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Immune System Development in Infants

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Why do IgA, IgD, IgE, and IgM not cross the placenta?

They require an antigenic challenge for production

At what age do phagocytic cells (neutrophils and monocytes) reach adult levels in terms of chemotaxis?

7 years

Which immune response does not cross the placenta?

Cellular immunity

Why might fetal T cells become sensitized to antigens that cross the placenta?

Cross-reactivity of antigens with maternal antibodies

Why do infant B cells not respond to infection similar to adult B cells?

Immaturity of their immune system

Test your knowledge on the development of the immune system in infants. Learn about the passive filtering of plasma, cellular immunity, and the transfer of antibodies across the placenta.

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