Immune System Deficiencies Quiz

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31 Questions

Which organism can cause severe necrotizing pneumococcal infections in individuals with mutations in MYD88?

Streptococcus pneumoniae

What defect increases the risk for pneumonias caused by encapsulated organisms such as pneumococcus and H.influenzae?

Defects in IgA production

Which factor compromises mucociliary clearance and pulmonary macrophage activity, increasing the risk for aspiration?

Cigarette smoke

In which clinical settings does Streptococcus pneumoniae show an increased frequency?

Chronic diseases such as CHF, COPD, or diabetes

What type of vaccines containing capsular polysaccharides are used in individuals at high risk for pneumococcal sepsis?

Pneumococcal vaccines

Which organism can cause a particularly life-threatening form of pneumonia in children, often after a respiratory viral infection?

Encapsulated Haemophilus influenzae

Which bacterial 2nd most common cause of acute exacerbations of COPD is the most common in adults?

Moraxella catarrhalis

What is one of the three most frequent causes of otitis media in children?

Haemophilus influenzae

Which bacterium is an important cause of secondary bacterial pneumonia in children and healthy adults after viral respiratory illnesses?

Staphylococcus aureus

Which bacterium has a propensity to invade blood vessels at the site of infection, leading to secondary coagulative necrosis of the pulmonary parenchyma?

Pseudomonas aeruginosa

Which bacterium causes Pontiac fever, a self-limited upper-respiratory tract infection without pneumonic symptoms?

Legionella pneumophila

Which bacteria are among the three most frequent causes of otitis media in children?

Haemophilus influenzae and Strep. pneumonia

Which bacteria are associated with infections in cystic fibrosis and most commonly seen in nosocomial settings?

Klebsiella pneumoniae and Pseudomonas aeruginosa

Which bacterium is the most common bacterial cause of acute exacerbations of COPD in adults?

Haemophilus influenzae

Which bacterial infection is associated with a fatality rate of 30% to 50% in immunosuppressed individuals?

Legionella pneumophila infection

Which bacteria can cause a particularly life-threatening form of pneumonia in children, often after a respiratory viral infection?

Haemophilus influenzae

What factor compromises mucociliary clearance and pulmonary macrophage activity, increasing the risk for aspiration?

Cigarette smoke

Which bacteria are among the three most frequent causes of otitis media in children?

Haemophilus influenzae

Which organism can cause severe necrotizing pneumococcal infections in individuals with mutations in MYD88?

Streptococcus pneumoniae

In which clinical settings does Streptococcus pneumoniae show an increased frequency?

Chronic heart failure (CHF), chronic obstructive pulmonary disease (COPD), or diabetes

Which bacterium is an important cause of secondary bacterial pneumonia in children and healthy adults after viral respiratory illnesses?

Streptococcus pneumoniae

Which bacterial infection is associated with right-sided staphylococcal endocarditis as a serious complication of intravenous drug abuse?

Staphylococcus aureus

Which bacterium shows a propensity to invade blood vessels at the site of infection, leading to secondary coagulative necrosis of the pulmonary parenchyma?

Pseudomonas aeruginosa

Which bacteria are among the three most frequent causes of otitis media in children?

H. influenzae, M. catarrhalis, S. pneumoniae

Which bacterium is the most common bacterial cause of acute exacerbations of COPD in adults?

Moraxella catarrhalis

Which bacterial infection is associated with a fatality rate of 30% to 50% in immunosuppressed individuals?

Pseudomonas aeruginosa

Which bacteria are associated with infections in cystic fibrosis and most commonly seen in nosocomial settings?

Klebsiella pneumoniae, Pseudomonas aeruginosa

What bacterium is an important cause of secondary bacterial pneumonia in children and healthy adults after viral respiratory illnesses?

Moraxella catarrhalis

Where is Moraxella catarrhalis positioned among the three most frequent causes of otitis media in children?

Second position

Which organism is the most common bacterial cause of acute exacerbations of COPD in adults?

Moraxella catarrhalis

Which bacterial infection causes Pontiac fever, a self-limited upper-respiratory tract infection without pneumonic symptoms?

Legionella pneumophila

Test your knowledge of immune system deficiencies and their effects on susceptibility to infections. This quiz covers mutations in MYD88, congenital defects in IgA production, compromises caused by cigarette smoke, and impairments due to alcohol consumption.

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