18 Questions
Which type of immunoglobulin is the first to be produced in response to an antigen?
IgM
What is the main function of the Fc fragment of an antibody?
Complement activation
What is the primary role of secretory IgA (SIgA) in the body?
Providing mucosal immunity
Which class of immunoglobulin is primarily found on the surface of B cells?
IgD
How do the light chains of an antibody differ from the heavy chains?
Light chains have a variable region, heavy chains do not
Which type of immunoglobulin is primarily responsible for activating the classical complement pathway?
IgM
Which immunoglobulin is the most efficient in activating complement via the Classical pathway?
IgM
Which immunoglobulin is NOT opsonic?
IgM
Which immunoglobulin is inactivated by IgA protease produced by certain bacteria?
IgA
Which immunoglobulin is predominant in various secretions such as tear, saliva, and colostrum?
Secretory IgA (sIgA)
Which immunoglobulin acts as an antigen receptor on naive B lymphocytes?
IgD
Which immunoglobulin is associated with Type I hypersensitivity reactions such as atopy and anaphylaxis?
IgE
Which of the following statements about IgM is correct?
IgM is the only antibody capable of binding to carbohydrate antigens like ABO blood group antigens.
What is the structure of IgM?
A pentamer consisting of 5 monomeric units linked by a J chain and disulfide bonds at the Fc fragment.
Which of the following fragments is produced when an antibody is digested by papain?
Two Fab fragments and one Fc fragment
Which immunoglobulin class is effective as an antitoxin?
IgG
What is the role of IgA in the body?
It plays a crucial role in mucosal immunity.
Which immunoglobulin class is associated with the function of IgD?
IgD
Test your knowledge on the characteristics and functions of different types of immunoglobulins such as IgM and IgA. Explore their structures, biological activities, and interactions with pathogens.
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