Podcast
Questions and Answers
What characterizes many of the genes mutated in primary immunodeficiencies?
What characterizes many of the genes mutated in primary immunodeficiencies?
- They are multifunctional and involved in several important pathways. (correct)
- They are only involved in one important pathway.
- They are exclusively involved in autoimmunity.
- They are redundant and thereby not crucial for immune function.
What is the main challenge in selecting genes to study in primary immunodeficiencies?
What is the main challenge in selecting genes to study in primary immunodeficiencies?
- Identifying the genes that are multifunctional.
- Distinguishing the genes that are redundant.
- Selecting the genes that are important to students of Clinical Immunology. (correct)
- Choosing the genes that are involved in autoimmunity.
Who is credited with helping to keep the author's rheumatology up to date?
Who is credited with helping to keep the author's rheumatology up to date?
- Georg Hollander.
- Meilyn Hew.
- Siraj Misbah. (correct)
- Beth Psaila.
What is the characteristic of CD18/CD11 deficiency?
What is the characteristic of CD18/CD11 deficiency?
What is the result of defective expression of CD15?
What is the result of defective expression of CD15?
What is mediated by E-selectin (CD62E) and Sialyl Lewis X (CD15)?
What is mediated by E-selectin (CD62E) and Sialyl Lewis X (CD15)?
What is characteristic of Glanzmann’s disease?
What is characteristic of Glanzmann’s disease?
What is mediated by ICAM-1 on endothelium?
What is mediated by ICAM-1 on endothelium?
What is the main consequence of gene mutations in IL-12 receptor or IFN-γ receptor deficiencies?
What is the main consequence of gene mutations in IL-12 receptor or IFN-γ receptor deficiencies?
Which of the following cytokines is NOT part of the IL-10 family?
Which of the following cytokines is NOT part of the IL-10 family?
What is the function of Fc receptors on phagocytic cells and NK cells?
What is the function of Fc receptors on phagocytic cells and NK cells?
What is the common structural chain shared by the receptors for IL-2, IL-4, IL-7, IL-9, IL-15, and IL-23?
What is the common structural chain shared by the receptors for IL-2, IL-4, IL-7, IL-9, IL-15, and IL-23?
What is the characteristic of chemokine receptors?
What is the characteristic of chemokine receptors?
What is the purpose of the redundancy in cytokine receptors?
What is the purpose of the redundancy in cytokine receptors?
