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Questions and Answers
Define passive immunotherapy against bacterial infections.
Passive immunotherapy against bacterial infections involves the transfer of pre-formed antibodies to provide immediate protection.
What is ADCC and how does it relate to immunotherapy against bacterial infections?
ADCC stands for Antibody-Dependent Cell-Mediated Cytotoxicity. It is a mechanism where certain immune cells recognize and destroy target cells that have been bound by specific antibodies. ADCC is relevant in immunotherapy against bacterial infections as it enhances the immune response to eliminate bacterial pathogens.
What are the advantages and disadvantages of polyclonal and monoclonal antibodies in immunotherapy?
Polyclonal antibodies offer a diverse range of targets and can provide a robust immune response, but they may have batch-to-batch variability. Monoclonal antibodies have high specificity and consistency, but may have limited range of targets.
What are IgY and single-domain ('nanobodies') antibodies, and how are they relevant to immunotherapy against bacterial infections?
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What is the significance of passive immunization preclinical and clinical trials in the context of tackling bacterial infections?
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