NIH 2 Final prep
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Questions and Answers

What is the primary route of transmission for the Ebola virus?

  • Vector-borne
  • Direct contact (correct)
  • Contaminated water
  • Aerosol droplets

What is the recommended minimal time for effective hand washing?

  • 20 seconds (correct)
  • 10 seconds
  • 30 seconds
  • 15 seconds

In what type of asepsis technique is a sterile environment required?

  • Surgical procedures (correct)
  • Injections
  • Wound cleaning
  • Routine patient care

Which form of infection control involves the use of private rooms and specific attire?

<p>Transmission-based precautions (A)</p> Signup and view all the answers

Which of the following pathogens is commonly associated with healthcare-associated infections?

<p>Escherichia coli (C)</p> Signup and view all the answers

What is the purpose of using ultraviolet light in patient care areas?

<p>To disinfect surfaces (A)</p> Signup and view all the answers

Which type of bacteria requires oxygen for survival?

<p>Aerobic bacteria (B)</p> Signup and view all the answers

What is the primary characteristic of viruses?

<p>They depend on host cells to live and reproduce. (A)</p> Signup and view all the answers

Which of the following is considered a reservoir for infectious agents?

<p>Insects and animals (C)</p> Signup and view all the answers

In which mode of transmission does an infectious agent require a vector?

<p>Vector-borne (B)</p> Signup and view all the answers

What role do prions play in infections?

<p>They consist of proteins and can lead to rapid degeneration. (A)</p> Signup and view all the answers

What type of microorganism can be found in soil and has a flexible membrane?

<p>Protozoa (A)</p> Signup and view all the answers

Which disease is associated with helminths?

<p>Trichinosis (D)</p> Signup and view all the answers

What is a key prevention strategy for gastrointestinal tract infections associated with foley catheters?

<p>Strict aseptic technique (B)</p> Signup and view all the answers

Which medication is typically used to treat Methicillin-resistant staphylococcus aureus (MRSA)?

<p>Vancomycin hydrochloride (C)</p> Signup and view all the answers

Which of the following symptoms is NOT typically associated with MRSA infections?

<p>Watery stools (D)</p> Signup and view all the answers

What is an important method to prevent the spread of Vancomycin-resistant enterococci (VRE)?

<p>Proper hand hygiene (B)</p> Signup and view all the answers

What characterizes antibiotic-associated diarrhea?

<p>Involves upset of natural gut microbiota (B)</p> Signup and view all the answers

What is a common symptom of Clostridium Difficile infection?

<p>Watery stools (B)</p> Signup and view all the answers

Which treatment is NOT recommended for Clostridium Difficile infection?

<p>Antibiotic therapy for all bacterial infections (C)</p> Signup and view all the answers

What is the nursing action associated with monitoring for potential infections?

<p>Monitoring for elevated white blood cell counts (D)</p> Signup and view all the answers

What is the primary mechanism behind the symptoms observed in anaphylaxis?

<p>Mast cells releasing histamine (D)</p> Signup and view all the answers

Which of the following symptoms is least likely associated with urticaria?

<p>Severe hypotension (C)</p> Signup and view all the answers

In which situation is angioedema considered life-threatening?

<p>When involving the upper airway (B)</p> Signup and view all the answers

What is the purpose of performing skin testing in allergic reactions?

<p>To identify specific allergens (C)</p> Signup and view all the answers

What occurs during a Type II hypersensitivity reaction?

<p>Antibody-mediated destruction of cells (B)</p> Signup and view all the answers

Which blood type is considered a universal donor?

<p>Type O (A)</p> Signup and view all the answers

What is a common source of urticaria?

<p>Medications (C)</p> Signup and view all the answers

What is the primary reason for transplant rejection?

<p>Transplanted tissue being recognized as foreign (D)</p> Signup and view all the answers

What condition is characterized by antibodies against gastric parietal cells and intrinsic factor?

<p>Pernicious anemia (C)</p> Signup and view all the answers

Which therapeutic measure is NOT typically used for idiopathic autoimmune hemolytic anemia?

<p>Dietary restrictions (D)</p> Signup and view all the answers

What is a common complication following transplant surgery?

<p>Total failure and loss of transplanted organ (A)</p> Signup and view all the answers

Which symptom is associated with pernicious anemia?

<p>Peripheral neuropathy (A)</p> Signup and view all the answers

What can happen if agglutination occurs in idiopathic autoimmune hemolytic anemia?

<p>Tissue ischemia due to blood vessel occlusions (B)</p> Signup and view all the answers

What is a common therapeutic measure for managing transplant rejection?

<p>Lifelong immunosuppressive therapy (A)</p> Signup and view all the answers

Hashimoto Thyroiditis leads to which ultimate thyroid condition?

<p>Hypothyroidism (B)</p> Signup and view all the answers

What is the primary therapeutic measure for patients who have received incompatible blood?

<p>Prevention and administration of Rhogam (A)</p> Signup and view all the answers

What type of hypersensitivity reaction is characterized by immune complexes leading to blood vessel damage?

<p>Type III hypersensitivity (A)</p> Signup and view all the answers

Which of the following symptoms is NOT associated with serum sickness?

<p>Immediate allergic reaction (A)</p> Signup and view all the answers

How should a nurse respond if an allergic reaction occurs during a blood transfusion?

<p>Stop the transfusion and flush with normal saline (B)</p> Signup and view all the answers

What is the typical time frame for symptoms to develop in serum sickness after exposure to penicillin or sulfonamide?

