Immunology: Antigen-Antibody Reactions
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Questions and Answers

What is the primary function of an antibody in response to antigen exposure?

  • To recognize and bind to a specific epitope with low specificity
  • To destroy the antigen without binding to it
  • To recognize and bind to a particular antigen with high specificity (correct)
  • To inhibit the immune response to the antigen

    • What is the typical size of an epitope?

  • 15-20 amino acids
  • 5-7 amino acids
  • 10-12 amino acids (correct)
  • 20-25 amino acids

    • What is the result of the interaction between an antibody and an antigen?

  • The antibody changes shape, exposing a new site for antigen binding (correct)
  • The antibody and antigen bind, but the immune response is inhibited
  • The antigen changes shape, making it more susceptible to destruction
  • The antibody and antigen remain unchanged, but the immune response is triggered

    • Which of the following is NOT a type of microbe that can stimulate an immune response?

    <p>Egg white</p> Signup and view all the answers

    What is the term for the part of an antigen that interacts with an antibody?

    <p>Epitope</p> Signup and view all the answers

    What is produced in response to exposure to an antigen?

    <p>Antibody</p> Signup and view all the answers

    What is the primary function of the Fc portion of an antibody?

    <p>To direct the biological activity of the antibody</p> Signup and view all the answers

    What type of bonds are responsible for holding the antigen to the antibody combining site?

    <p>Non-covalent bonds</p> Signup and view all the answers

    What is the consequence of the antigen-antibody reaction occurring via non-covalent bonds?

    <p>The reaction is reversible</p> Signup and view all the answers

    What is the term for the regions of the antibody that provide specificity for binding an epitope of an antigen?

    <p>Complementarity-determining regions</p> Signup and view all the answers

    What is the name of the concept that describes the interaction between antibodies and antigens?

    <p>Lock and Key Concept</p> Signup and view all the answers

    What is the term for the visualization of antigen-antibody reactions?

    <p>All of the above</p> Signup and view all the answers

    Which of the following techniques utilizes a laser beam to count and separate cells stained with fluorescent antibody?

    <p>Flow Cytometry</p> Signup and view all the answers

    What is the purpose of incubating a sample with a known, labeled antigen or antibody in Radioimmunoassay (RIA)?

    <p>To compare the amount of radioactivity present before and after incubation</p> Signup and view all the answers

    In the Western Blot technique, what is the purpose of transferring the gel to a special blotter?

    <p>To bind the reactants in place</p> Signup and view all the answers

    What is the significance of the laser beam in Flow Cytometry?

    <p>It excites fluorescently tagged antibodies</p> Signup and view all the answers

    What is the main advantage of using Enzyme-Linked Immunosorbent Assay (ELISA)?

    <p>It is a highly specific and sensitive assay</p> Signup and view all the answers

    What is the primary application of Flow Cytometry in medical diagnosis?

    <p>Cancer diagnosis and monitoring</p> Signup and view all the answers

    What is the primary purpose of agglutination testing?

    <p>To determine ABO and Rh blood types</p> Signup and view all the answers

    In a latex agglutination test, what is affixed to the tiny latex beads?

    <p>Antigens</p> Signup and view all the answers

    What is the term for the interaction of a soluble antigen with a soluble antibody to form an insoluble complex?

    <p>Precipitation</p> Signup and view all the answers

    What is the purpose of the VDRL test?

    <p>To diagnose streptococcal infections</p> Signup and view all the answers

    What is required for the action of lysin or cytolysin?

    <p>Both antibody and complement</p> Signup and view all the answers

    What is the difference between direct and indirect fluorescent antibody testing?

    <p>Direct testing uses a fluorescent antibody solution, while indirect testing uses a non-fluorescent antibody solution</p> Signup and view all the answers

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