Rabies Quiz

Play an AI-generated podcast conversation about this lesson

What is the morphology of the rabies virus?

Helical nucleocapsid contained in a bullet-shaped lipoprotein envelope (correct)

Cuboidal with a rough surface

Rod-shaped with spikes on the envelope

Spherical with a smooth surface

How many glycoprotein (G) spikes does the rabies virus have?

150

100

200 (correct)

50

Which family does rhabdoviruses belong to?

Poxviridae

Herpesviridae

Rhabdoviridae (correct)

Flaviviridae

What is the classification of rhabdoviruses infecting mammals?

Genus lyssavirus and genus vesiculovirus Signup and view all the answers

Which of the following is NOT a rabies virus related virus?

Chandipur virus Signup and view all the answers

What are the dimensions of the rabies virion?

180 x 75 nm Signup and view all the answers

What type of genome does the rabies virus have?

Single stranded RNA Signup and view all the answers

What is the primary activity of the approximately 200 glycoprotein (G) spikes of the rabies virus?

Hemagglutinin activity Signup and view all the answers

What is the incubation period for rabies in humans?

1-2 months Signup and view all the answers

Which phase of the clinical spectrum of human rabies is characterized by symptoms such as nervousness, apprehension, hallucinations, and bizarre behavior?

Acute neurologic phase Signup and view all the answers

What is the pathognomonic feature of the acute neurologic phase of human rabies?

Difficulty in drinking Signup and view all the answers

In which form of rabies in dogs does the excitative or irritative stage lack?

Dumb rabies Signup and view all the answers

Which method is most commonly used for diagnosis of human rabies by demonstrating rabies virus antigens?

Rabies antigens by immunofluorescence Signup and view all the answers

What test can establish a highly specific diagnosis of rabies viral antigen within a few hours?

Demonstration of rabies virus antigen by immunofluorescence Signup and view all the answers

What is the best single test currently available for the rapid diagnosis of rabies viral antigen in infected specimens?

Demonstration of rabies virus antigen by immunofluorescence Signup and view all the answers

Which protein is the major structural protein of the rabies virus?

Membrane or matrix (M) protein Signup and view all the answers

What is the host range of the rabies virus?

All warm-blooded animals including humans Signup and view all the answers

What is the street virus?

Virus isolated from natural human or animal infection Signup and view all the answers

What is the usual mode of inoculation for growing rabies virus in chick embryos?

Into the yolk sac Signup and view all the answers

How does rabies virus travel to the central nervous system (CNS)?

By retrograde axoplasmic transport Signup and view all the answers

What is the fate of rabies patients once clinical disease is apparent?

Fatal outcome Signup and view all the answers

Which temperature and duration can inactivate the rabies virus?

$50°C for 1 hour or 60°C for 5 minutes Signup and view all the answers

What antigen elicits complement fixing antibodies but is not protective?

$Nucleocapsid protein Signup and view all the answers

Which preparation of anti rabies serum has now replaced equine antirabies serum in many countries?

Human Rabies Immune Globulin Signup and view all the answers

What is the recommended dose for human rabies immune globulin (HRIG) for passive immunization?

20 IU per kg of body weight Signup and view all the answers

At what age are injections for concentrated cell culture vaccines given to animals?

12 weeks of age Signup and view all the answers

What is the major source of rabies virus in the bite of a rabid animal?

Saliva Signup and view all the answers

What is the classic mode of transmission of rabies from animals to humans?

Saliva in bite of rabid animal Signup and view all the answers

Which form of rabies involves the vampire bat as an important host and vector?

Wild-life or sylvatic rabies Signup and view all the answers

What is the reservoir of rabies according to the text?

Wild animals Signup and view all the answers

Which method is used to detect rabies virus antigen in live animals in corneal impressions or frozen sections of skin biopsies?

Fluorescent antibody test Signup and view all the answers

What prophylaxis is indicated for persons at high risk of contact with rabies virus, such as laboratory workers handling rabies virus or with rabid animals?

Preexposure prophylaxis Signup and view all the answers

Which type of antirabic vaccine is associated with serious risk of neurological complications and has been replaced by the non-neural vaccines?

Pasteur vaccine Signup and view all the answers

What is the ideal site for vaccination for antirabies treatment?

Anterior abdominal wall Signup and view all the answers

What is the recommended dosage schedule for a full antirabies vaccination course?

7–10 daily inoculations followed by 1–2 boosters Signup and view all the answers

Which classification of exposure warrants the highest dose of antirabies vaccine?

Class III (Severe risk) Signup and view all the answers

What is the indication for giving a full five-injection course of antirabies vaccine after five years?