<p>7-10 days (A)</p> Signup and view all the answers

What cell type is primarily involved in a Type IV hypersensitivity reaction?

<p>T lymphocytes (D)</p> Signup and view all the answers

Which substance is NOT a potential cause of contact dermatitis?

<p>Penicillin (D)</p> Signup and view all the answers

Which of the following complications is common in patients allergic to latex?

<p>Allergy to tomatoes (D)</p> Signup and view all the answers

Which of the following is a subjective symptom of liver dysfunction?

<p>Abdominal pain (A)</p> Signup and view all the answers

What is one of the signs of liver transplant rejection?

<p>Heart rate greater than 100 bpm (D)</p> Signup and view all the answers

Which of the following factors is NOT a risk factor for liver cancer?

<p>Genetic predisposition (C)</p> Signup and view all the answers

Which diagnostic test is commonly used to show tumor growth in patients with liver issues?

<p>MRI or CT scan (D)</p> Signup and view all the answers

What therapeutic intervention is used for treating liver cancer by injecting drugs directly into the affected area?

<p>Chemotherapy drugs by injection into the hepatic artery (A)</p> Signup and view all the answers

What is the most common cause of constipation related to medications?

<p>Narcotics (B)</p> Signup and view all the answers

Which of the following is NOT a sign or symptom of diarrhea?

<p>Increased appetite (D)</p> Signup and view all the answers

Which dietary choice is most recommended to prevent constipation?

<p>High fiber diet (D)</p> Signup and view all the answers

Which complication is specifically linked to prolonged constipation?

<p>Impaction (A)</p> Signup and view all the answers

Which of the following is a key indicator of dehydration in patients with diarrhea?

<p>Decreased skin turgor (A)</p> Signup and view all the answers

What is the purpose of using full-strength formula for enteral feeds?

<p>To decrease contamination risk (D)</p> Signup and view all the answers

Which electrolyte imbalance is a significant concern for older adults experiencing diarrhea?

<p>Hypokalemia (B)</p> Signup and view all the answers

What is the main preventive measure against infections during enteral feeding?

<p>Proper food handling and hygiene (D)</p> Signup and view all the answers

What is a common symptom associated with Crohn's Disease?

<p>Frequent diarrhea that may contain blood (C)</p> Signup and view all the answers

Which of the following risk factors is commonly associated with chronic constipation?

<p>Sedentary lifestyle (D)</p> Signup and view all the answers

Which diagnostic test can be used to evaluate Crohn's Disease?

<p>CT scan (B), Barium enema (C)</p> Signup and view all the answers

What complication can arise from ulcerative colitis?

<p>Colorectal cancer (C)</p> Signup and view all the answers

What therapeutic approach is recommended for home treatment of mild diverticulosis?

<p>Over-the-counter pain medications and liquid diet (B)</p> Signup and view all the answers

Which symptom is NOT typically associated with Crohn's Disease?

<p>Chronic constipation (B)</p> Signup and view all the answers

What is the most common reason for the development of acute pancreatitis?

<p>Heavy alcohol consumption (C)</p> Signup and view all the answers

What is one of the main concerns when managing a patient with Crohn's Disease?

<p>Preventing malnutrition (A)</p> Signup and view all the answers

Which sign indicates severe acute pancreatitis and involves discoloration around the umbilicus?

<p>Cullen's Sign (B)</p> Signup and view all the answers

Which demographic is more commonly affected by Crohn's Disease?

<p>Women under 30 (C), Caucasians (D)</p> Signup and view all the answers

What diagnostic test result is used to confirm acute pancreatitis?

<p>Serum amylase &gt; 3 times normal (A)</p> Signup and view all the answers

Which complication is least likely to occur with acute pancreatitis?

<p>Diabetes mellitus (D)</p> Signup and view all the answers

In chronic pancreatitis, what is the main consequence affecting pancreatic function?

<p>Exocrine insufficiency (C)</p> Signup and view all the answers

What is one of the therapeutic interventions recommended for severe acute pancreatitis?

<p>Aggressive IV fluids (C)</p> Signup and view all the answers

Which of the following symptoms is characteristic of acute pancreatitis?

<p>Low grade fever (D)</p> Signup and view all the answers

Which condition is most likely to cause obstruction in chronic pancreatitis?

<p>Gallstones (C)</p> Signup and view all the answers

Which stage of hepatitis is characterized by jaundice and worsening symptoms?

<p>Icteric stage (C)</p> Signup and view all the answers

What role do direct-acting antiviral medications play in hepatitis treatment?

<p>Target specific genotypes for HCV therapy (B)</p> Signup and view all the answers

Which nursing diagnosis is related to liver enlargement and requires pain management interventions?

<p>Acute pain (C)</p> Signup and view all the answers

What should be avoided to prevent further liver damage in patients with liver issues?

<p>Herbal supplements and alcohol (B)</p> Signup and view all the answers

Which diagnostic test is considered essential for assessing liver conditions?

<p>Liver biopsy (B)</p> Signup and view all the answers

What is a common symptom during the prodromal stage of hepatitis?

<p>Flu-like symptoms (A)</p> Signup and view all the answers

What is the primary purpose of administering antivirals in HBV treatment?

<p>Prevent cirrhosis and liver damage (A)</p> Signup and view all the answers

Which of the following statements about hepatitis complications is true?

<p>Carriers of the virus are at risk for developing liver cancer. (B)</p> Signup and view all the answers

What is a common sign or symptom of pancreatic disease?

<p>Steatorrhea (greasy, foul-smelling stools) (B)</p> Signup and view all the answers

Which of the following is a known risk factor for ductal adenocarcinoma of the exocrine pancreas?

