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16 Questions

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Immunology: Defense Against Infection

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Questions and Answers

What are the two classes of MHC proteins found in the body?

Class IV MHC proteins and Class V MHC proteins

Class I MHC proteins and Class III MHC proteins

Class III MHC proteins and Class IV MHC proteins

Class I MHC proteins and Class II MHC proteins (correct)

What type of graft is transplanted from one part of the body to another?

Xenograft

Isograft

Autograft (correct)

Allograft

What is the primary function of Toll-like receptors in the immune response?

To produce antibodies against antigens

To recognize and respond to pathogen-associated molecular patterns (correct)

To recognize and bind to specific antigens

To facilitate phagocytosis of foreign particles

What is the purpose of ABO blood typing?

To classify blood based on the presence of inherited antigenic carbohydrates on the surface of red blood cells Signup and view all the answers

What is the purpose of a cytotoxic cross match test in transplantation?

To detect the presence of anti-donor antibodies in the recipient's serum Signup and view all the answers

What is the primary function of phagocytosis in the immune response?

To engulf and eliminate foreign particles and cellular debris Signup and view all the answers

What type of antibody is typically attached to the surface of B cells?

IgD Signup and view all the answers

What is the primary function of lymph nodes in the immune system?

To act as filters, collecting and destroying bacteria and viruses Signup and view all the answers

What is the role of CD8+ T cells in the adaptive immune system?

To destroy infected cells by recognizing antigens presented on MHC-I Signup and view all the answers

What is the term for the small, accessible portion of an antigen that is recognized by lymphocytes?

Epitope Signup and view all the answers

What type of antibody is responsible for preventing attachment of pathogens to epithelial cell surfaces?

IgA Signup and view all the answers

What is the term for the binding of the Fc portion of an antibody to the Fc-receptor on an effector cell?

Immunoglobin binding Signup and view all the answers

What is the estimated number of different antibody molecules in an individual?

1000 Signup and view all the answers

What is the primary reason for using humanized antibodies over mouse antibodies?

To reduce the risk of inducing human anti-mouse antibodies Signup and view all the answers

What is the primary site of mucosal immunity in the body?

Intestinal mucous epithelium Signup and view all the answers

What is the primary function of macrophages in the immune system?

To collect and destroy bacteria and viruses Signup and view all the answers