Immunology [PHAR 308] Chapter 1 Learning Outcomes Quiz
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Questions and Answers

Who is often attributed with the discovery that cowpox induces protection against human smallpox?

  • Maryam AlRamadan
  • Louis Pasteur
  • Louis Pasteur and Edward Jenner
  • Edward Jenner (correct)
  • What is the main function of the immune system?

  • To cause diseases in the body
  • To recognize and protect the body from infections (correct)
  • To induce protection against smallpox
  • To produce infectious and pathogenic microbes
  • What is the origin of immunology usually attributed to?

  • Edward Jenner (correct)
  • Maryam AlRamadan
  • Father of immunology
  • Louis Pasteur
  • From which type of cells are all cellular blood components derived through the process of hematopoiesis?

    <p>Hematopoietic stem cells (HSCs)</p> Signup and view all the answers

    Where are hematopoietic stem cells (HSCs) found in adults?

    <p>Bone marrow</p> Signup and view all the answers

    Which cells are included in the myeloid cells?

    <p>Neutrophils and Eosinophils</p> Signup and view all the answers

    Which cells are part of the innate immune system?

    <p>Neutrophils</p> Signup and view all the answers

    Where do macrophages originate from?

    <p>Circulation</p> Signup and view all the answers

    What is the main function of alveolar macrophages?

    <p>Initiation and control of immunity to respiratory pathogens</p> Signup and view all the answers

    What type of macrophages are found in the liver?

    <p>Kupffer cells</p> Signup and view all the answers

    Which plasma proteins can macrophages detect using recognition receptors?

    <p>MBL and CRP</p> Signup and view all the answers

    What do macrophages produce to kill phagocytosed bacteria?

    <p>Reactive oxygen species, such as nitric oxide</p> Signup and view all the answers

    Study Notes

    Immunology Fundamentals

    • Edward Jenner is often attributed with the discovery that cowpox induces protection against human smallpox.

    Immune System Function

    • The main function of the immune system is to protect the body against infectious organisms and other foreign substances.

    Origin of Immunology

    • The origin of immunology is usually attributed to Edward Jenner.

    Blood Cell Development

    • All cellular blood components are derived from hematopoietic stem cells (HSCs) through the process of hematopoiesis.

    Hematopoietic Stem Cell Location

    • In adults, hematopoietic stem cells (HSCs) are found in the bone marrow.

    Myeloid Cells

    • Myeloid cells include monocytes, macrophages, neutrophils, basophils, and eosinophils.

    Innate Immune System

    • The innate immune system includes cells such as neutrophils, macrophages, dendritic cells, and eosinophils.

    Macrophage Origin

    • Macrophages originate from monocytes.

    Alveolar Macrophage Function

    • The main function of alveolar macrophages is to remove debris and other foreign substances from the lungs.

    Liver Macrophages

    • Macrophages found in the liver are called Kupffer cells.

    Macrophage Recognition Receptors

    • Macrophages can detect pathogens using recognition receptors that recognize pathogen-associated molecular patterns (PAMPs) and other plasma proteins.

    Bactericidal Action

    • Macrophages produce reactive oxygen species (ROS) to kill phagocytosed bacteria.

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    Description

    Test your understanding of Immunology [PHAR 308] Chapter 1 with this quiz covering topics such as WBCs development, differences between innate and adaptive immunity, differences between granulocytes and agranulocytes, line of defenses, and macrophages.

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