Immunity Basics and Vaccine Types
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What is the recommended action for children aged 6-9 months receiving the measles vaccine?

  • They should receive only one dose.
  • They must wait until 12 months to receive a second dose.
  • They should be isolated for four days after vaccination.
  • They should receive a second dose as soon as possible after 9 months. (correct)
  • Why should malnourished children with measles be isolated?

  • To reduce the risk of secondary infections.
  • To monitor their nutritional intake during illness.
  • To prevent transmission of the virus to healthy children. (correct)
  • To avoid complications related to malnutrition.
  • How can vitamin A be administered according to the content?

  • Only after measles symptoms appear.
  • Anytime regardless of vaccination schedule.
  • At the same time as the measles vaccine in deficient areas. (correct)
  • Only during hospitalization for measles.
  • What is the primary method of hepatitis B transmission mentioned?

    <p>By sharing unsterilized needles or syringes.</p> Signup and view all the answers

    When is the designated immunization day in government health facilities?

    <p>On Wednesdays unless revised by local customs.</p> Signup and view all the answers

    What type of immunity is developed by the body's own immune system?

    <p>Active immunity</p> Signup and view all the answers

    What happens to passive immunity over time?

    <p>It wanes after a few weeks or months</p> Signup and view all the answers

    How do live-attenuated vaccines function in the body?

    <p>They cause no or very mild disease due to weakened pathogens</p> Signup and view all the answers

    What characterizes inactivated vaccines?

    <p>They use killed microorganisms that cannot cause disease</p> Signup and view all the answers

    Which of the following vaccines uses a specific, isolated protein of a pathogen?

    <p>Subunit vaccines</p> Signup and view all the answers

    What is the primary purpose of a vaccine?

    <p>To help the immune system recognize and fight pathogens</p> Signup and view all the answers

    What is a common feature of live-attenuated vaccines?

    <p>They can grow in a vaccinated individual with mild effects</p> Signup and view all the answers

    Which types of vaccines are effective against life-threatening diseases?

    <p>Vaccines of all types can protect against various diseases</p> Signup and view all the answers

    What is the effectiveness of the measles vaccine?

    <p>85%</p> Signup and view all the answers

    What age group is at greatest risk of developing severe Rotavirus infection?

    <p>Children aged 6 to 24 months</p> Signup and view all the answers

    Which vaccine is particularly responsible for causing severe illnesses like meningitis and pneumonia in children?

    <p>Hib vaccine</p> Signup and view all the answers

    Which of the following is NOT recommended when administering vaccines to infants?

    <p>Mixing different vaccines in one syringe before injection</p> Signup and view all the answers

    Which vaccine is specifically indicated for administration as a birth dose?

    <p>Monovalent hepatitis B vaccine</p> Signup and view all the answers

    What is the correct sequence for coadministration of vaccines?

    <p>OPV first, followed by Rotavirus vaccine</p> Signup and view all the answers

    What must not happen when administering the OPV vaccine?

    <p>Letting the dropper touch the child's tongue</p> Signup and view all the answers

    Which statement is correct regarding vaccination series for infants?

    <p>All EPI antigens can be administered at the same time</p> Signup and view all the answers

    What is the target percentage for immunization of infants/children against common vaccine-preventable diseases in the Philippines?

    <p>100%</p> Signup and view all the answers

    Who is responsible for calculating the vaccine requirements at the RHU/health center level?

    <p>Public Health Nurse</p> Signup and view all the answers

    Which formula is used to estimate the number of pregnant women in the eligible population?

    <p>total population x 3.5%</p> Signup and view all the answers

    What is the correct temperature range for storing OPV vaccines?

    <p>-15 to -25⁰C</p> Signup and view all the answers

    Which of the following vaccines is stored in the refrigerator at temperatures of +2 to +8⁰C?

    <p>Measles</p> Signup and view all the answers

    What is the primary responsibility of the Cold Chain Officer?

    <p>Maintain cold chain equipment and supplies</p> Signup and view all the answers

    In the event of an electrical breakdown, what should the Cold Chain Officer implement?

    <p>An emergency plan for the cold chain</p> Signup and view all the answers

    Which of the following requirements is significant for maintaining the potency of EPI vaccines?

    <p>Maintain the cold chain</p> Signup and view all the answers

    Which vaccines should not be stored in the freezer due to potential damage?

    <p>Hepatitis B vaccine</p> Signup and view all the answers

    What is the maximum duration for which multidose vaccines can be used after opening?

    <p>4 weeks</p> Signup and view all the answers

    Which one of the following is NOT a requirement to use multidose vials post-opening?

    <p>The vaccine has been contaminated</p> Signup and view all the answers

    What should the VVM on a vaccine vial help to indicate?

    <p>The cumulative heat exposure of the vaccine</p> Signup and view all the answers

    What special precaution must be taken with BCG vaccine?

    <p>Protect it from sunlight</p> Signup and view all the answers

    What should you do with reconstituted freeze-dried vaccines after 6 hours?

    <p>Discard them</p> Signup and view all the answers

    Under what condition can a multidose vial be opened for one or two clients?

    <p>If the health worker believes the client won't return</p> Signup and view all the answers

    What storage guideline should be followed to maintain vaccine potency?

