Immunoglobulins Overview

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Questions and Answers

Which type of immunoglobulin is the first to be produced in response to an antigen?

  • IgA
  • IgG
  • IgE
  • IgM (correct)

What is the main function of the Fc fragment of an antibody?

  • Cytokine production
  • Phagocytosis
  • Complement activation (correct)
  • Antigen binding

What is the primary role of secretory IgA (SIgA) in the body?

  • Neutralizing toxins
  • Providing mucosal immunity (correct)
  • Opsonizing pathogens
  • Activating the complement system

Which class of immunoglobulin is primarily found on the surface of B cells?

<p>IgD (C)</p> Signup and view all the answers

How do the light chains of an antibody differ from the heavy chains?

<p>Light chains have a variable region, heavy chains do not (D)</p> Signup and view all the answers

Which type of immunoglobulin is primarily responsible for activating the classical complement pathway?

<p>IgM (A)</p> Signup and view all the answers

Which immunoglobulin is the most efficient in activating complement via the Classical pathway?

<p>IgM (C)</p> Signup and view all the answers

Which immunoglobulin is NOT opsonic?

<p>IgM (C)</p> Signup and view all the answers

Which immunoglobulin is inactivated by IgA protease produced by certain bacteria?

<p>IgA (C)</p> Signup and view all the answers

Which immunoglobulin is predominant in various secretions such as tear, saliva, and colostrum?

<p>Secretory IgA (sIgA) (C)</p> Signup and view all the answers

Which immunoglobulin acts as an antigen receptor on naive B lymphocytes?

<p>IgD (B)</p> Signup and view all the answers

Which immunoglobulin is associated with Type I hypersensitivity reactions such as atopy and anaphylaxis?

<p>IgE (B)</p> Signup and view all the answers

Which of the following statements about IgM is correct?

<p>IgM is the only antibody capable of binding to carbohydrate antigens like ABO blood group antigens. (C)</p> Signup and view all the answers

What is the structure of IgM?

<p>A pentamer consisting of 5 monomeric units linked by a J chain and disulfide bonds at the Fc fragment. (A)</p> Signup and view all the answers

Which of the following fragments is produced when an antibody is digested by papain?

<p>Two Fab fragments and one Fc fragment (A)</p> Signup and view all the answers

Which immunoglobulin class is effective as an antitoxin?

<p>IgG (B)</p> Signup and view all the answers

What is the role of IgA in the body?

<p>It plays a crucial role in mucosal immunity. (C)</p> Signup and view all the answers

Which immunoglobulin class is associated with the function of IgD?

<p>IgD (C)</p> Signup and view all the answers

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