24 Questions
What is the primary purpose of a 'good' amount of inflammation in response to an infection?
To get the immune system going
What is a characteristic of the innate immune system's response to a microbe?
It responds the same way each time a microbe is encountered
What can occur when the innate immune responses fail to contain a pathogen?
The pathogen may spread and initiate an adaptive immune response
Which of the following diseases is NOT associated with chronic inflammation?
Hypertension
What is unique about David Vetter's immune system?
He had to rely almost entirely on innate immunity
What is a hallmark of the innate immune system?
Speed
What is the role of innate immune cells in relation to inflammation?
They cause inflammation
What is the consequence of too much inflammation?
It may lead to death
Which type of cell lineage does a neutrophil belong to?
Common Myeloid Progenitor
What is one of the hallmarks of the innate immune system regarding its response to repeated exposure to the same microbe?
Repetitive
Which component of innate immunity includes tumor necrosis factor (TNF)?
Cytokines
Which cells are not part of the innate immune system?
Lymphocytes
Where do immune cells originate?
Bone marrow
Through what mechanism can the innate immune system differentiate between self and non-self?
Expression of distinct patterns on microbes
Which immune system characteristic is predominantly associated with a rapid and early response?
Innate immune system
What is one way that epithelial barriers function within innate immunity?
Forming physical barriers
Which molecule is primarily responsible for attracting neutrophils to sites of inflammation?
Chemokines
What is the immediate effect of histamine release during inflammation?
Dilation of blood vessels
Which cells are primarily recruited first to sites of sterile tissue injury?
Neutrophils
What role do adhesion molecules play during the inflammatory response?
Facilitating the binding of immune cells to endothelial cells
What type of immune cells are carried into inflamed tissue along with plasma proteins?
Innate immune cells
How do different cells respond to different chemokines?
By expressing different chemokine receptors
What induces the expression of adhesion molecules on endothelial cells?
Histamine and inflammatory cytokines
Which of the following is NOT a direct effect of blood vessel dilation during inflammation?
Inducing chemokine receptors
This quiz covers the anatomy of the immune system, including the origin of immune cells, primary and secondary lymphoid organs, and the different types of immune cells.
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