Exposure to infection after five years Signup and view all the answers

Which adverse reaction is NOT associated with antirabies vaccination?

High fever Signup and view all the answers

Which herpesvirus is associated with Kaposi's sarcoma?

Human herpes virus 6 Signup and view all the answers

What is the size range of a herpesvirus virion?

150-250 nm Signup and view all the answers

Which part of the cell do varicella zoster and herpes simplex viruses establish latent infections in?

Neurons Signup and view all the answers

What is the major structural protein of a herpesvirus virion?

Capsid proteins Signup and view all the answers

Which phase of infection involves the herpesviruses being bud from the nuclear membrane?

Lytic phase Signup and view all the answers

What is the approximate size of the capsid of a herpesvirus virion?

95-105 nm diameter Signup and view all the answers

Which type of infection is characterized by reactivation in herpesviruses?

Latent infection Signup and view all the answers

What do the 8nm spikes on the envelope of a herpesvirion consist of?

'Viral glycoproteins' Signup and view all the answers

In which part of the cell do herpesviruses persist indefinitely?

'Nucleus' Signup and view all the answers

Which type of herpes virus causes oropharyngeal disease and keratoconjunctivitis?

HSV-1 Signup and view all the answers

In which host condition can people with HSV infections be contagious even when they do not have skin lesions?

Immunocompromised hosts Signup and view all the answers

What is the drug of choice for antiviral chemotherapy for HSV infections?

Acyclovir Signup and view all the answers

Which age group is highly susceptible to HSV infection?

Newborns (0-6 months) Signup and view all the answers

What is the primary manifestation of Varicella-Zoster Virus infection in normal individuals?

Chickenpox Signup and view all the answers

In what form does Varicella-Zoster Virus appear in immunocompromised individuals?

Shingles Signup and view all the answers

What is the typical age range for reactivation leading to the appearance of shingles?

>40 years Signup and view all the answers

What is the mode of transmission of Varicella-Zoster Virus?

Respiratory route Signup and view all the answers

What is the treatment for herpes infections?

There is no cure for herpes, but antiviral medications can shorten and prevent outbreaks. Signup and view all the answers

What is the primary infection caused by Varicella-Zoster Virus in children?

Chickenpox Signup and view all the answers

Which virus is associated with the development of Kaposi sarcoma, a vascular tumor common in patients with AIDS?

HHV-8 Signup and view all the answers

What is the primary activity of the approximately 200 glycoprotein (G) spikes of the rabies virus?

Binding to host cells Signup and view all the answers

Which virus causes chickenpox on primary infection and shingles upon reactivation?

VZV Signup and view all the answers

What is the characteristic effect induced by human herpesviruses that can include intranuclear inclusion bodies?

Cytopathic effects Signup and view all the answers

Which virus is linked with Burkitt lymphoma of African children, nasopharyngeal carcinoma, and other lymphoproliferative disorders?

EBV Signup and view all the answers

What can trigger the reactivation of herpes simplex viruses?

Physical trauma Signup and view all the answers

Which virus replicates in epithelial cells of the respiratory tract, salivary glands, and kidneys, and causes an infectious mononucleosis?

CMV Signup and view all the answers

What is the common clinical manifestation of type 1 herpes simplex virus (HSV-1)?

Fever blisters Signup and view all the answers

Where does the latency of herpes simplex viruses occur mainly in normal humans?

Trigeminal ganglia Signup and view all the answers

Which virus infects T lymphocytes and causes exanthem subitum (roseola infantum) in early infancy?

HHV-6 Signup and view all the answers

Which characteristic is true for herpesviruses?

Migrate up the nerves to the sensory ganglia during the primary infection Signup and view all the answers

What is the morphology of all Herpesviruses?

Icosahedral core surrounded by a protein envelope Signup and view all the answers

Which virus is associated with causing Kaposi sarcoma?

Human herpesvirus 8 Signup and view all the answers

What is the primary target cell for Human herpesvirus 1?

Mucoepithelial cells Signup and view all the answers

How do herpesviruses differ from other nuclear DNA viruses?

They encode a large number of enzymes involved in DNA synthesis Signup and view all the answers

Rabies Quiz

Podcast Beta

Questions and Answers

What is the morphology of the rabies virus?

How many glycoprotein (G) spikes does the rabies virus have?

Which family does rhabdoviruses belong to?

What is the classification of rhabdoviruses infecting mammals?

Which of the following is NOT a rabies virus related virus?

What are the dimensions of the rabies virion?

What type of genome does the rabies virus have?

What is the primary activity of the approximately 200 glycoprotein (G) spikes of the rabies virus?

What is the incubation period for rabies in humans?

