Podcast
Questions and Answers
What is the role of Glucagon-like peptide 1 (GLP-1) in insulin secretion?
What is the role of Glucagon-like peptide 1 (GLP-1) in insulin secretion?
- Increases glucagon secretion
- Inhibits insulin secretion
- Has no effect on insulin secretion
- Stimulates insulin secretion (correct)
Which cells secrete Glucagon-like peptide 1 (GLP-1)?
Which cells secrete Glucagon-like peptide 1 (GLP-1)?
- Beta cells
- Intestinal L cells (correct)
- Intestinal K cells
- Alpha cells
How do incretins like GIP and GLP-1 act on Beta cells?
How do incretins like GIP and GLP-1 act on Beta cells?
- By inhibiting insulin receptors
- By blocking cAMP production
- By binding to specific cell surface receptors (correct)
- By promoting glucagon release
What effect does cytosolic glutamate derived from Malate Aspartate shuttle have on insulin secretion?
What effect does cytosolic glutamate derived from Malate Aspartate shuttle have on insulin secretion?
In an incretin unresponsive insulin-secreting Beta cell line, what is found to be diminished?
In an incretin unresponsive insulin-secreting Beta cell line, what is found to be diminished?
What is the primary mechanism by which dietary amino acids induce insulin secretion?
What is the primary mechanism by which dietary amino acids induce insulin secretion?
What is the role of the Malate Aspartate shuttle in incretin-induced insulin secretion?
What is the role of the Malate Aspartate shuttle in incretin-induced insulin secretion?
How do the incretin hormones GIP and GLP-1 stimulate insulin secretion from pancreatic beta cells?
How do the incretin hormones GIP and GLP-1 stimulate insulin secretion from pancreatic beta cells?
What is the effect of diminished cytosolic glutamate production in an incretin unresponsive insulin-secreting beta cell line?
What is the effect of diminished cytosolic glutamate production in an incretin unresponsive insulin-secreting beta cell line?
What is the role of cAMP-Protein Kinase A signaling in incretin-induced insulin secretion?
What is the role of cAMP-Protein Kinase A signaling in incretin-induced insulin secretion?
