Podcast
Questions and Answers
What is the primary function of the constant region of the light chain?
What is the primary function of the constant region of the light chain?
- To interact with different immune responses and effector cells
- To provide variability in antibody production
- To bring together the light and heavy chains (correct)
- To specify the antibody's antigen-binding site
How many constant domains are present in a heavy chain?
How many constant domains are present in a heavy chain?
- 3 or 4 (correct)
- 7 or 8
- 5 or 6
- 1 or 2
What is the purpose of somatic recombination in the generation of antigen receptors?
What is the purpose of somatic recombination in the generation of antigen receptors?
- To combine the light and heavy chains
- To increase the diversity of the antibody repertoire
- To reduce the variability of the antibody response
- To permenantly change the DNA of the heavy chain locus (correct)
What is the role of the hypervariable regions in the antigen-antibody interaction?
What is the role of the hypervariable regions in the antigen-antibody interaction?
What is the result of combining the V, D, and J segments in the heavy chain locus?
What is the result of combining the V, D, and J segments in the heavy chain locus?
What is the purpose of RAG proteins in V(D)J recombination?
What is the purpose of RAG proteins in V(D)J recombination?
What is the result of the cleavage reaction in V(D)J recombination?
What is the result of the cleavage reaction in V(D)J recombination?
What is the role of Ku proteins in V(D)J recombination?
What is the role of Ku proteins in V(D)J recombination?
What is the result of somatic hypermutation in B cells?
What is the result of somatic hypermutation in B cells?
What is the purpose of the tetrameric complex of RAG1 and RAG2 in V(D)J recombination?
What is the purpose of the tetrameric complex of RAG1 and RAG2 in V(D)J recombination?
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