<p>Chronic pancreatitis (D)</p> Signup and view all the answers

What is a recommended prevention strategy for pancreatic disease?

<p>Smoking cessation (C)</p> Signup and view all the answers

Which diagnostic test is primarily used to assess pancreatic health?

<p>CT and MRI scans (B)</p> Signup and view all the answers

What complication may develop from cysts filled with pancreatic enzymes?

<p>Abscess and fistulas (C)</p> Signup and view all the answers

Which symptom is most likely to indicate advanced pancreatic cancer?

<p>Severe pruritus (itching) (C)</p> Signup and view all the answers

Which therapeutic intervention is crucial for managing pancreatitis?

<p>Stop alcohol use (C)</p> Signup and view all the answers

What is a common postoperative complication associated with pancreatic surgery?

<p>Thrombophlebitis (A)</p> Signup and view all the answers

What type of meals is recommended for individuals with pancreatic conditions?

<p>Small, low-fat meals (C)</p> Signup and view all the answers

Which test is NOT typically used in the diagnosis of pancreatitis?

<p>White blood cell count (A)</p> Signup and view all the answers

Which of these are needed for aerobic bacteria to reproduce?

<p>Oxygen (A)</p> Signup and view all the answers

Which of these are examples of a vector for infection?

<p>Mosquitoes (D)</p> Signup and view all the answers

The upper respiratory tract is lined with hair-like structures called cilia.

<p>True (A)</p> Signup and view all the answers

Inflammatory exudate is released during the first stage of the inflammatory response.

<p>False (B)</p> Signup and view all the answers

Which of the following is an example of a gram-positive bacteria?

<p>Clostridium difficile (B), Staphylococcus aureus (D)</p> Signup and view all the answers

Which type of immune response is characterized by the production of antibodies?

<p>Humoral immunity (C)</p> Signup and view all the answers

Which of the following is NOT a way to prevent the spread of infection?

<p>Sharing a toothbrush (C)</p> Signup and view all the answers

Which of these are considered to be a contact precaution?

<p>C. Diff (B), MRSA (C)</p> Signup and view all the answers

What is the primary method for preventing antibiotic-associated diarrhea?

<p>Stopping the antibiotic.</p> Signup and view all the answers

Which of the following is NOT a sign or symptom of a possible infection?

<p>Hypothermia (A)</p> Signup and view all the answers

The Epstein-Barr virus, which causes infectious mononucleosis, can be spread through kissing.

<p>True (A)</p> Signup and view all the answers

Type I hypersensitivity reactions are mediated by IgE antibodies.

<p>True (A)</p> Signup and view all the answers

Which type of hypersensitivity reaction involves the destruction of cells or substances that have antigens attached to their cell membranes?

<p>Type II (B)</p> Signup and view all the answers

Which type of hypersensitivity reaction is triggered by contact with substances like poison ivy, poison oak, and latex?

<p>Type IV (B)</p> Signup and view all the answers

Autoimmune disorders occur when the immune system mistakenly attacks the body's own tissues.

<p>True (A)</p> Signup and view all the answers

HIV is a retrovirus that only has ribonucleic acid (RNA).

<p>True (A)</p> Signup and view all the answers

What is the main difference between HIV and AIDS?

<p>HIV is a chronic infection and can be managed with medication, while AIDS is a final stage of infection that is fatal (D)</p> Signup and view all the answers

AIDS wasting syndrome involves a loss of more than 10% of body weight accompanied by chronic diarrhea or fever lasting longer than 30 days.

<p>True (A)</p> Signup and view all the answers

Which of these options are correct for a patient who may have a susceptible host for infection? (Select all that apply)

<p>They may be immunocompromised. (A), They may be malnourished. (B), They may be very young or very old. (C), They may have invasive procedures. (D)</p> Signup and view all the answers

The first line of defense for the human body and the most important is the skin and mucous membranes.

<p>True (A)</p> Signup and view all the answers

If you are washing your hands using soap and water, you should only lather for 10 seconds.

<p>False (B)</p> Signup and view all the answers

Which type of precautions are used for patients with an infection that can be spread through blood, body fluids, and body substances?

<p>Standard Precautions (C)</p> Signup and view all the answers

It is not necessary to remove a Foley catheter unless it is causing problems.

<p>False (B)</p> Signup and view all the answers

Antibiotic-associated diarrhea is only caused by ampicillin.

<p>False (B)</p> Signup and view all the answers

What is a sign that might indicate a patient has septic shock?

<p>Decrease in blood pressure.</p> Signup and view all the answers

What type of virus causes Infectious Mononucleosis?

<p>Epstein-Barr virus</p> Signup and view all the answers

Zika virus is usually spread through direct contact with an infected person.

<p>False (B)</p> Signup and view all the answers

What are the possible complications of Ebola? (Select all that apply)

<p>Joint problems. (A), Vision Problems. (B)</p> Signup and view all the answers

Which type of asepsis should be used with surgery and other invasive procedures?

<p>Sterile technique (A)</p> Signup and view all the answers

What is the most common HAI (health-care associated infection) in the United States?

<p>Gastrointestinal tract infection (A)</p> Signup and view all the answers

It is okay to share a toilet at home with someone that has a vancomycin-resistant enterococci (VRE) infection.

<p>False (B)</p> Signup and view all the answers

After stopping an antibiotic, diarrhea is usually not a concern.

<p>False (B)</p> Signup and view all the answers

It is not necessary to monitor a patient's peak and trough levels if they're on vancomycin.

