is the MOST important specimen to obtain from residents with suspected infection for diagnostic purposes?

<p>Nasopharyngeal swab or wash (D)</p> Signup and view all the answers

What is the MOST significant risk factor for cancer overall?

<p>Age (B)</p> Signup and view all the answers

According to the USPSTF guidelines for colorectal cancer screening, routine screening is generally recommended to continue until what age in average-risk individuals?

<p>Age 75 (A)</p> Signup and view all the answers

A 78-year-old man asks about prostate cancer screening. According to USPSTF recommendations, what is the general guidance regarding PSA screening in men of this age?

<p>PSA screening is not recommended due to lack of benefit. (D)</p> Signup and view all the answers

What is the typical red blood cell (RBC) morphology observed in anemia of chronic disease (ACD)?

<p>Normocytic, normochromic (D)</p> Signup and view all the answers

A 72-year-old male is newly diagnosed with Vitamin B12 deficiency. Assuming no neurological symptoms, what is the MOST appropriate initial treatment?

<p>Oral Vitamin B12 supplementation at a high dose. (D)</p> Signup and view all the answers

What is the classic triad of findings associated with multiple myeloma (MM)?

<p>Bone pain, anemia, hypercalcemia (D)</p> Signup and view all the answers

Which type of leukemia is the MOST common in the Western world?

<p>Chronic lymphocytic leukemia (CLL) (C)</p> Signup and view all the answers

What is the cornerstone of initial treatment for polycythemia vera to reduce the risk of thrombotic complications?

<p>Phlebotomy (D)</p> Signup and view all the answers

In older adults, a lower hemoglobin concentration is more likely to be indicative of disease, increased mortality, and hospitalization when it is associated with:

<p>Unexplained anemia without obvious cause (C)</p> Signup and view all the answers

Which type of anemia is the MOST common anemia with a known etiology in older adults?

<p>Iron deficiency anemia (C)</p> Signup and view all the answers

Which of the following is an IMPORTANT sign or symptom of anemia in older adults that may be easily overlooked or attributed to other age-related conditions?

<p>Confusion (D)</p> Signup and view all the answers

In an older adult diagnosed with iron deficiency anemia, even in the presence of poor nutrition, what further evaluation is MANDATORY to identify the underlying cause?

<p>Evaluation for a bleeding lesion (D)</p> Signup and view all the answers

A 70-year-old female presents with fatigue and lymphadenopathy. Her CBC shows a WBC count of 98,000 with 90% lymphocytes. Peripheral blood smear shows mature lymphocytes. CT scan reveals widespread lymphadenopathy. Serum protein electrophoresis shows mild hypogammaglobulinemia. What is the MOST likely diagnosis?

<p>Chronic Lymphocytic Leukemia (CLL) (A)</p> Signup and view all the answers

A 60-year-old patient presents with fatigue and easy bruising. Lab results show Hgb 10.1 g/dL, platelets 89,000/uL, WBC 31,300/uL with mature lymphocytes on peripheral smear. What is the MOST likely diagnosis?

<p>Chronic Lymphocytic Leukemia (CLL) (C)</p> Signup and view all the answers

A 55-year-old man presents with bone pain and fatigue. Labs show normocytic anemia and increased serum globulin. Peripheral blood smear shows rouleaux formation. Radiographs reveal osteolytic lesions. Bone scan is normal. What is the MOST likely diagnosis?

<p>Multiple Myeloma (A)</p> Signup and view all the answers

Which of the following statements regarding fecal occult blood testing (FOBT) for colorectal cancer screening is CORRECT?

<p>Rehydration of FOBT slides can increase the positivity rate. (B)</p> Signup and view all the answers

Screening for prostate cancer with Prostate-Specific Antigen (PSA) is controversial for several reasons. Which of the following is a PRIMARY reason for this controversy?

<p>Non-malignant conditions can elevate PSA, leading to false positives and unnecessary biopsies. (A)</p> Signup and view all the answers

Which of the following statements concerning catheter-associated urinary tract infections (CAUTIs) is CORRECT?

<p>Most patients catheterized for longer than 2 weeks will develop bacteriuria. (D)</p> Signup and view all the answers

A 69-year-old female develops abdominal pain, fever, and bloody diarrhea four days after completing a 10-day course of ampicillin for a UTI. Sigmoidoscopy shows pseudomembranous plaques. What is the MOST likely diagnosis?

