Immune Response Cytokines
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Questions and Answers

What is the primary role of IL-1?

  • Upregulates RNase activity to control viral infection
  • Stimulates acute-phase protein synthesis
  • Upregulates inflammatory response, including fever (correct)
  • Enhances antigen recognition by T and B cells

    • Which cells are the primary source of IL-2?

  • T cells (correct)
  • All somatic cells
  • Monocytes and macrophages
  • Macrophages and dendritic cells

    • What is the role of IL-4 in the immune response?

  • Stimulates IL-1, IL-6, TNF, and chemokine production
  • T-cell subset and mast cells (correct)
  • Enhances antigen recognition by T and B cells
  • Upregulates inflammatory response, including fever

    • Which cytokine is involved in hematopoiesis and is produced by bone marrow and thymic stromal cells?

    <p>IL-7</p> Signup and view all the answers

    What is the primary role of IFN-α?

    <p>Upregulates RNase activity to control viral infection</p> Signup and view all the answers

    Which cytokine is produced by macrophages and dendritic cells and plays a key role in innate resistance?

    <p>IL-23</p> Signup and view all the answers

    What is the primary role of TNF-β?

    <p>Induces tumor regression</p> Signup and view all the answers

    Which cytokine is involved in innate resistance and is produced by all somatic cells?

    <p>IFN-α</p> Signup and view all the answers

    What is the primary role of CSF-1?

    <p>Stimulates osteoblasts</p> Signup and view all the answers

    What effect does IL-4 have on B cells?

    <p>Stimulates growth of B cells</p> Signup and view all the answers

    What is the primary function of IL-1?

    <p>Induces pro-inflammatory cytokines</p> Signup and view all the answers

    What is the effect of IL-5 on eosinophils?

    <p>Activates eosinophils</p> Signup and view all the answers

    What is the primary function of IL-2?

    <p>Stimulates growth and function of T-cell subsets</p> Signup and view all the answers

    What is the effect of IL-7 on hematopoietic stem cells?

    <p>Stimulates pluripotent hematopoietic stem cells to become lymphoid progenitor cells</p> Signup and view all the answers

    What is the primary function of IL-3?

    <p>Stimulates pluripotent hematopoietic stem cells to become myeloid progenitor cells</p> Signup and view all the answers

    What is the effect of IL-12 on the immune system?

    <p>Inhibits IL-12 production</p> Signup and view all the answers

    What is the primary function of GM-CSF?

    <p>Induces hematopoietic stem cells to proliferate and differentiate into granulocytes and monocytes</p> Signup and view all the answers

    What is the effect of G-CSF on hematopoietic stem cells?

    <p>Induces hematopoietic stem cells to proliferate and differentiate into neutrophils</p> Signup and view all the answers

    What is the primary function of M-CSF?

    <p>Induces hematopoietic stem cells to proliferate and differentiate into monocytes/macrophages</p> Signup and view all the answers

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