<p>False (B)</p> Signup and view all the answers

What is the primary function of the lymphatic system?

<p>Destroy foreign substances and microbes. (B)</p> Signup and view all the answers

The B cells are involved in both the humoral and cell-mediated immune response.

<p>False (B)</p> Signup and view all the answers

It is not necessary to teach a patient about always carrying an epinephrine autoinjector if they have a severe allergy.

<p>False (B)</p> Signup and view all the answers

Which type of hypersensitivity reaction is most common?

<p>Type I (A)</p> Signup and view all the answers

Anaphylaxis is a mild reaction that often occurs as a result of a bee sting.

<p>False (B)</p> Signup and view all the answers

It is okay to use a nasal decongestant without talking to your doctor about it.

<p>False (B)</p> Signup and view all the answers

Atopic dermatitis is caused by an antibody deficiency.

<p>False (B)</p> Signup and view all the answers

Urticaria is commonly caused by a viral infection.

<p>False (B)</p> Signup and view all the answers

Angioedema is a life-threatening reaction if it involves a blood vessel that is in the upper airway.

<p>True (A)</p> Signup and view all the answers

Patients with blood type O are universal recipients.

<p>False (B)</p> Signup and view all the answers

The Rhogam injection is given to all mothers during labor and delivery.

<p>False (B)</p> Signup and view all the answers

A Type III hypersensitivity reaction is a cell-mediated immune response.

<p>False (B)</p> Signup and view all the answers

Serum sickness is a severe, chronic condition that affects the immune system.

<p>False (B)</p> Signup and view all the answers

Contact dermatitis can only be triggered by soap.

<p>False (B)</p> Signup and view all the answers

The majority of people who have a transplant will experience a transplant rejection.

<p>False (B)</p> Signup and view all the answers

Patients who have pernicious anemia cannot absorb vitamin B12 from supplements.

<p>False (B)</p> Signup and view all the answers

The most common symptom of Hashimoto thyroiditis is a goiter (enlargement of the thyroid gland).

<p>True (A)</p> Signup and view all the answers

Discoid lupus erythematosus (DLE) is the most common form of lupus erythematosus.

<p>False (B)</p> Signup and view all the answers

Patients who have ankylosing spondylitis are at a high risk for developing serious infections.

<p>False (B)</p> Signup and view all the answers

Which of the following are considered treatments for hypogammaglobulinemia? (Select all that apply)

<p>Immunoglobulin injections (A), Fresh frozen plasma (B)</p> Signup and view all the answers

HIV is a retrovirus that can only be acquired through sexual intercourse.

<p>False (B)</p> Signup and view all the answers

There is a cure for AIDS.

<p>False (B)</p> Signup and view all the answers

AIDS wasting syndrome is a serious condition that can lead to death.

<p>True (A)</p> Signup and view all the answers

The most common opportunistic infections that affect people with AIDS are tuberculosis, pneumocystis pneumonia, and cytomegalovirus.

<p>True (A)</p> Signup and view all the answers

The CD4 T lymphocyte count is a test is used to determine how much HIV is in the blood.

<p>False (B)</p> Signup and view all the answers

It is not necessary to adjust the antiretroviral therapy for a patient who has HIV depending on their stage of the disease.

<p>False (B)</p> Signup and view all the answers

The primary goal of treating a patient who has HIV is to prevent or delay opportunistic infections.

<p>True (A)</p> Signup and view all the answers

A common nursing diagnosis used in a patient who has HIV is ineffective protection.

<p>True (A)</p> Signup and view all the answers

It is not possible to determine how much HIV is in a patient's blood without a diagnosis of AIDS.

<p>False (B)</p> Signup and view all the answers

HIV is classified as both a chronic and a retrovirus.

<p>True (A)</p> Signup and view all the answers

Flashcards

Ebola Transmission

Ebola is spread through direct contact with infected bodily fluids, such as blood, vomit, and feces. It is not spread through the air.

Ebola Symptoms

Symptoms of Ebola typically appear within 2 to 21 days after exposure and include fever, headache, diarrhea, vomiting, abdominal pain, muscle pain, unexplained bruising, and bleeding.

Zika Virus Transmission

Zika virus is primarily transmitted through the bite of an infected Aedes mosquito.

Zika Virus Symptoms

Common symptoms of Zika virus include fever, headache, rash, muscle and joint pain, and conjunctivitis (red eyes).

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Healthcare-Associated Infection (HAI)

An infection acquired during a stay in a healthcare facility, such as a hospital or nursing home.

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Hand Hygiene in Healthcare

Washing hands with soap and water for at least 20 seconds is crucial in healthcare settings. This includes before and after patient contact, and always after glove use.

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Medical Asepsis

A clean technique used to reduce the number of pathogens. This includes practices like hand hygiene and using clean equipment.

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Surgical Asepsis

A sterile technique used to ensure an area is free of microorganisms and spores. This is used in surgery and sterilization.

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Microbiota

Microbes that naturally live in a body part.

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Pathogen

A microbe that causes disease.

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Aerobic Bacteria

Bacteria that need oxygen to survive. Found on the skin.

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Anaerobic Bacteria

Bacteria that can live without oxygen. Found in the GI tract.

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Virus

Smaller than bacteria, they rely on host cells to survive and reproduce. Antiviral drugs only reduce symptoms.

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Reservoir

The natural environment where an infectious agent lives.

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Portal of Exit

The path an infectious agent uses to leave its reservoir.

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Direct Transmission

Direct contact or droplet spread through touching, kissing, or sex.

