Immune System Development and Neonatal Immunology Quiz

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Questions and Answers

When does the development of lymphoid organs and lymphoid cells begin?

During pregnancy

When does antibody production start in foetuses?

7 days postpartum

When is immune competence attained in neonates?

After birth

What is the gestation period mentioned in the text?

<p>340 days</p> Signup and view all the answers

What type of placenta is present in horses, cattle, and pigs?

<p>Epitheliochorial placenta</p> Signup and view all the answers

What is the main reason for the vulnerability of neonates to infection?

<p>Immature immune system</p> Signup and view all the answers

What is the primary function of colostrum in postnatal transfer of immunity?

<p>Transfer of IgG</p> Signup and view all the answers

What is the impact of maternal antibodies on neonatal vaccination?

<p>Block of essential BCR epitopes</p> Signup and view all the answers

When is immunity fully developed in most species?

<p>12 months of age</p> Signup and view all the answers

What is the incubation time for stem cells?

<p>7 days</p> Signup and view all the answers

When do IgA-positive B cells develop after hatching?

<p>1 week after hatching</p> Signup and view all the answers

What is the transfer of antibodies from the mother to the fetus/neonate called?

<p>Maternal transfer</p> Signup and view all the answers

What is the primary function of colostrum in postnatal transfer of immunity?

<p>Transfer of IgG</p> Signup and view all the answers

What is the main reason for the vulnerability of neonates to infection?

<p>Immature immune system</p> Signup and view all the answers

What is the impact of maternal antibodies on neonatal vaccination?

<p>Block of essential BCR epitopes</p> Signup and view all the answers

When does the development of lymphoid organs and lymphoid cells begin?

<p>During pregnancy</p> Signup and view all the answers

When is immune competence attained in neonates?

<p>After birth</p> Signup and view all the answers

What is the primary function of colostrum in postnatal transfer of immunity?

<p>Transfer of maternal antibodies</p> Signup and view all the answers

What is the impact of maternal antibodies on neonatal vaccination?

<p>Maternal antibodies can block essential BCR epitopes, hindering the endogenous humoral immune response</p> Signup and view all the answers

What is the primary function of colostrum in postnatal transfer of immunity?

<p>To transfer maternal antibodies, mainly IgG, to the newborn</p> Signup and view all the answers

When does antibody production start in foetuses?

<p>During the last few weeks of gestation</p> Signup and view all the answers

When is immune competence attained in neonates?

<p>At 12 months of age</p> Signup and view all the answers

What type of placenta is present in horses, cattle, and pigs?

<p>Epitheliochorial placenta</p> Signup and view all the answers

When is immunity fully developed in most species?

<p>At 12 months of age</p> Signup and view all the answers

What is the gestation period mentioned in the text?

<p>340 days</p> Signup and view all the answers

When does the development of lymphoid organs and lymphoid cells begin?

<p>During the last few weeks of gestation</p> Signup and view all the answers

What is the incubation time for stem cells?

<p>21 days</p> Signup and view all the answers

What is the impact of maternal antibodies on neonatal vaccination?

<p>Maternal antibodies can block essential BCR epitopes, hindering the endogenous humoral immune response</p> Signup and view all the answers

What happens if a newborn receives only a single vaccination at 10 weeks of age?

<p>The newborn would not respond to the vaccination</p> Signup and view all the answers

What is the impact of maternal antibodies on neonatal vaccination?

<p>Maternal antibodies can block essential BCR epitopes, hindering the endogenous humoral immune response</p> Signup and view all the answers

When does immune competence develop in neonates?

<p>After birth, but not at birth</p> Signup and view all the answers

What is the primary site for lymphocyte development?

<p>Bone marrow</p> Signup and view all the answers

When do antibodies start to be produced in foetuses?

<p>During pregnancy</p> Signup and view all the answers

What is the incubation time for stem cells?

<p>90 days</p> Signup and view all the answers

When do IgA-positive B cells develop after hatching?

<p>12 days</p> Signup and view all the answers

What is the gestation period mentioned in the text?

<p>340 days</p> Signup and view all the answers

What type of placenta is present in horses, cattle, and pigs?

<p>Epitheliochorial placenta</p> Signup and view all the answers

When is immune competence attained in neonates?

<p>12 months of age</p> Signup and view all the answers

What happens if a newborn receives only a single vaccination at 10 weeks of age?

<p>No immune response</p> Signup and view all the answers

What is the primary function of colostrum in postnatal transfer of immunity?

<p>Protection against enteric pathogens</p> Signup and view all the answers

What is the impact of maternal antibodies on neonatal vaccination?

<p>Block of essential BCR epitopes</p> Signup and view all the answers

What is the transfer of antibodies from the mother to the fetus/neonate called?

<p>Passive immunity</p> Signup and view all the answers

What type of placenta is present in cats and dogs?

<p>Endotheliochorial placenta</p> Signup and view all the answers

What is the incubation time for stem cells?

<p>21 days</p> Signup and view all the answers

When does antibody production start in foetuses?

<p>At 10 weeks of gestation</p> Signup and view all the answers

Study Notes

Development of Lymphoid Organs and Cells

  • Development of lymphoid organs and lymphoid cells begins around 3-4 weeks of gestation.
  • Stem cells incubate for 10-14 days before differentiating into lymphoid cells.

Immune Competence

  • Immune competence is attained in neonates around 1-2 weeks after birth.
  • Neonates are vulnerable to infection due to their underdeveloped immune system.

Antibody Production

  • Antibody production starts in foetuses around 12-14 weeks of gestation.

Gestation Period

  • The gestation period mentioned in the text is 280-300 days.

Placenta

  • Horses, cattle, and pigs have a epitheliochorial placenta.
  • Cats and dogs have an endothelial placenta.

Colostrum and Maternal Antibodies

  • The primary function of colostrum in postnatal transfer of immunity is to provide maternal antibodies to the neonate.
  • Maternal antibodies can interfere with neonatal vaccination, making it less effective.
  • If a newborn receives only a single vaccination at 10 weeks of age, it may not be effective due to the presence of maternal antibodies.

Transfer of Antibodies

  • The transfer of antibodies from the mother to the fetus/neonate is called passive immunity.

Lymphocyte Development

  • The primary site for lymphocyte development is the lymphoid organs.

IgA-Positive B Cells

  • IgA-positive B cells develop after hatching, around 2-3 weeks after birth.

Immunity Development

  • Immunity is fully developed in most species after 1-2 years of age.

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