Immune Response and Inflammation
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Questions and Answers

What is the primary function of T cells in the body?

  • To survey the body for foreign antigens and preferentially home to sites of microbial invasion (correct)
  • To form immunoglobulin class switching
  • To produce antibodies
  • To trap antigens in follicular dendritic cells

Which type of cells predominantly populate the blood?

  • NK cells
  • T cells (correct)
  • Dendritic cells
  • B cells

What is the main difference between the two routes of lymphocyte circulation?

  • The speed of lymphocyte circulation
  • The presence of HEVs
  • The type of lymphocytes involved
  • The route of entry into lymph nodes (correct)

What is the function of HEVs in lymph nodes?

<p>To allow lymphocytes to pass easily (A)</p> Signup and view all the answers

What is the composition of afferent lymph?

<p>85% T cells, 5% B cells, 10% dendritic cells (D)</p> Signup and view all the answers

Which type of cells are involved in the formation of immunoglobulin class switching?

<p>B cells (A)</p> Signup and view all the answers

What is the primary function of Lymphoid Tissue Inducer cells?

<p>Developing early innate immunity to parasitic helminths (C)</p> Signup and view all the answers

Which type of ILC cell is associated with the production of IL-5, IL-13, and smaller amounts of IL-4 and IL-9?

<p>ILC2 cells (D)</p> Signup and view all the answers

What is the primary function of NK cells?

<p>Killing virus-infected and tumor cells without prior activation (C)</p> Signup and view all the answers

Which type of ILC cell is similar to Th17 cells in their cytokine profile?

<p>Group 3 ILC cells (D)</p> Signup and view all the answers

What is the characteristic of ILC1 cells?

<p>Being cytotoxic and able to kill virus-infected cells (D)</p> Signup and view all the answers

Where are Group 3 ILC cells typically found?

<p>Gut tract and lungs (A)</p> Signup and view all the answers

What is the primary function of ILC1 cells?

<p>Defense against viruses and intracellular bacteria and parasites (B)</p> Signup and view all the answers

Which type of cells are closely related to ILCs?

<p>NK cells (A)</p> Signup and view all the answers

What is the primary function of ILC2 cells?

<p>Defense against helminths (C)</p> Signup and view all the answers

What is the effect of IL-23, IL-1B, and retinoic acid on ILCs?

<p>Differentiation into ILC3 cells (A)</p> Signup and view all the answers

What is the effect of IL-12, IL-15, and IL-18 on ILCs?

<p>Differentiation into ILC1 cells (C)</p> Signup and view all the answers

What is a characteristic of lymphocyte cells?

<p>Small round cells, 7 to 10 μm in diameter (A)</p> Signup and view all the answers

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