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HAI

Healthcare-associated infection, an infection acquired during a healthcare setting. This can include things like hospitals, clinics, nursing homes, and doctor's offices.

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VAP

Ventilator-associated pneumonia, a type of pneumonia that develops in a person who is using a mechanical ventilator.

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How to Prevent HAIs

Preventing HAIs involves practicing good hand hygiene, using sterile techniques, and isolating patients with infections.

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MRSA

Methicillin-resistant Staphylococcus aureus: a type of bacteria that is resistant to many common antibiotics. It can cause skin infections, pneumonia, and bloodstream infections.

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Clostridium Difficile

A type of bacteria that causes severe diarrhea and inflammation of the colon. It often occurs after antibiotic use.

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Antibiotic-associated diarrhea

Diarrhea that occurs as a side effect of taking antibiotics. It is caused by an imbalance of the gut bacteria.

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Peak/Trough levels

Monitoring peak and trough levels of antibiotics is crucial for ensuring effectiveness and minimizing toxicity. Peak levels measure the highest concentration of the drug in the blood after administration. Trough levels measure the lowest concentration of the drug before the next dose.

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Transplant Rejection

The body's immune system attacks the transplanted tissue or organ, seeing it as foreign. This can lead to organ failure and death.

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Immunosuppression Therapy

Medications used to suppress the immune system after an organ transplant to prevent rejection.

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Pernicious Anemia

A type of anemia caused by the body's inability to absorb vitamin B12 due to antibodies attacking the stomach lining.

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Hashimoto Thyroiditis

An autoimmune disorder affecting the thyroid gland. It initially causes hyperthyroidism followed by hypothyroidism.

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Direct Antiglobulin Test (Coombs Test)

A blood test that helps diagnose autoimmune hemolytic anemia. Detects antibodies attached to red blood cells.

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Autoimmune Disorder

A condition where the immune system mistakenly attacks the body's own tissues and organs.

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Autoantibodies

Antibodies produced by the immune system that attack the body's own tissues or organs.

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Idiopathic Autoimmune Hemolytic Anemia

A blood disorder caused by the immune system destroying red blood cells.

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Anaphylaxis

A severe, life-threatening allergic reaction. It occurs when the body releases a large amount of histamine and other chemicals in response to an allergen. This can cause widespread inflammation, swelling, and a drop in blood pressure.

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What are the signs and symptoms of anaphylaxis?

Symptoms include: difficulty breathing, wheezing, swelling of the face, lips, and tongue, hives, skin rashes, and a drop in blood pressure. In severe cases, it can lead to unconsciousness and even death.

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What are some treatments for anaphylaxis?

Treatment involves administering epinephrine (adrenaline) to constrict blood vessels and open airways, as well as oxygen, IV fluids, and antihistamines to reduce inflammation.

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Urticaria

A common skin reaction characterized by raised, itchy welts called hives. It can be triggered by allergies, medications, or even stress.

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Angioedema

A type of allergic reaction that causes swelling beneath the skin. It is often associated with urticaria but can also occur independently.

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What is a hemolytic transfusion reaction?

Occurs when incompatible blood types are mixed, leading to the destruction of red blood cells (RBCs). The body recognizes the foreign RBC antigens as threats and attacks them, causing blood vessel blockage and potentially organ damage.

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Type II Hypersensitivity Reactions

Involve the destruction of a cell or substance by antibodies attaching to a cell membrane. The antibody-antigen complex triggers the immune system to attack the targeted cell, leading to its destruction.

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What are universal donors and recipients?

Universal donors have type O blood and can donate to anyone, while universal recipients have type AB blood and can receive blood from anyone.

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What is a type II hypersensitivity reaction?

A type II hypersensitivity reaction, also known as cytotoxic hypersensitivity, involves the destruction of cells by antibodies. This occurs when antibodies bind to antigens on the surface of cells, triggering the complement system and phagocytosis, ultimately leading to cell lysis.

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What is a type III hypersensitivity reaction?

Type III hypersensitivity reaction, also known as immune complex-mediated hypersensitivity, results from the formation of immune complexes between antigens and antibodies. These complexes deposit in blood vessel walls, triggering inflammation and tissue damage.

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What is a type IV hypersensitivity reaction?

Type IV hypersensitivity reaction, also known as delayed-type hypersensitivity, is a cell-mediated response involving T lymphocytes. Sensitized T cells encounter antigens and release cytokines, leading to inflammation and tissue damage.

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What is Rhogam?

Rhogam is an injection of Rh immunoglobulin given to Rh-negative mothers to prevent sensitization to the Rh factor from their Rh-positive fetus. It prevents the development of antibodies that can harm future Rh-positive pregnancies.

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Contact Dermatitis

A type IV hypersensitivity reaction that occurs when skin comes into contact with allergens like poison ivy, poison oak, or latex. The allergen triggers an immune response, leading to inflammation, itching, and redness.

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Serum Sickness

A rare type III hypersensitivity reaction that occurs 7-10 days after exposure to certain medications, like penicillin or sulfonamides. Immune complexes form in blood vessels, causing inflammation, fever, rash, and joint pain.

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What are the therapeutic measures for type II hypersensitivity reactions?

Therapeutic measures for type II hypersensitivity reactions focus on prevention, such as avoiding exposure to the triggering antigen. Treatment may include antihistamines, corticosteroids, and sympathomimetics to manage symptoms.

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What are the therapeutic measures for type III hypersensitivity reactions?