<p>Pseudomembranous colitis (<em>Clostridium difficile</em> infection) (B)</p> Signup and view all the answers

A 75-year-old woman presents with fatigue, weight loss, and painful purple hands on cold exposure. Labs show anemia, macrocytosis, and a positive direct Coombs test at 4°C but negative at 37°C. Which underlying condition is MOST likely?

<p>Non-Hodgkin lymphoma (D)</p> Signup and view all the answers

A 72-year-old man presents with fatigue, headache, pruritus after warm baths, plethora, and splenomegaly. Hematocrit is 63%, with leukocytosis and thrombocytosis. Peripheral blood smear is normal. What is the MOST likely diagnosis?

<p>Polycythemia Vera (B)</p> Signup and view all the answers

A 78-year-old man from a long-term care facility presents with confusion, absent fever, and mild tachypnea. Chest radiography initially appears normal. Which infection should be strongly suspected based on this atypical presentation?

<p>Pneumonia (D)</p> Signup and view all the answers

A 75-year-old woman has bacteriuria detected incidentally on a routine urinalysis during her annual physical. She has no urinary symptoms. What is the most appropriate management for this patient?

<p>No antibiotic therapy indicated (B)</p> Signup and view all the answers

An 85-year-old man develops painful vesicular lesions along one side of his chest wall. He presents within 24 hours of symptom onset. Which of the following is the most appropriate initial treatment?

<p>Antiviral therapy (acyclovir, famciclovir, or valacyclovir) (A)</p> Signup and view all the answers

Which of the following vaccines is recommended annually for all individuals over the age of 65?

<p>Influenza vaccine (C)</p> Signup and view all the answers

A 70-year-old female nursing home resident is evaluated for suspected pneumonia. Which of the following diagnostic steps is most appropriate to perform initially?

<p>Pulse oximetry if respiratory rate &gt;25 (D)</p> Signup and view all the answers

An 80-year-old patient with anemia presents with hypochromic red blood cells, elevated serum iron, and ringed sideroblasts on bone marrow biopsy. Which of the following treatments is most appropriate?

<p>Oral pyridoxine (Vitamin B6) (B)</p> Signup and view all the answers

A 68-year-old man presents with progressive fatigue and lymphadenopathy. CBC reveals lymphocyte count of 90,000 cells/mm³. Peripheral smear shows mature lymphocytes. The malignant cells test positive for CD5. Which diagnosis is most likely?

<p>Chronic lymphocytic leukemia (CLL) (C)</p> Signup and view all the answers

An 80-year-old patient presents with chronic lower back pain, normocytic anemia, and elevated serum globulins. Imaging shows multiple lytic bone lesions. What condition is most consistent with these findings?

<p>Multiple myeloma (C)</p> Signup and view all the answers

Which hematologic disorder is characterized by JAK2 mutation, elevated hematocrit, risk of thrombosis, and generalized proliferation of all blood cell lines, especially red blood cells?

<p>Polycythemia vera (D)</p> Signup and view all the answers

An elderly patient with anemia is evaluated and found to have low serum iron, low transferrin saturation, and elevated ferritin. Which of the following conditions is most likely?

<p>Anemia of chronic disease (D)</p> Signup and view all the answers

An 82-year-old man in a long-term care facility develops acute confusion, functional decline, and new urinary incontinence without fever or significant leukocytosis. Which of the following should be considered first?

<p>Urinary tract infection (B)</p> Signup and view all the answers

An 85-year-old patient recovering from hip surgery develops fever, abdominal cramps, and watery diarrhea after recent antibiotic therapy. Colonoscopy reveals hyperemic mucosa. Which is the most likely causative organism?

<p>Clostridium difficile (D)</p> Signup and view all the answers

A 75-year-old patient presents with fatigue, numbness of lower extremities, and anemia. Labs reveal elevated methylmalonic acid and homocysteine levels. What vitamin deficiency is most likely?

<p>Vitamin B12 (B)</p> Signup and view all the answers

An 88-year-old woman presents with fatigue, weight loss, and Raynaud's phenomenon. Lab evaluation shows mild anemia, thrombocytopenia, and elevated lymphocyte count. Direct Coombs test is positive. What is the most likely underlying diagnosis?

