Immune System Function and Immunodeficiency Quiz
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Questions and Answers

What is the mechanism by which HIV enters T-helper cells?

  • By binding to the CD4+ receptor and releasing viral RNA into the bloodstream
  • By binding to the CD4+ receptor and inserting viral RNA into the host cell (correct)
  • By binding to the CD8+ receptor and inserting viral RNA into the host cell
  • By binding to the CD8+ receptor and releasing viral RNA into the bloodstream

Which of the following is a characteristic of Type I Immediate Hypersensitivity (Allergy)?

  • Occurs in organs exposed to the environment (correct)
  • Triggers release of cytokines from macrophages
  • Is caused by cytotoxic T cells
  • Stimulates IgA producing plasma cells

What is the result of the decreased thymic hormone levels associated with aging?

  • Stimulation of B-cell proliferation
  • Increase in inflammatory response
  • Enhanced spread of infection
  • Decrease in cell-mediated immunity (correct)

Which of the following represents an effect of stress on the immune system?

<p>Decreased functioning of thymus through secretion of glucocorticoids from adrenal gland (C)</p> Signup and view all the answers

What is the defining characteristic of Acquired Immune Deficiency Syndrome (AIDS) according to CDC guidelines?

<p>CD4+ T-cell count (B)</p> Signup and view all the answers

Which type of immunodeficiency is characterized by moderate to marked reduction in IgA, leading to infections in areas covered with mucosal secretions?

<p>Selective IgE deficiency (D)</p> Signup and view all the answers

What gene defect is associated with Thymic hypoplasia (DiGeorge Syndrome), causing primary T-cell deficiency due to developmental malformation of thymus gland?

<p>Deletion on chromosome 22 (D)</p> Signup and view all the answers

Which type of immunodeficiency is characterized by hypogammaglobulinemia due to blocked maturation of B-cells, resulting in recurrent ear, sinus, and respiratory infections?

<p>Common variable immunodeficiency (C)</p> Signup and view all the answers

What type of immune abnormalities result in abnormal immunoglobulin synthesis or maturation deficiency of immunoglobulin?

<p>B-lymphocyte immune abnormalities (A)</p> Signup and view all the answers

Which type of immunodeficiency is characterized by an inability to clear infections, leading to recurrent ear, sinus, and respiratory infections?

<p>Common variable immunodeficiency (D)</p> Signup and view all the answers

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