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Questions and Answers
What is the primary function of the constant region of the light chain?
What is the primary function of the constant region of the light chain?
- To interact with different immune responses and effector cells
- To provide variability in antibody production
- To bring together the light and heavy chains (correct)
- To specify the antibody's antigen-binding site
How many constant domains are present in a heavy chain?
How many constant domains are present in a heavy chain?
- 3 or 4 (correct)
- 7 or 8
- 5 or 6
- 1 or 2
What is the purpose of somatic recombination in the generation of antigen receptors?
What is the purpose of somatic recombination in the generation of antigen receptors?
- To combine the light and heavy chains
- To increase the diversity of the antibody repertoire
- To reduce the variability of the antibody response
- To permenantly change the DNA of the heavy chain locus (correct)
What is the role of the hypervariable regions in the antigen-antibody interaction?
What is the role of the hypervariable regions in the antigen-antibody interaction?
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What is the result of combining the V, D, and J segments in the heavy chain locus?
What is the result of combining the V, D, and J segments in the heavy chain locus?
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What is the purpose of RAG proteins in V(D)J recombination?
What is the purpose of RAG proteins in V(D)J recombination?
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What is the result of the cleavage reaction in V(D)J recombination?
What is the result of the cleavage reaction in V(D)J recombination?
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What is the role of Ku proteins in V(D)J recombination?
What is the role of Ku proteins in V(D)J recombination?
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What is the result of somatic hypermutation in B cells?
What is the result of somatic hypermutation in B cells?
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What is the purpose of the tetrameric complex of RAG1 and RAG2 in V(D)J recombination?
What is the purpose of the tetrameric complex of RAG1 and RAG2 in V(D)J recombination?
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