Which phase of the clinical spectrum of human rabies is characterized by symptoms such as nervousness, apprehension, hallucinations, and bizarre behavior?

What is the pathognomonic feature of the acute neurologic phase of human rabies?

In which form of rabies in dogs does the excitative or irritative stage lack?

Which method is most commonly used for diagnosis of human rabies by demonstrating rabies virus antigens?

What test can establish a highly specific diagnosis of rabies viral antigen within a few hours?

What is the best single test currently available for the rapid diagnosis of rabies viral antigen in infected specimens?

Which protein is the major structural protein of the rabies virus?

What is the host range of the rabies virus?

What is the street virus?

What is the usual mode of inoculation for growing rabies virus in chick embryos?

How does rabies virus travel to the central nervous system (CNS)?

What is the fate of rabies patients once clinical disease is apparent?

Which temperature and duration can inactivate the rabies virus?

What antigen elicits complement fixing antibodies but is not protective?

Which preparation of anti rabies serum has now replaced equine antirabies serum in many countries?

What is the recommended dose for human rabies immune globulin (HRIG) for passive immunization?

At what age are injections for concentrated cell culture vaccines given to animals?

What is the major source of rabies virus in the bite of a rabid animal?

What is the classic mode of transmission of rabies from animals to humans?

Which form of rabies involves the vampire bat as an important host and vector?

What is the reservoir of rabies according to the text?

Which method is used to detect rabies virus antigen in live animals in corneal impressions or frozen sections of skin biopsies?

What prophylaxis is indicated for persons at high risk of contact with rabies virus, such as laboratory workers handling rabies virus or with rabid animals?

Which type of antirabic vaccine is associated with serious risk of neurological complications and has been replaced by the non-neural vaccines?

What is the ideal site for vaccination for antirabies treatment?

What is the recommended dosage schedule for a full antirabies vaccination course?

Which classification of exposure warrants the highest dose of antirabies vaccine?

What is the indication for giving a full five-injection course of antirabies vaccine after five years?

Which adverse reaction is NOT associated with antirabies vaccination?

Which herpesvirus is associated with Kaposi's sarcoma?

What is the size range of a herpesvirus virion?

Which part of the cell do varicella zoster and herpes simplex viruses establish latent infections in?

What is the major structural protein of a herpesvirus virion?

Which phase of infection involves the herpesviruses being bud from the nuclear membrane?

What is the approximate size of the capsid of a herpesvirus virion?

Which type of infection is characterized by reactivation in herpesviruses?

What do the 8nm spikes on the envelope of a herpesvirion consist of?

In which part of the cell do herpesviruses persist indefinitely?

Which type of herpes virus causes oropharyngeal disease and keratoconjunctivitis?

In which host condition can people with HSV infections be contagious even when they do not have skin lesions?

What is the drug of choice for antiviral chemotherapy for HSV infections?

Which age group is highly susceptible to HSV infection?

What is the primary manifestation of Varicella-Zoster Virus infection in normal individuals?

In what form does Varicella-Zoster Virus appear in immunocompromised individuals?

What is the typical age range for reactivation leading to the appearance of shingles?

What is the mode of transmission of Varicella-Zoster Virus?

What is the treatment for herpes infections?

What is the primary infection caused by Varicella-Zoster Virus in children?

Which virus is associated with the development of Kaposi sarcoma, a vascular tumor common in patients with AIDS?

What is the primary activity of the approximately 200 glycoprotein (G) spikes of the rabies virus?

Which virus causes chickenpox on primary infection and shingles upon reactivation?

What is the characteristic effect induced by human herpesviruses that can include intranuclear inclusion bodies?

Which virus is linked with Burkitt lymphoma of African children, nasopharyngeal carcinoma, and other lymphoproliferative disorders?

What can trigger the reactivation of herpes simplex viruses?

Which virus replicates in epithelial cells of the respiratory tract, salivary glands, and kidneys, and causes an infectious mononucleosis?

What is the common clinical manifestation of type 1 herpes simplex virus (HSV-1)?

Where does the latency of herpes simplex viruses occur mainly in normal humans?

Which virus infects T lymphocytes and causes exanthem subitum (roseola infantum) in early infancy?

Which characteristic is true for herpesviruses?

What is the morphology of all Herpesviruses?

Which virus is associated with causing Kaposi sarcoma?

What is the primary target cell for Human herpesvirus 1?

How do herpesviruses differ from other nuclear DNA viruses?

What is the mode of spread for Human herpesvirus 4 (Epstein-Barr virus)?

How do herpesviruses obtain their envelope?

What is the site of latency for herpesviruses?

Which characteristic is true for the Herpesviruses genome?

More Quizzes Like This