Immune System Deficiencies Quiz

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Questions and Answers

Which organism can cause severe necrotizing pneumococcal infections in individuals with mutations in MYD88?

  • Mycobacterium tuberculosis
  • Streptococcus pneumoniae (correct)
  • Neisseria meningitidis
  • Haemophilus influenzae

What defect increases the risk for pneumonias caused by encapsulated organisms such as pneumococcus and H.influenzae?

  • Neutrophil function impairment
  • TH1 cell–mediated immunity defects
  • Splenic function decrease
  • Defects in IgA production (correct)

Which factor compromises mucociliary clearance and pulmonary macrophage activity, increasing the risk for aspiration?

  • Chronic diseases
  • Alcohol
  • Neutrophile function impairment
  • Cigarette smoke (correct)

In which clinical settings does Streptococcus pneumoniae show an increased frequency?

<p>Chronic diseases such as CHF, COPD, or diabetes (B)</p> Signup and view all the answers

What type of vaccines containing capsular polysaccharides are used in individuals at high risk for pneumococcal sepsis?

<p>Pneumococcal vaccines (B)</p> Signup and view all the answers

Which organism can cause a particularly life-threatening form of pneumonia in children, often after a respiratory viral infection?

<p>Encapsulated Haemophilus influenzae (D)</p> Signup and view all the answers

Which bacterial 2nd most common cause of acute exacerbations of COPD is the most common in adults?

<p>Moraxella catarrhalis (B)</p> Signup and view all the answers

What is one of the three most frequent causes of otitis media in children?

<p>Haemophilus influenzae (A)</p> Signup and view all the answers

Which bacterium is an important cause of secondary bacterial pneumonia in children and healthy adults after viral respiratory illnesses?

<p>Staphylococcus aureus (B)</p> Signup and view all the answers

Which bacterium has a propensity to invade blood vessels at the site of infection, leading to secondary coagulative necrosis of the pulmonary parenchyma?

<p>Pseudomonas aeruginosa (C)</p> Signup and view all the answers

Which bacterium causes Pontiac fever, a self-limited upper-respiratory tract infection without pneumonic symptoms?

<p>Legionella pneumophila (A)</p> Signup and view all the answers

Which bacteria are among the three most frequent causes of otitis media in children?

<p>Haemophilus influenzae and Strep. pneumonia (C)</p> Signup and view all the answers

Which bacteria are associated with infections in cystic fibrosis and most commonly seen in nosocomial settings?

<p>Klebsiella pneumoniae and Pseudomonas aeruginosa (D)</p> Signup and view all the answers

Which bacterium is the most common bacterial cause of acute exacerbations of COPD in adults?

<p>Haemophilus influenzae (A)</p> Signup and view all the answers

Which bacterial infection is associated with a fatality rate of 30% to 50% in immunosuppressed individuals?

<p>Legionella pneumophila infection (D)</p> Signup and view all the answers

Which bacteria can cause a particularly life-threatening form of pneumonia in children, often after a respiratory viral infection?

<p>Haemophilus influenzae (C)</p> Signup and view all the answers

What factor compromises mucociliary clearance and pulmonary macrophage activity, increasing the risk for aspiration?

<p>Cigarette smoke (A)</p> Signup and view all the answers

Which bacteria are among the three most frequent causes of otitis media in children?

<p>Haemophilus influenzae (A)</p> Signup and view all the answers

Which organism can cause severe necrotizing pneumococcal infections in individuals with mutations in MYD88?

<p>Streptococcus pneumoniae (C)</p> Signup and view all the answers

In which clinical settings does Streptococcus pneumoniae show an increased frequency?

<p>Chronic heart failure (CHF), chronic obstructive pulmonary disease (COPD), or diabetes (D)</p> Signup and view all the answers

Which bacterium is an important cause of secondary bacterial pneumonia in children and healthy adults after viral respiratory illnesses?

<p>Streptococcus pneumoniae (A)</p> Signup and view all the answers

Which bacterial infection is associated with right-sided staphylococcal endocarditis as a serious complication of intravenous drug abuse?

<p>Staphylococcus aureus (A)</p> Signup and view all the answers

Which bacterium shows a propensity to invade blood vessels at the site of infection, leading to secondary coagulative necrosis of the pulmonary parenchyma?

<p>Pseudomonas aeruginosa (B)</p> Signup and view all the answers

Which bacteria are among the three most frequent causes of otitis media in children?

<p>H. influenzae, M. catarrhalis, S. pneumoniae (A)</p> Signup and view all the answers

Which bacterium is the most common bacterial cause of acute exacerbations of COPD in adults?

<p>Moraxella catarrhalis (C)</p> Signup and view all the answers

Which bacterial infection is associated with a fatality rate of 30% to 50% in immunosuppressed individuals?

<p>Pseudomonas aeruginosa (D)</p> Signup and view all the answers

Which bacteria are associated with infections in cystic fibrosis and most commonly seen in nosocomial settings?

<p>Klebsiella pneumoniae, Pseudomonas aeruginosa (D)</p> Signup and view all the answers

What bacterium is an important cause of secondary bacterial pneumonia in children and healthy adults after viral respiratory illnesses?

<p>Moraxella catarrhalis (A)</p> Signup and view all the answers

Where is Moraxella catarrhalis positioned among the three most frequent causes of otitis media in children?

<p>Second position (C)</p> Signup and view all the answers

Which organism is the most common bacterial cause of acute exacerbations of COPD in adults?

<p>Moraxella catarrhalis (D)</p> Signup and view all the answers

Which bacterial infection causes Pontiac fever, a self-limited upper-respiratory tract infection without pneumonic symptoms?

<p>Legionella pneumophila (B)</p> Signup and view all the answers

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