Indirect Hemagglutination Test
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Questions and Answers

What is the indirect hemagglutination test result in patients with invasive disease?

  • Usually positive (correct)
  • Usually negative
  • Always negative
  • Sometimes positive, sometimes negative

    • What is the indirect hemagglutination test result in asymptomatic individuals passing cysts?

  • Usually positive
  • Usually negative (correct)
  • Always positive
  • Sometimes positive, sometimes negative

    • What is the relationship between the indirect hemagglutination test and invasive disease?

  • The test is usually positive in invasive disease (correct)
  • The test is frequently negative in invasive disease
  • The test is never positive in invasive disease
  • The test is always negative in invasive disease

    • What is the relationship between the indirect hemagglutination test and asymptomatic individuals passing cysts?

    <p>The test is usually negative in asymptomatic individuals</p> Signup and view all the answers

    What can be inferred about the indirect hemagglutination test?

    <p>It is usually accurate in patients with invasive disease</p> Signup and view all the answers

    What is the effect of trophozoites invading the colonic epithelium?

    <p>Causing localized necrosis</p> Signup and view all the answers

    What kind of response occurs at the site of trophozoite invasion?

    <p>Little inflammation</p> Signup and view all the answers

    What do trophozoites secrete that causes localized necrosis?

    <p>Proteolytic enzymes</p> Signup and view all the answers

    Where do trophozoites invade?

    <p>The colonic epithelium</p> Signup and view all the answers

    What is the site of action of the enzymes secreted by trophozoites?

    <p>The colonic epithelium</p> Signup and view all the answers

    Where do the trophozoites invade after progressing into the submucosa?

    <p>Into the portal circulation</p> Signup and view all the answers

    What is the most frequent site of systemic disease in Entamoeba histolytica infection?

    <p>Liver</p> Signup and view all the answers

    What forms in the liver as a result of Entamoeba histolytica infection?

    <p>Abscesses</p> Signup and view all the answers

    What are the contents of the abscesses formed in the liver?

    <p>Trophozoites</p> Signup and view all the answers

    What stage of the parasite's life cycle is responsible for the invasion of the portal circulation?

    <p>Trophozoite</p> Signup and view all the answers

    What is the result of an indirect hemagglutination test in patients with gastrointestinal disease?

    <p>Usually positive</p> Signup and view all the answers

    What is the result of an indirect hemagglutination test in asymptomatic individuals?

    <p>Usually negative</p> Signup and view all the answers

    What is the treatment of choice for symptomatic intestinal amebiasis?

    <p>Metronidazole or Tinidazole</p> Signup and view all the answers

    What is the treatment of choice for hepatic abscesses?

    <p>Metronidazole or Tinidazole</p> Signup and view all the answers

    What is the brand name of Metronidazole?

    <p>Flagyl</p> Signup and view all the answers

    What is the main characteristic of chronic amebiasis?

    <p>Low-grade symptoms</p> Signup and view all the answers

    What is a possible symptom of chronic amebiasis?

    <p>Occasional diarrhea</p> Signup and view all the answers

    What is another possible symptom of chronic amebiasis?

    <p>Weight loss</p> Signup and view all the answers

    What is a low-grade symptom of chronic amebiasis?

    <p>Fatigue</p> Signup and view all the answers

    What is the general nature of the symptoms of chronic amebiasis?

    <p>Low-grade</p> Signup and view all the answers

    Study Notes

    Indirect Hemagglutination Test

    • Usually positive in patients with invasive disease
    • Frequently negative in asymptomatic individuals who are passing cysts

    Treatment of Amebiasis

    • Symptomatic intestinal amebiasis and hepatic abscesses: treated with metronidazole (Flagyl) or tinidazole

    Pathogenesis of Amebiasis

    • Trophozoites invade the colonic epithelium and secrete enzymes that cause localized necrosis
    • Little inflammation occurs at the site of invasion
    • Progression into the submucosa leads to invasion of the portal circulation by the trophozoites
    • The liver is the most frequent site of systemic disease, where abscesses containing trophozoites form

    Clinical Manifestations of Amebiasis

    • Chronic amebiasis: low-grade symptoms, including occasional diarrhea, weight loss, and fatigue

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    Description

    This quiz assesses knowledge about the indirect hemagglutination test, its results in patients with invasive disease and asymptomatic individuals. Understand the test's applications and limitations.

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