    <p>Abide by the first expiry-first out (FEFO) policy</p> Signup and view all the answers

    Study Notes

    Immunity: Active & Passive

    • Active immunity is acquired through exposure to an antigen.
    • The immune system develops its own antibodies to fight off the antigen.
    • This type of immunity tends to be long-lasting, often persisting for a lifetime.
    • Passive immunity is acquired through the transfer of antibodies from another individual, typically via injection.
    • This type of immunity is temporary, lasting for a few weeks or months.

    Vaccine Types

    • Live-attenuated vaccines (LAV) are produced from weakened disease-causing pathogens, such as viruses or bacteria.
    • These vaccines stimulate the immune system without causing significant illness.
    • LAVs have been available since the 1950s.
    • Inactivated vaccines use killed pathogens that have been rendered harmless through physical or chemical processes.
    • Because they are inactive, they cannot cause disease.
    • Subunit vaccines only present specific antigens to the immune system, rather than the whole pathogen.
    • A common type is protein-based subunit vaccines, which use a specific, isolated protein from a pathogen.

    Measles

    • Children aged 6-9 months should receive a second dose of measles vaccine if their initial dose occurred before 9 months.
    • Children hospitalized with measles should be isolated for at least four days after the rash appears.
    • Malnourished children with measles should be isolated for the duration of their illness.

    Vitamin A

    • Approximately 124 million children under 5 years of age globally suffer from vitamin A deficiency.
    • In regions with known vitamin A deficiency, the vitamin can be administered alongside the measles vaccine or other recommended EPI vaccines.

    Pertussis

    • Not included in the supplied text.

    Tetanus

    • Not included in the supplied text.

    Hepatitis B

    • Hepatitis B is a potentially serious liver infection caused by the hepatitis B virus.
    • Transmission can occur through:
      • Exposure to infected blood, such as through unsterilized needles or syringes.
      • Mother-to-child transmission during birth.
      • Contact with infected blood or bodily fluids during social interactions.
      • Sexual intercourse.

    Yellow Fever

    • Not included in the supplied text.

    Infant & Young Children Immunization Schedule

    • Wednesday is typically designated as immunization day in government health facilities.
    • The Philippine Department of Health (DOH) prescribes the schedule and method of infant immunization.
    • The hepatitis B vaccine is administered at birth to reduce the risk of a child becoming a carrier.
    • Measles vaccine is 85% effective.
    • Rotavirus vaccine and Hib vaccine were introduced as part of EPI in 2012.
    • Rotavirus is a common cause of severe diarrhea in infants and children.
    • Hib is a bacterium responsible for serious illnesses such as meningitis and pneumonia, particularly affecting children under 5 years of age, especially those between 4 and 18 months.

    Immunization Administration: Key Considerations

    • Use a sterile syringe and needle for each client.
    • Vaccination series do not need to be restarted, regardless of the time lapsed between doses.
    • EPI antigens are safe and effective when administered simultaneously, but at different sites.
    • Mixing different vaccines in one syringe or using a fluid vaccine to reconstitute a freeze-dried vaccine is not recommended.
    • OPV is administered orally, by dropping it onto the child's tongue.
    • Only monovalent hepatitis B vaccine should be used for the birth dose, as pentavalent vaccine is not suitable for newborns.
    • The recommended sequence for coadministration of vaccines is OPV, followed by Rotavirus vaccine, and then other appropriate vaccines.

    Target Setting & Vaccine Requirements

    • The EPI goal in the Philippines is to achieve 100% immunization of infants and children against vaccine-preventable diseases.
    • The public health nurse at each RHU/health center level is responsible for monitoring vaccine allocation and requirement calculations.

    Maintaining Potency of EPI Vaccines

    • Cold Chain Management:
      • The cold chain ensures the potency of vaccines from manufacturing until administration.
      • The Cold Chain Officer is responsible for maintaining equipment and supplies related to cold chain management.
      • The public health nurse at the RHU/health center level typically acts as the Cold Chain Officer.
      • OPV should be stored at -15 to 25°C in a freezer.
      • Other vaccines, such as Measles, MMR, and Rotavirus, are stored in a refrigerator at +2 to +8°C.
      • Hepatitis B, Pentavalent, Rotavirus, and TT are damaged by freezing.
      • Diluted vaccines should be stored in the refrigerator on the lower shelves or door shelves.
    • Other Important Considerations:
      • First-expiry-first-out (FEFO) policy should be followed.
      • Recommended storage and transport durations should be adhered to.
      • VVM should be monitored.
      • The DOH's open-vial policy should be strictly followed.
      • Freeze-dried vaccines should be reconstituted only with the diluents provided.
      • Reconstituted freeze-dried vaccines should be discarded 6 hours after reconstitution or at the end of the immunization session, whichever occurs sooner.
      • BCG should be protected from sunlight, and Rotavirus vaccine should be shielded from light.
    • Side Effects & Adverse Reactions:
      • Vaccine recipients or their guardians should be informed of potential side effects or adverse reactions.

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    Description

    Explore the differences between active and passive immunity in this quiz. Learn about various vaccine types, including live-attenuated, inactivated, and subunit vaccines. Test your understanding of how these components work to protect against disease.

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