<p>Non-Hodgkin lymphoma (B)</p> Signup and view all the answers

A 70-year-old man complains of headaches, dizziness, pruritus after bathing, and blurred vision. Physical exam reveals splenomegaly and plethoric appearance. Labs show elevated hematocrit and low EPO levels. What diagnosis is most likely?

<p>Polycythemia vera (D)</p> Signup and view all the answers

Which of the following vaccination recommendations is correct for older adults regarding pneumococcal disease prevention?

<p>Prevnar 13 once followed by Pneumovax 23 in 6-12 months (C)</p> Signup and view all the answers

A 73-year-old male nursing home resident develops increased confusion, a respiratory rate of 28 breaths per minute, and reduced food intake. Which initial diagnostic step is appropriate?

<p>Pulse oximetry to evaluate oxygenation (A)</p> Signup and view all the answers

Which of the following findings distinguishes anemia of chronic disease (ACD) from iron deficiency anemia (IDA)?

<p>Elevated ferritin in ACD (A)</p> Signup and view all the answers

A 67-year-old woman presents with fatigue, angular cheilitis, and glossitis. Lab evaluation reveals anemia and low serum ferritin. What is the next most appropriate step in managing this patient?

<p>Initiate oral iron supplementation (A)</p> Signup and view all the answers

A 77-year-old nursing home resident has acute mental status changes, fever, shaking chills, and hypotension. The patient has an indwelling urinary catheter. Which is the most appropriate initial evaluation?

<p>Urinalysis with urine culture (A)</p> Signup and view all the answers

A 77-year-old woman presents with macrocytic anemia and neurological symptoms including paresthesias. Serum methylmalonic acid and homocysteine levels are elevated. Which is the correct treatment for this patient?

<p>Monthly intramuscular Vitamin B12 injections (C)</p> Signup and view all the answers

A 68-year-old man is diagnosed with polycythemia vera. Which medication would specifically help prevent complications associated with hyperuricemia?

<p>Allopurinol (A)</p> Signup and view all the answers

An 80-year-old man complains of fatigue, recurrent infections, and diffuse bone pain. Laboratory findings reveal anemia, hypercalcemia, and a monoclonal spike in serum protein electrophoresis. Which of the following additional findings would support this diagnosis?

<p>Rouleaux formation on peripheral smear (C)</p> Signup and view all the answers

Which of the following statements regarding herpes zoster vaccination in elderly patients is correct?

<p>Vaccination reduces the incidence and severity of postherpetic neuralgia (D)</p> Signup and view all the answers

A 79-year-old woman has had increasing fatigue, pale conjunctiva, exertional dyspnea, and syncope. CBC reveals Hgb of 9.5 g/dL, low serum iron, and elevated total iron binding capacity. What is the most likely diagnosis?

<p>Iron deficiency anemia (C)</p> Signup and view all the answers

A nursing home resident has acute confusion, decreased functional ability, and fever of 101°F following recent antibiotic therapy. You suspect Clostridium difficile infection. Which initial diagnostic test should you order?

<p>Stool assay for C. difficile toxin (B)</p> Signup and view all the answers

According to USPSTF guidelines, how often should mammography screening be performed in women aged 50 to 74 years?

<p>Every 2 years (A)</p> Signup and view all the answers

Which colorectal cancer screening recommendation is correct for an otherwise healthy 65-year-old patient, according to USPSTF guidelines?

<p>Colonoscopy every 10 years (D)</p> Signup and view all the answers

A 70-year-old woman with a 35 pack-year smoking history, who quit smoking 10 years ago, presents for a routine physical exam. According to USPSTF guidelines, which screening test should be recommended?

<p>Chest CT annually (C)</p> Signup and view all the answers

A 69-year-old woman has had consistently normal Pap smears. According to current guidelines, when should cervical cancer screening be discontinued?

<p>Age 65 if previous tests were normal (A)</p> Signup and view all the answers

A 70-year-old female patient without risk factors asks about ovarian cancer screening. What recommendation aligns with current guidelines?

<p>No routine screening recommended (A)</p> Signup and view all the answers

What is the USPSTF recommendation regarding routine clinical skin cancer screening exams in older adults?

