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Immunology: Defense Against Infection

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16 Questions

What are the two classes of MHC proteins found in the body?

Class I MHC proteins and Class II MHC proteins

What type of graft is transplanted from one part of the body to another?

Autograft

What is the primary function of Toll-like receptors in the immune response?

To recognize and respond to pathogen-associated molecular patterns

What is the purpose of ABO blood typing?

To classify blood based on the presence of inherited antigenic carbohydrates on the surface of red blood cells

What is the purpose of a cytotoxic cross match test in transplantation?

To detect the presence of anti-donor antibodies in the recipient's serum

What is the primary function of phagocytosis in the immune response?

To engulf and eliminate foreign particles and cellular debris

What type of antibody is typically attached to the surface of B cells?

IgD

What is the primary function of lymph nodes in the immune system?

To act as filters, collecting and destroying bacteria and viruses

What is the role of CD8+ T cells in the adaptive immune system?

To destroy infected cells by recognizing antigens presented on MHC-I

What is the term for the small, accessible portion of an antigen that is recognized by lymphocytes?

Epitope

What type of antibody is responsible for preventing attachment of pathogens to epithelial cell surfaces?

IgA

What is the term for the binding of the Fc portion of an antibody to the Fc-receptor on an effector cell?

Immunoglobin binding

What is the estimated number of different antibody molecules in an individual?

1000

What is the primary reason for using humanized antibodies over mouse antibodies?

To reduce the risk of inducing human anti-mouse antibodies

What is the primary site of mucosal immunity in the body?

Intestinal mucous epithelium

What is the primary function of macrophages in the immune system?

To collect and destroy bacteria and viruses

Test your knowledge of the immune system, including barriers against infection, non-specific diseases, and specific immune responses. Learn about phagocytosis, toll-like receptors, and antigen recognition.

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