Therapeutic measures for type III hypersensitivity reactions include antipyretics, analgesics, and anti-inflammatories to manage symptoms like fever, pain, and inflammation. Antihistamines may also be used for urticaria.

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Constipation

Hard, dry stools due to increased water absorption in the intestines.

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Causes of Constipation

Medications (narcotics, tranquilizers), hemorrhoids, fissures, low fiber intake, dehydration.

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Complications of Constipation

Hemorrhoids, fecal impaction, ulcers, straining, megacolon.

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Diarrhea

Frequent, watery stools due to decreased water absorption and nutrient absorption.

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Causes of Diarrhea

Bacterial or viral infection, food allergies.

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Dehydration with Diarrhea

Diarrhea causes loss of fluids and electrolytes, leading to dehydration.

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Hypokalemia

Low potassium levels in the blood, potentially causing fatigue, weakness, and heart problems.

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Geriatric Consideration for Diarrhea

Older individuals are more susceptible to dehydration and hypokalemia due to diarrhea.

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Hepatitis B Transmission

Hepatitis B is spread primarily through contact with infected blood, such as through sharing needles, sexual contact, or from mother to baby during childbirth.

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Hepatitis A Symptoms

Hepatitis A symptoms include jaundice (yellowing of the skin and eyes), fatigue, abdominal pain, loss of appetite, nausea, and dark urine.

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Hepatitis C Chronic Infection

Hepatitis C infection can become chronic, leading to long-term liver damage, cirrhosis, and liver cancer.

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Hepatitis B Treatment

Treatment for chronic hepatitis B infection includes antiviral medications like pegylated interferon therapy and tenofovir.

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Hepatitis Complications

Hepatitis can lead to complications like liver failure, fulminant hepatitis (sudden and severe), and chronic liver disease.

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Hepatitis Testing

Diagnostic testing for hepatitis includes liver biopsy, serum testing for liver enzymes, serum bilirubin, and prothrombin time.

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Hepatitis Nursing Care

Nursing care for hepatitis patients focuses on pain management, nutritional support, and education on lifestyle modifications.

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Hepatitis Prevention

Prevention of hepatitis includes vaccination for HAV and HBV, practicing safe sex, and avoiding contact with infected blood.

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Liver Dysfunction Symptoms

Subjective signs of liver issues include abdominal pain, loss of appetite, nausea, and severe itching.

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Liver Transplant Candidates

Patients with end-stage liver failure, hepatitis, biliary disease, metabolic disorders, hepatic vein obstruction are potential candidates for a liver transplant.

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Liver Transplant Rejection Signs

Signs of transplant rejection include a pulse over 100 bpm, temperature over 101 degrees, right upper quadrant pain, and jaundice.

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Liver Cancer Risk Factors

Chronic hepatitis B or C, nutritional deficiencies, and exposure to liver toxins increase the risk of liver cancer.

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Liver Cancer Diagnosis

Liver cancer is diagnosed using blood tests (ALP), imaging scans (MRI, CT), and biopsies.

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Diverticulosis

A condition where small, bulging pouches form in the lining of the colon. It's usually asymptomatic but can cause pain, bloating, and bleeding.

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Diverticulosis Risk Factors

Factors that increase your chances of developing diverticulosis include low-fiber diets, high animal fat intake, obesity, lack of physical activity, smoking, and certain medications.

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Crohn's Disease

An inflammatory bowel disease that affects the digestive tract, causing inflammation in patches throughout the intestines. It's an autoimmune disease.

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Crohn's Disease Symptoms

Symptoms of Crohn's disease include abdominal pain, diarrhea (sometimes bloody), weight loss, fatigue, mouth sores, and electrolyte imbalance.

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Ulcerative Colitis

Another inflammatory bowel disease, but this one mainly affects the large intestine and rectum. It causes ulcers and inflammation in the lining of the colon.

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Ulcerative Colitis Complications

Complications of ulcerative colitis include malnutrition, obstruction, fissures, abscesses, fistulas, perforation, and bleeding.

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IBD Treatment

Treatment for both Crohn's and Ulcerative Colitis usually includes medication to reduce inflammation and manage symptoms, dietary changes, and sometimes surgery.

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IBD Nursing Knowledge

Nurses caring for patients with IBD need to monitor vital signs, abdominal distention, signs of sepsis, blood pressure, heart rate, and urine output.

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Acute Pancreatitis

Inflammation of the pancreas caused by autodigestion, often due to heavy alcohol use or gallstones. It leads to severe pain, fluid loss, and potentially organ failure.

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Epigastric Pain

Pain in the upper central abdomen, often radiating to the back and flanks, a characteristic symptom of acute pancreatitis.

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Board-like Abdomen

A rigid, hard abdomen, indicating severe inflammation and muscle spasms typically seen in acute pancreatitis.

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Turner Sign

A purplish discoloration of the flanks, a sign of hemorrhagic pancreatitis.

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Cullen Sign

A purplish discoloration around the umbilicus, indicating hemorrhagic pancreatitis.

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Chronic Pancreatitis

A progressive inflammatory disease of the pancreas, causing duct obstruction, tissue death, and eventually, exocrine and endocrine insufficiencies.

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Exocrine Pancreatic Insufficiency

A condition in which the pancreas does not produce enough digestive enzymes, affecting nutrient absorption.

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Endocrine Pancreatic Insufficiency

A condition where the pancreas doesn't produce enough insulin, leading to diabetes mellitus.

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Causes of Chronic Pancreatitis

Common causes include alcohol abuse, smoking, obstructive biliary disease (blockage in the bile duct), and genetic predisposition.

