Immune System Deficiencies Quiz
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Questions and Answers

Which organism can cause severe necrotizing pneumococcal infections in individuals with mutations in MYD88?

  • Mycobacterium tuberculosis
  • Streptococcus pneumoniae (correct)
  • Neisseria meningitidis
  • Haemophilus influenzae
  • What defect increases the risk for pneumonias caused by encapsulated organisms such as pneumococcus and H.influenzae?

  • Neutrophil function impairment
  • TH1 cell–mediated immunity defects
  • Splenic function decrease
  • Defects in IgA production (correct)
  • Which factor compromises mucociliary clearance and pulmonary macrophage activity, increasing the risk for aspiration?

  • Chronic diseases
  • Alcohol
  • Neutrophile function impairment
  • Cigarette smoke (correct)
  • In which clinical settings does Streptococcus pneumoniae show an increased frequency?

    <p>Chronic diseases such as CHF, COPD, or diabetes</p> Signup and view all the answers

    What type of vaccines containing capsular polysaccharides are used in individuals at high risk for pneumococcal sepsis?

    <p>Pneumococcal vaccines</p> Signup and view all the answers

    Which organism can cause a particularly life-threatening form of pneumonia in children, often after a respiratory viral infection?

    <p>Encapsulated Haemophilus influenzae</p> Signup and view all the answers

    Which bacterial 2nd most common cause of acute exacerbations of COPD is the most common in adults?

    <p>Moraxella catarrhalis</p> Signup and view all the answers

    What is one of the three most frequent causes of otitis media in children?

    <p>Haemophilus influenzae</p> Signup and view all the answers

    Which bacterium is an important cause of secondary bacterial pneumonia in children and healthy adults after viral respiratory illnesses?

    <p>Staphylococcus aureus</p> Signup and view all the answers

    Which bacterium has a propensity to invade blood vessels at the site of infection, leading to secondary coagulative necrosis of the pulmonary parenchyma?

    <p>Pseudomonas aeruginosa</p> Signup and view all the answers

    Which bacterium causes Pontiac fever, a self-limited upper-respiratory tract infection without pneumonic symptoms?

    <p>Legionella pneumophila</p> Signup and view all the answers

    Which bacteria are among the three most frequent causes of otitis media in children?

    <p>Haemophilus influenzae and Strep. pneumonia</p> Signup and view all the answers

    Which bacteria are associated with infections in cystic fibrosis and most commonly seen in nosocomial settings?

    <p>Klebsiella pneumoniae and Pseudomonas aeruginosa</p> Signup and view all the answers

    Which bacterium is the most common bacterial cause of acute exacerbations of COPD in adults?

    <p>Haemophilus influenzae</p> Signup and view all the answers

    Which bacterial infection is associated with a fatality rate of 30% to 50% in immunosuppressed individuals?

    <p>Legionella pneumophila infection</p> Signup and view all the answers

    Which bacteria can cause a particularly life-threatening form of pneumonia in children, often after a respiratory viral infection?

    <p>Haemophilus influenzae</p> Signup and view all the answers

    What factor compromises mucociliary clearance and pulmonary macrophage activity, increasing the risk for aspiration?

    <p>Cigarette smoke</p> Signup and view all the answers

    Which bacteria are among the three most frequent causes of otitis media in children?

    <p>Haemophilus influenzae</p> Signup and view all the answers

    Which organism can cause severe necrotizing pneumococcal infections in individuals with mutations in MYD88?

    <p>Streptococcus pneumoniae</p> Signup and view all the answers

    In which clinical settings does Streptococcus pneumoniae show an increased frequency?

    <p>Chronic heart failure (CHF), chronic obstructive pulmonary disease (COPD), or diabetes</p> Signup and view all the answers

    Which bacterium is an important cause of secondary bacterial pneumonia in children and healthy adults after viral respiratory illnesses?

    <p>Streptococcus pneumoniae</p> Signup and view all the answers

    Which bacterial infection is associated with right-sided staphylococcal endocarditis as a serious complication of intravenous drug abuse?

    <p>Staphylococcus aureus</p> Signup and view all the answers

    Which bacterium shows a propensity to invade blood vessels at the site of infection, leading to secondary coagulative necrosis of the pulmonary parenchyma?

    <p>Pseudomonas aeruginosa</p> Signup and view all the answers

    Which bacteria are among the three most frequent causes of otitis media in children?

    <p>H. influenzae, M. catarrhalis, S. pneumoniae</p> Signup and view all the answers

    Which bacterium is the most common bacterial cause of acute exacerbations of COPD in adults?

    <p>Moraxella catarrhalis</p> Signup and view all the answers

    Which bacterial infection is associated with a fatality rate of 30% to 50% in immunosuppressed individuals?

    <p>Pseudomonas aeruginosa</p> Signup and view all the answers

    Which bacteria are associated with infections in cystic fibrosis and most commonly seen in nosocomial settings?

    <p>Klebsiella pneumoniae, Pseudomonas aeruginosa</p> Signup and view all the answers

    What bacterium is an important cause of secondary bacterial pneumonia in children and healthy adults after viral respiratory illnesses?

    <p>Moraxella catarrhalis</p> Signup and view all the answers

    Where is Moraxella catarrhalis positioned among the three most frequent causes of otitis media in children?

    <p>Second position</p> Signup and view all the answers

    Which organism is the most common bacterial cause of acute exacerbations of COPD in adults?

    <p>Moraxella catarrhalis</p> Signup and view all the answers

    Which bacterial infection causes Pontiac fever, a self-limited upper-respiratory tract infection without pneumonic symptoms?

    <p>Legionella pneumophila</p> Signup and view all the answers

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