Immunity to Microbes: Overview
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Questions and Answers

The TH17 cells recruit neutrophils and ______

monocytes

Viruses are obligatory intracellular microorganisms that live inside cells. They use components of the nucleic acid and protein synthetic machinery of the host to replicate and spread. Viruses typically infect various cell types by using normal cell surface receptors to enter the cells. This is an example of ______ immunity to viruses.

innate

Inhibition of infection by IFN-I, NK cell-mediated killing, and recognition of viral RNA and DNA by endosomal TLRs and cytoplasmic RIG-like receptors are examples of mechanisms in ______ immunity to viruses.

innate

Antibodies block virus binding and entry into host cells. This is an example of ______ immunity to viruses.

<p>adaptive</p> Signup and view all the answers

Abs are effective only during the extracellular stage. Antibodies induced by previous infection or vaccination can protect from viral infection. This is an example of ______ immunity to viruses.

<p>adaptive</p> Signup and view all the answers

CTLs eliminate the infection by killing infected cells. Virus-specific CTLs recognize viral peptides presented by class I MHC molecules. This is an example of ______ immunity to viruses.

<p>adaptive</p> Signup and view all the answers

In latent infections, viral DNA persists in host cells, but the virus does not replicate or kill infected cells. CTLs are generated in response to the virus that can control the infection but not eradicate it. This is an example of ______ effects of immunity.

<p>injurious</p> Signup and view all the answers

In some viral infections, tissue injury may be caused by CTLs. Hepatitis B virus infection recruits CTLs which destroy ______.

<p>hepatocytes</p> Signup and view all the answers

TH17 cells are known for their responses to ______.

<p>fungi</p> Signup and view all the answers

NK cells recognize infected cells that have shut off class I MHC expression as an escape mechanism from CTLs. This is a feature of ______ immunity to viruses.

<p>innate</p> Signup and view all the answers

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