Immune Response Cytokines
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Questions and Answers

What is the primary role of IL-1?

  • Upregulates RNase activity to control viral infection
  • Stimulates acute-phase protein synthesis
  • Upregulates inflammatory response, including fever (correct)
  • Enhances antigen recognition by T and B cells

Which cells are the primary source of IL-2?

  • T cells (correct)
  • All somatic cells
  • Monocytes and macrophages
  • Macrophages and dendritic cells

What is the role of IL-4 in the immune response?

  • Stimulates IL-1, IL-6, TNF, and chemokine production
  • T-cell subset and mast cells (correct)
  • Enhances antigen recognition by T and B cells
  • Upregulates inflammatory response, including fever

Which cytokine is involved in hematopoiesis and is produced by bone marrow and thymic stromal cells?

<p>IL-7 (A)</p> Signup and view all the answers

What is the primary role of IFN-α?

<p>Upregulates RNase activity to control viral infection (A)</p> Signup and view all the answers

Which cytokine is produced by macrophages and dendritic cells and plays a key role in innate resistance?

<p>IL-23 (B)</p> Signup and view all the answers

What is the primary role of TNF-β?

<p>Induces tumor regression (A)</p> Signup and view all the answers

Which cytokine is involved in innate resistance and is produced by all somatic cells?

<p>IFN-α (B)</p> Signup and view all the answers

What is the primary role of CSF-1?

<p>Stimulates osteoblasts (A)</p> Signup and view all the answers

What effect does IL-4 have on B cells?

<p>Stimulates growth of B cells (A)</p> Signup and view all the answers

What is the primary function of IL-1?

<p>Induces pro-inflammatory cytokines (B)</p> Signup and view all the answers

What is the effect of IL-5 on eosinophils?

<p>Activates eosinophils (B)</p> Signup and view all the answers

What is the primary function of IL-2?

<p>Stimulates growth and function of T-cell subsets (A)</p> Signup and view all the answers

What is the effect of IL-7 on hematopoietic stem cells?

<p>Stimulates pluripotent hematopoietic stem cells to become lymphoid progenitor cells (A)</p> Signup and view all the answers

What is the primary function of IL-3?

<p>Stimulates pluripotent hematopoietic stem cells to become myeloid progenitor cells (A)</p> Signup and view all the answers

What is the effect of IL-12 on the immune system?

<p>Inhibits IL-12 production (D)</p> Signup and view all the answers

What is the primary function of GM-CSF?

<p>Induces hematopoietic stem cells to proliferate and differentiate into granulocytes and monocytes (B)</p> Signup and view all the answers

What is the effect of G-CSF on hematopoietic stem cells?

<p>Induces hematopoietic stem cells to proliferate and differentiate into neutrophils (D)</p> Signup and view all the answers

What is the primary function of M-CSF?

<p>Induces hematopoietic stem cells to proliferate and differentiate into monocytes/macrophages (C)</p> Signup and view all the answers

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