Podcast
Questions and Answers
What is the role of IL-2 in lymphocyte activation?
What is the role of IL-2 in lymphocyte activation?
- Induces the differentiation of Th1 cells
- Stimulates the expansion of Th2 cells
- Promotes the differentiation of Treg cells
- Enhances the proliferation of cytotoxic T-cells (correct)
What is the primary site of Th2 effector function?
What is the primary site of Th2 effector function?
- Lymph nodes
- Liver
- Skin
- Mucosal surfaces (correct)
How do Treg cells differ from other types of Th cells?
How do Treg cells differ from other types of Th cells?
- They primarily function in pathogen clearance
- They secrete pro-inflammatory cytokines
- They promote inflammation and immune response
- They suppress immune responses (correct)
Which cytokines are associated with polarizing Th1 cells?
Which cytokines are associated with polarizing Th1 cells?
What is the concept of cross-regulation between Th cells?
What is the concept of cross-regulation between Th cells?
How does signal 1b aid in the regulation of Th cells?
How does signal 1b aid in the regulation of Th cells?
What is the main function of CD4+ helper T-lymphocytes?
What is the main function of CD4+ helper T-lymphocytes?
What is the major costimulator involved in T cell activation?
What is the major costimulator involved in T cell activation?
What happens when T cell recognition of antigen occurs in the absence of co-stimulation?
What happens when T cell recognition of antigen occurs in the absence of co-stimulation?
What is the main role of interleukin 2 (IL-2) in T cell activation?
What is the main role of interleukin 2 (IL-2) in T cell activation?
What is the purpose of T-cell polarization?
What is the purpose of T-cell polarization?
What are DAMPs and PAMPs involved in?
What are DAMPs and PAMPs involved in?
What happens when anergic T cells encounter antigens presented by APCs that express co-stimulatory molecules?
What happens when anergic T cells encounter antigens presented by APCs that express co-stimulatory molecules?
What is the main role of CD28 on the T helper cell (Th)?
What is the main role of CD28 on the T helper cell (Th)?
What does IL-2 binding to the Th IL-2R act as?
What does IL-2 binding to the Th IL-2R act as?