<p>No routine clinical skin cancer screening recommended (D)</p> Signup and view all the answers

A 76-year-old patient with no prior history of colorectal abnormalities asks about continuing colorectal cancer screening. According to USPSTF guidelines, which of the following is most appropriate?

<p>Discontinue routine colorectal cancer screening at this age (D)</p> Signup and view all the answers

According to USPSTF guidelines, how frequently should adults aged 65 and older receive influenza vaccinations?

<p>Annually (A)</p> Signup and view all the answers

Flashcards

Atypical Fever in Elderly Patients?

Older adults often have reduced fever response and atypical infection symptoms.

Infection Risk Factors in Older Adults?

More frequent hospital stays, physiological changes, chronic diseases and DM all increase infection risk.

Atypical Pneumonia Presentation in Elderly?

Pneumonia presents atypically, often with confusion and minimal respiratory symptoms.

Healthcare-Associated Pneumonia in Elderly?

Health-care settings and nursing homes increase the risk of pneumonia with broader pathogen spectrum.

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UTI diagnosis in elderly

Difficult to differentiate from asymptomatic bacteriuria, avoid treatment without symptoms.

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Treating Asymptomatic Bacteriuria in Elderly?

Asymptomatic bacteriuria in older individuals does not require routine antibiotic treatment.

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Herpes Zoster (HZ) in Elderly?

Incidence increases with age and it is the strongest risk factor for developing postherpetic neuralgia

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Herpes Zoster Vaccine Effectiveness?

Vaccination reduces cases of HZ by 50% and postherpetic neuralgia by 66%.

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Influenza Vaccine Recommendation for Elderly?

Annual influenza A vaccine is advised for 65+ individuals.

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Pneumococcal Vaccine Schedule

Administer PCV13 first, and then PPSV23 after 6-12 months, revaccinate with PPSV23 in 5 years

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Infective Endocarditis in Elderly?

Infection is often caused by atherosclerotic and degenerative valve disease, or prosthetics, common pathogen is S.pneumoniae

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Septic Arthritis in Elderly?

Synovial fluid exam needed, test for staph and gram negative bacilli.

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Infection in LTCF residents

Consider infection with any change to function

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Anemia in Elderly?

Anemia as Hgb < 7.5 mmol/dL in woman and < 8.1 mmol/dL in men, signifies disease, increased mortality, disability and hospitalization

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Iron Deficiency Anemia Evaluation?

Common GI lesions include diverticulosis, evaluate stool and perform GI lesion evaluation.

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Differentiating Anemia of Chronic Disease?

Low RBC and low serum iron may lead to confusion with iron deficiency. Ferritin level can differentiate the two anemias.

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Sideroblastic Anemia

defective synthesis, leading to increased iron stores, high serum iron and transferrin saturation, drug induced corrected

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Vitamin B12 and Folate Deficiency

Low B12 or folate: macrocytosis is common but not sensitive. Serum and RBC folate and methylmalonic acid and homocysteine

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Chronic Lymphocytic Leukemia (CLL)?

Most is incidental, indolent, affects older men, impacts bone marrow, liver, and nodes and it is staged via tumor burden.

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Multiple Myeloma in Elderly?

Classic symptoms include marrow plasmacytosis, lytic bone lesions and antibody spike in the urine, consider treatment for hypercalcemia

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Polycythemia Vera

A marrow disorder that results in increased RBC, leukocytosis, thrombocytosis, with genetic cause, treat via phlebotomy.

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Cancer in the Elderly?

Cancer most significant risk is age, it behaves differently in the old

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Cancer Screening

Discuss life expectancy, screening impacts quality life

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USPSTF Screening Age?

USPSTF recommends biennial screening mammography for women aged 50 to 74 years

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Lung Cancer Screening in Elderly?

Screen between 50 and 80, those over 65 or those within 15 years of smoking quitting

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Prostate Cancer Screening?

Over 75 years of age stop screening with PSA test screening

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Atypical Pneumonia in Geriatrics

Pneumonia can occur without typical symptoms like fever in older adults.

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Urinary Tract Infection (UTI) in Elderly

A common condition in older adults that often presents with atypical symptoms like confusion and functional decline instead of typical urinary symptoms.

