Immunoglobulins Overview
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Questions and Answers

Which type of immunoglobulin is the first to be produced in response to an antigen?

  • IgA
  • IgG
  • IgE
  • IgM (correct)
  • What is the main function of the Fc fragment of an antibody?

  • Cytokine production
  • Phagocytosis
  • Complement activation (correct)
  • Antigen binding
  • What is the primary role of secretory IgA (SIgA) in the body?

  • Neutralizing toxins
  • Providing mucosal immunity (correct)
  • Opsonizing pathogens
  • Activating the complement system
  • Which class of immunoglobulin is primarily found on the surface of B cells?

    <p>IgD</p> Signup and view all the answers

    How do the light chains of an antibody differ from the heavy chains?

    <p>Light chains have a variable region, heavy chains do not</p> Signup and view all the answers

    Which type of immunoglobulin is primarily responsible for activating the classical complement pathway?

    <p>IgM</p> Signup and view all the answers

    Which immunoglobulin is the most efficient in activating complement via the Classical pathway?

    <p>IgM</p> Signup and view all the answers

    Which immunoglobulin is NOT opsonic?

    <p>IgM</p> Signup and view all the answers

    Which immunoglobulin is inactivated by IgA protease produced by certain bacteria?

    <p>IgA</p> Signup and view all the answers

    Which immunoglobulin is predominant in various secretions such as tear, saliva, and colostrum?

    <p>Secretory IgA (sIgA)</p> Signup and view all the answers

    Which immunoglobulin acts as an antigen receptor on naive B lymphocytes?

    <p>IgD</p> Signup and view all the answers

    Which immunoglobulin is associated with Type I hypersensitivity reactions such as atopy and anaphylaxis?

    <p>IgE</p> Signup and view all the answers

    Which of the following statements about IgM is correct?

    <p>IgM is the only antibody capable of binding to carbohydrate antigens like ABO blood group antigens.</p> Signup and view all the answers

    What is the structure of IgM?

    <p>A pentamer consisting of 5 monomeric units linked by a J chain and disulfide bonds at the Fc fragment.</p> Signup and view all the answers

    Which of the following fragments is produced when an antibody is digested by papain?

    <p>Two Fab fragments and one Fc fragment</p> Signup and view all the answers

    Which immunoglobulin class is effective as an antitoxin?

    <p>IgG</p> Signup and view all the answers

    What is the role of IgA in the body?

    <p>It plays a crucial role in mucosal immunity.</p> Signup and view all the answers

    Which immunoglobulin class is associated with the function of IgD?

    <p>IgD</p> Signup and view all the answers

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