9 Questions
Which receptor on naive T cells is preferentially engaged by dendritic cells that capture tumor antigens?
CTLA-4
What is the function of myeloid-derived suppressor cells in tumors?
Secrete immunosuppressive cytokines
Which cytokine may be secreted by some tumors to induce immunosuppression?
Transforming growth factor β
Which of the following is a mechanism used by tumors to avoid destruction by the immune system?
Expression of PD-L1
Why do immune responses often fail to check tumor growth?
Tumors do not display antigens to CD8+ T cells
Why do T cells specific for tumor antigens become unresponsive to antigen?
They develop an exhausted state
Which mechanism do tumors use to avoid destruction by the immune system?
Tumors stop expressing class I MHC molecules
Why do immune responses often fail to check tumor growth?
Tumors grow rapidly
What happens to T cells when they are repeatedly stimulated by persistent tumors?
T cells develop an exhausted state
Test your knowledge on immune responses and tumor growth with this quiz. Learn about the challenges the immune system faces in combating malignant tumors and how tumors can evade immune recognition. Understand why immune responses may fail to check tumor growth and why tumors can grow rapidly.
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