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Pneumonia Diagnosis in Elderly

Pulse oximetry is the first step to detect hypoxemia, then CXR if respiratory distress is present.

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Anemia of Chronic Disease (ACD)

Common in elderly due to chronic illnesses, presenting as low serum iron, low transferrin saturation, and elevated ferritin.

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Vitamin B12 Deficiency Symptoms

B12 deficiency often elevates methylmalonic acid and homocysteine, causing fatigue, numbness, and anemia.

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Non-Hodgkin Lymphoma

Non-Hodgkin lymphoma may cause anemia, low platelets, high lymphocytes, positive Coombs test, systemic symptoms, and Raynaud's.

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Clostridium difficile Colitis

Clostridium difficile infection should be suspected, leading to diagnostics like colonoscopy to look for hyperemic mucosa.

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Skin Cancer Screening Unnecessary

USPSTF does NOT recommend routine skin cancer screening due to lack of evidence reducing morbidity or mortality.

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Iron Deficiency Anemia Treatment

Fatigue, angular cheilitis, glossitis, anemia, and low ferritin indicate iron deficiency. Start oral iron, investigate the cause.

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Catheter-Associated UTIs

Catheter-associated UTIs require immediate urinalysis with culture for symptoms like fever, chills, or delirium.

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Vitamin B12 Deficiency Treatment

Vitamin B12 deficiency presents with neurological and hematological symptoms. requires lifelong B12 injections

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B12 Deficiency Diagnostic Marker

Serum MMA and homocysteine levels are elevated in B12 deficiency.

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Allopurinol Use in Polycythemia Vera

Allopurinol prevents hyperuricemia associated with increased cell turnover in polycythemia vera.

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Rouleaux Formation in Myeloma

Rouleaux formation supports multiple myeloma diagnosis, associated with anemia, bone pain, and hypercalcemia.

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Annual Influenza Vaccination in Elderly

USPSTF recommends annual influenza vaccine strongly for all adults aged 65 and older to reduce morbidity and mortality.

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Lung Cancer Screening Criteria

Screen for lung cancer ages 50-80 with >=30 pack year

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Study Notes

  • Iron deficiency anemia presents with low ferritin; initial treatment is oral iron and further evaluation to determine underlying cause (GI blood loss).
  • Catheter-associated UTIs in elderly with indwelling catheters require immediate urinalysis with culture for symptoms such as fever, chills, or delirium.
  • Vitamin B12 deficiency presents with neurological symptoms and elevated methylmalonic acid levels; lifelong monthly IM injections required, especially in pernicious anemia.
  • Allopurinol indicated in polycythemia vera to prevent hyperuricemia associated with increased cell turnover.
  • Multiple myeloma is characterized by rouleaux formation of RBCs, monoclonal spike, bone pain, anemia, hypercalcemia, and recurrent infections.
  • Septic arthritis in elderly frequently caused by Staphylococcus aureus or gram-negative bacilli, unlike younger adults where gonococcal arthritis is common.
  • Herpes zoster vaccine reduces incidence of shingles by ~50% and postherpetic neuralgia by 66%.
  • Iron deficiency anemia presents with fatigue, pallor, syncope, exertional dyspnea, low ferritin, high TIBC, and low serum iron.
  • Antibiotic-associated diarrhea and colitis with fever, abdominal pain in elderly indicates C. difficile infection; stool assay confirms diagnosis.
  • USPSTF recommends mammography screening every 2 years for women ages 50-74.
  • USPSTF recommends against PSA screening in men ≥75 years due to low benefit and potential harm.
  • Colonoscopy every 10 years recommended by USPSTF from ages 50–75 for colorectal cancer screening.
  • USPSTF recommends annual low-dose chest CT screening for adults aged 50-80 with ≥30 pack-year smoking history, including those who quit within the past 15 years.
  • Cervical cancer screening (Pap smears) stops at age 65 if prior screenings normal.
  • USPSTF advises against routine ovarian cancer screening in asymptomatic women without genetic risk.
  • USPSTF does not recommend routine skin cancer screening due to insufficient evidence for reducing mortality.
  • USPSTF recommends discontinuation of routine colorectal cancer screening after age 75 if prior screens are normal.
  • Annual influenza vaccine strongly recommended for all adults aged 65 and older to reduce morbidity and mortality.

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