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Symptoms of Chronic Pancreatitis

Many people are asymptomatic, but common symptoms include epigastric pain (upper abdominal pain) that worsens after eating, nausea, vomiting, and weight loss.

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Ductal Adenocarcinoma of Exocrine Pancreas

A type of pancreatic cancer that starts in the ducts of the exocrine pancreas. It's a highly aggressive cancer with a poor prognosis.

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Risk Factors for Pancreatic Cancer

Smoking, obesity, diabetes mellitus, chronic pancreatitis, and exposure to certain chemicals are all major risk factors.

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Signs and Symptoms of Pancreatic Cancer

Often discovered at a late stage, symptoms include weight loss, abdominal pain, nausea, vomiting, jaundice, and possible new onset of diabetes.

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Diagnostic Tests for Pancreatic Cancer

Blood tests for tumor markers like CA 19-9, imaging tests such as CT scans, MRIs, and endoscopies. A biopsy is needed for confirmation.

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Therapeutic Measures for Pancreatic Cancer

Surgery is the primary treatment option, often a Whipple procedure. Other treatments include chemotherapy, radiation, and stenting to relieve blockages.

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Gallbladder Disease

A broad term that covers disorders of the gallbladder and bile ducts, including gallstones and inflammation.

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Most Common Gallbladder Disorder

Gallstones and inflammation of the gallbladder and common bile duct represent the most frequent disorder.

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Blood Transfusion Priority

The most important nursing action when a client receives a blood transfusion is to monitor for reactions.

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Desquamation

Peeling or shedding of skin, often a side effect of chemotherapy.

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Informed Consent for Biopsy

Before a bone marrow aspiration, the nurse must ensure the client has given informed consent.

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Petechiae

Small, purplish hemorrhagic spots under the skin.

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Thrombocytopenia

A low platelet count in the blood, resulting in easy bruising and bleeding.

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In Situ

Localized cancer that hasn't spread to surrounding tissues.

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Normal WBC Count

A typical white blood cell count is 4,500 - 11,000 per mm3.

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Hemorrhagic Cystitis

A serious side effect of Cyclophosphamide, causing inflammation and bleeding in the bladder.

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Radiation Therapy

Radiation can shrink tumors before surgery, making the procedure safer and more effective.

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Blood Transfusion Solution

Normal saline is the only IV solution compatible with blood transfusions.

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Benign Tumor

A non-cancerous growth that doesn't invade surrounding tissues.

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Anemia

A condition where oxygen delivery to tissues is reduced due to low red blood cell count or hemoglobin.

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Blood Transfusion Reaction

A serious reaction to a blood transfusion, often characterized by fever, chills, and rapid heartbeat.

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Iron Supplement Education

Iron supplements can cause the stools to darken.

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Bone Marrow Biopsy

A bone marrow biopsy can be taken from the sternum or hip bone.

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TNM System

The TNM system is used to stage and grade cancer, representing Tumor, Node, and Metastasis.

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Blood Transfusion Time

Blood must be transfused within 4 hours of receiving it from the blood bank.

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Universal Donor

People with blood type O-negative are considered universal donors.

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Universal Recipient

People with blood type AB-positive are considered universal recipients.

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Type II Hypersensitivity

Involves destruction of a cell by antibodies attaching to its membrane.

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Type III Hypersensitivity

Involves immune complexes forming and depositing in blood vessel walls.

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Type IV Hypersensitivity

Delayed-type hypersensitivity, involving T lymphocytes and cytokine release.

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Rhogam

An injection for Rh-negative mothers to prevent Rh sensitization.

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Client's Right to Refuse Therapy

A terminally ill adult has the right to refuse further medical treatment, even if it means they could die sooner. This is part of their autonomy and right to self-determination.

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St. John's Wort Use

St. John's wort is an herbal supplement often used to treat mild to moderate depression.

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Mind-Body Therapies

Mind-body therapies focus on the connection between the mind and body to promote well-being. They involve techniques like meditation, yoga, and progressive muscle relaxation.

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Supporting Grieving Family

When a client dies, it's important to offer compassionate support to the family, allowing them to grieve and providing them with privacy and resources.

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Alternative Therapy and the Nurse's Role

A nurse's role is to respect the client's decision to try alternative therapies, even if they are not proven effective. They should not offer opinions or judgments, but rather provide accurate information and support.

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First Step for Pain Assessment

When a client reports pain, the first step is to assess the pain level and characteristics using a pain scale and asking about location, intensity, and quality.

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Pain Management Myth

A common misconception about pain is that it is a normal part of the aging process. Pain is a symptom that needs to be addressed, regardless of age.

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Respecting Client Wishes in Chronic Illness

Nurses play a crucial role in empowering clients with chronic illnesses by respecting their wishes regarding treatment, providing education about the illness, and supporting their self-management.

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Advanced Directive's Purpose

An advanced directive is a legal document that allows individuals to express their wishes for medical treatment in the event they become unable to make decisions for themselves, especially during end-of-life care.

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Pain Assessment Tools

Pain assessment tools are essential for accurately capturing a client's pain experience. Examples include the Numeric Pain Scale, the Faces Pain Scale, and the Wong-Baker FACES Pain Rating Scale.

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Subjective Data in Pain Assessment

Subjective data refers to what the client tells you about their pain. This is important for getting their perspective and understanding their experience.

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Objective Data in Pain Assessment

Objective data refers to observable signs of pain, such as facial expressions, guarding behaviors, increased heart rate or blood pressure, and changes in breathing patterns.

