12 Questions
Which cytokines have been shown to maintain memory cells?
IL-7 and IL-15
How do most memory cells exist?
In a resting state
What allows pathogens to escape immune defenses?
Antigenic variation
How do some viruses persist within the host?
By ceasing to replicate until immunity wanes
How does Mycobacterium tuberculosis (TB) survive within the host?
By preventing fusion of phagosome and lysosome
What kind of infections suggest a defect in host defense mediated by T lymphocytes?
Recurrent viral infections
What can result from defects in complement components?
Defective humoral immune function
What does human immunodeficiency syndrome (HIV) infect?
CD4 T cells, dendritic cells, and macrophages
What confers resistance to HIV infection?
Genetic deficiency of the macrophage chemokine coreceptor (CCR5)
What does the integration of HIV DNA into the host genome depend on?
Host-cell transcription factors induced upon activation of infected T cells
What leads to a rapid increase in CD4 cells and decrease in virus titre in HIV treatment?
Drugs that block HIV replication
What is allergy mediated by?
IgE
Test your knowledge of immunological memory and the role of cytokines in directing T helper cell responses with this quiz. Explore the mechanisms of immune system failure and the cross-regulation between Th1 and Th2 cells. Evaluate your understanding of clonally expanded populations and the rapid, effective immune response to previously encountered pathogens.
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