10 Questions
What is the primary function of the constant region of the light chain?
To bring together the light and heavy chains
How many constant domains are present in a heavy chain?
3 or 4
What is the purpose of somatic recombination in the generation of antigen receptors?
To permenantly change the DNA of the heavy chain locus
What is the role of the hypervariable regions in the antigen-antibody interaction?
To generate a high level of antigen specificity
What is the result of combining the V, D, and J segments in the heavy chain locus?
A diverse range of variable exons
What is the purpose of RAG proteins in V(D)J recombination?
To recognize and cleave the RSS regions
What is the result of the cleavage reaction in V(D)J recombination?
A blunt double-strand break at the coding ends
What is the role of Ku proteins in V(D)J recombination?
To recruit DNA ligase to join the signal ends
What is the result of somatic hypermutation in B cells?
An increase in the diversity of antibodies
What is the purpose of the tetrameric complex of RAG1 and RAG2 in V(D)J recombination?
To bind to the RSS regions
Test your knowledge of antigen receptors, antibodies, and their structure, including heavy and light chains, variable and constant regions, and more.
Make Your Own Quizzes and Flashcards
Convert your notes into interactive study material.
Get started for free