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Pain Management Strategies

Pain management strategies can include pharmacological approaches like analgesics, non-pharmacological methods such as heat or cold therapy, massage, relaxation techniques, and complementary approaches like acupuncture or yoga.

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Preventing Opioid-related Respiratory Depression

When using opioids for pain management, it's crucial to monitor for signs of respiratory depression, such as decreased breathing rate and shallow breathing, and promptly adjust medication dosage or consider alternative pain management options.

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Pain as a Subjective Experience

Pain is always a subjective experience, meaning it is unique to each individual. What might cause mild pain for one person could cause excruciating pain for another. It's important to respect this individual experience.

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Non-Pharmacological Pain Management

Non-pharmacological pain management focuses on techniques that don't involve medications, such as heat or cold therapy, massage, relaxation techniques, acupuncture, and cognitive-behavioral therapy (CBT).

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Client Education in Pain Management

Educating clients about their pain is important. This includes explaining the purpose of medications, potential side effects, and how to best manage their pain with different strategies.

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Pain Management Ethical Considerations

Pain management can sometimes raise ethical dilemmas. This includes balancing a client's right to adequate pain relief with concerns about drug dependence and risks of overdose, particularly with opioids.

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Pain Management in End-of-Life Care

Pain management in end-of-life care focuses on providing comfort and dignity to the dying. This requires careful assessment, accurate medication administration, and personalized care plans to address pain and other symptoms effectively.

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Pain Management: Interdisciplinary Approach

Pain management is often best addressed through an interdisciplinary team approach, involving nurses, physicians, pharmacists, physical therapists, and other specialists to provide holistic care.

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Pain Management: Cultural Considerations

Cultural beliefs and practices can influence how individuals experience and express pain. Nurses need to be sensitive to these cultural factors to provide appropriate care.

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Pain Management: Patient-Centered Approach

Pain management should be patient-centered, meaning that it is tailored to the individual's needs, preferences, and goals. This ensures that the client feels heard and their pain is addressed effectively.

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Pain Management: Holistic Approach

Holistic pain management considers the physical, emotional, social, and spiritual aspects of the client's experience. It aims to address the underlying causes of pain, promote healing, and improve quality of life.

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Pain Management: Ongoing Assessment

Pain management requires ongoing assessment because individuals' pain levels can fluctuate. This involves regular monitoring of pain levels, effectiveness of treatments, and any new or changing symptoms.

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Pain Management: Communication is Key

Open communication with the client is vital in pain management. Nurses should encourage clients to express their pain concerns and needs clearly, and provide clear explanations of treatments and options.

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Pain Management: Respecting Individual Preferences

Respecting individual preferences in pain management involves considering a client's choice of pain medications or non-pharmacological approaches, as well as their desired level of involvement in decision-making.

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Pain Management: Understanding the Biopsychosocial Model

The biopsychosocial model acknowledges that pain is influenced by biological, psychological, and social factors. Nurses need to understand these factors to provide comprehensive pain management.

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Pain Management: Empowering the Client

Empowering the client in pain management means encouraging their active involvement in their care. This includes understanding their pain, participating in decision-making, and learning self-management techniques.

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Study Notes

Infectious Agent

  • Infectious agents can be classified as microbiota (naturally occurring microbes in a body part) or pathogens (disease-causing microbes).
  • Bacteria are single-celled organisms that may depend on hosts for reproduction and survival outside of a host; examples include C. diff.
  • Aerobic bacteria need oxygen to survive, found on the skin, while anaerobic bacteria can survive without oxygen and are found in the gastrointestinal tract.
  • Rickettsiae are bacteria transmitted by vectors (living organisms). Examples include typhus, scrub typhus, rocky mountain spotted fever.
  • Viruses are smaller than bacteria and require a host cell for reproduction; treatment includes antiviral drugs.
  • Fungi consist of yeasts and molds, some which are normal flora in the body (e.g., mouth, vagina, intestines), while others are pathogenic (cause disease); treatment includes antifungals. Examples include Candida albicans.
  • Protozoa are single-celled parasitic organisms that can be found in the soil. Examples include Trichinosis.
  • Helminths are parasitic worms that can be transmitted through the consumption of raw or undercooked meat (e.g., trichinosis). Examples include tapeworms. Creutzfeldt–Jakob disease is also an example.
  • Prions are proteins found mainly in the brain and lead to rapid progression of disease. No known treatment exists.

Reservoir

  • Reservoirs are the source of the infectious agents.
  • Animate reservoirs include people, insects, animals, and plants.
  • Inanimate reservoirs include water, soil, and medical devices.

Transmission

  • Direct transmission includes direct contact (e.g., kissing, sexual contact, scabies), droplet spread (e.g., coughing, sneezing), or skin-to-skin contact. Examples include scabies, mononucleosis, pertussis, influenza, and sexually transmitted infections (STIs).
  • Indirect transmission includes vehicle-borne (e.g., blood, water, food, medical devices), vector-borne (e.g., flea, mosquito), or airborne (e.g., influenza). Examples include influenza, norovirus, hepatitis B, Ebola, and other infectious diseases.

Portal of Exit

  • The portal of exit is the path the infectious agent leaves its reservoir.
  • Examples include respiratory tract (RT), skin, mucous membranes (MM), gastrointestinal tract (GI tract), genitourinary tract (GU tract), placenta.

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Description

Explore the world of infectious agents, including bacteria, viruses, fungi, protozoa, and helminths. Understand their classifications, roles in disease, and methods of treatment. This quiz will test your knowledge on how these microbes impact health.

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