Immune System Development and Neonatal Immunology Quiz
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Questions and Answers

When does the development of lymphoid organs and lymphoid cells begin?

  • 7 days postpartum
  • During pregnancy (correct)
  • At birth
  • 15 days postpartum

    • When does antibody production start in foetuses?

  • 15 days postpartum
  • 7 days postpartum (correct)
  • During pregnancy
  • At birth

    • When is immune competence attained in neonates?

  • During pregnancy
  • 15 days postpartum
  • At birth
  • After birth (correct)

    • What is the gestation period mentioned in the text?

    <p>340 days</p> Signup and view all the answers

    What type of placenta is present in horses, cattle, and pigs?

    <p>Epitheliochorial placenta</p> Signup and view all the answers

    What is the main reason for the vulnerability of neonates to infection?

    <p>Immature immune system</p> Signup and view all the answers

    What is the primary function of colostrum in postnatal transfer of immunity?

    <p>Transfer of IgG</p> Signup and view all the answers

    What is the impact of maternal antibodies on neonatal vaccination?

    <p>Block of essential BCR epitopes</p> Signup and view all the answers

    When is immunity fully developed in most species?

    <p>12 months of age</p> Signup and view all the answers

    What is the incubation time for stem cells?

    <p>7 days</p> Signup and view all the answers

    When do IgA-positive B cells develop after hatching?

    <p>1 week after hatching</p> Signup and view all the answers

    What is the transfer of antibodies from the mother to the fetus/neonate called?

    <p>Maternal transfer</p> Signup and view all the answers

    What is the primary function of colostrum in postnatal transfer of immunity?

    <p>Transfer of IgG</p> Signup and view all the answers

    What is the main reason for the vulnerability of neonates to infection?

    <p>Immature immune system</p> Signup and view all the answers

    What is the impact of maternal antibodies on neonatal vaccination?

    <p>Block of essential BCR epitopes</p> Signup and view all the answers

    When does the development of lymphoid organs and lymphoid cells begin?

    <p>During pregnancy</p> Signup and view all the answers

    When is immune competence attained in neonates?

    <p>After birth</p> Signup and view all the answers

    What is the primary function of colostrum in postnatal transfer of immunity?

    <p>Transfer of maternal antibodies</p> Signup and view all the answers

    What is the impact of maternal antibodies on neonatal vaccination?

    <p>Maternal antibodies can block essential BCR epitopes, hindering the endogenous humoral immune response</p> Signup and view all the answers

    What is the primary function of colostrum in postnatal transfer of immunity?

    <p>To transfer maternal antibodies, mainly IgG, to the newborn</p> Signup and view all the answers

    When does antibody production start in foetuses?

    <p>During the last few weeks of gestation</p> Signup and view all the answers

    When is immune competence attained in neonates?

    <p>At 12 months of age</p> Signup and view all the answers

    What type of placenta is present in horses, cattle, and pigs?

    <p>Epitheliochorial placenta</p> Signup and view all the answers

    When is immunity fully developed in most species?

    <p>At 12 months of age</p> Signup and view all the answers

    What is the gestation period mentioned in the text?

    <p>340 days</p> Signup and view all the answers

    When does the development of lymphoid organs and lymphoid cells begin?

    <p>During the last few weeks of gestation</p> Signup and view all the answers

    What is the incubation time for stem cells?

    <p>21 days</p> Signup and view all the answers

    What is the impact of maternal antibodies on neonatal vaccination?

    <p>Maternal antibodies can block essential BCR epitopes, hindering the endogenous humoral immune response</p> Signup and view all the answers

    What happens if a newborn receives only a single vaccination at 10 weeks of age?

    <p>The newborn would not respond to the vaccination</p> Signup and view all the answers

    What is the impact of maternal antibodies on neonatal vaccination?

    <p>Maternal antibodies can block essential BCR epitopes, hindering the endogenous humoral immune response</p> Signup and view all the answers

    When does immune competence develop in neonates?

    <p>After birth, but not at birth</p> Signup and view all the answers

    What is the primary site for lymphocyte development?

    <p>Bone marrow</p> Signup and view all the answers

    When do antibodies start to be produced in foetuses?

    <p>During pregnancy</p> Signup and view all the answers

    What is the incubation time for stem cells?

    <p>90 days</p> Signup and view all the answers

    When do IgA-positive B cells develop after hatching?

    <p>12 days</p> Signup and view all the answers

    What is the gestation period mentioned in the text?

    <p>340 days</p> Signup and view all the answers

    What type of placenta is present in horses, cattle, and pigs?

    <p>Epitheliochorial placenta</p> Signup and view all the answers

    When is immune competence attained in neonates?

    <p>12 months of age</p> Signup and view all the answers

    What happens if a newborn receives only a single vaccination at 10 weeks of age?

    <p>No immune response</p> Signup and view all the answers

    What is the primary function of colostrum in postnatal transfer of immunity?

    <p>Protection against enteric pathogens</p> Signup and view all the answers

    What is the impact of maternal antibodies on neonatal vaccination?

    <p>Block of essential BCR epitopes</p> Signup and view all the answers

    What is the transfer of antibodies from the mother to the fetus/neonate called?

    <p>Passive immunity</p> Signup and view all the answers

    What type of placenta is present in cats and dogs?

    <p>Endotheliochorial placenta</p> Signup and view all the answers

    What is the incubation time for stem cells?

    <p>21 days</p> Signup and view all the answers

    When does antibody production start in foetuses?

    <p>At 10 weeks of gestation</p> Signup and view all the answers

    Study Notes

    Development of Lymphoid Organs and Cells

    • Development of lymphoid organs and lymphoid cells begins around 3-4 weeks of gestation.
    • Stem cells incubate for 10-14 days before differentiating into lymphoid cells.

    Immune Competence

    • Immune competence is attained in neonates around 1-2 weeks after birth.
    • Neonates are vulnerable to infection due to their underdeveloped immune system.

    Antibody Production

    • Antibody production starts in foetuses around 12-14 weeks of gestation.

    Gestation Period

    • The gestation period mentioned in the text is 280-300 days.

    Placenta

    • Horses, cattle, and pigs have a epitheliochorial placenta.
    • Cats and dogs have an endothelial placenta.

    Colostrum and Maternal Antibodies

    • The primary function of colostrum in postnatal transfer of immunity is to provide maternal antibodies to the neonate.
    • Maternal antibodies can interfere with neonatal vaccination, making it less effective.
    • If a newborn receives only a single vaccination at 10 weeks of age, it may not be effective due to the presence of maternal antibodies.

    Transfer of Antibodies

    • The transfer of antibodies from the mother to the fetus/neonate is called passive immunity.

    Lymphocyte Development

    • The primary site for lymphocyte development is the lymphoid organs.

    IgA-Positive B Cells

    • IgA-positive B cells develop after hatching, around 2-3 weeks after birth.

    Immunity Development

    • Immunity is fully developed in most species after 1-2 years of age.

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    Related Documents

    Neonatal Immunity PDF

    Description

    Test your knowledge of immune system ontogeny and neonatal immunology in this quiz. Learn about the development of the immune system in utero, species differences in maternal transfer of immunity, routes of maternal transfer of immunity, effects of its failure, and how neonatal immunity is measured.

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