Immune Response and Inflammation
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Questions and Answers

What is the primary function of T cells in the body?

  • To survey the body for foreign antigens and preferentially home to sites of microbial invasion (correct)
  • To form immunoglobulin class switching
  • To produce antibodies
  • To trap antigens in follicular dendritic cells

    • Which type of cells predominantly populate the blood?

  • NK cells
  • T cells (correct)
  • Dendritic cells
  • B cells

    • What is the main difference between the two routes of lymphocyte circulation?

  • The speed of lymphocyte circulation
  • The presence of HEVs
  • The type of lymphocytes involved
  • The route of entry into lymph nodes (correct)

    • What is the function of HEVs in lymph nodes?

    <p>To allow lymphocytes to pass easily</p> Signup and view all the answers

    What is the composition of afferent lymph?

    <p>85% T cells, 5% B cells, 10% dendritic cells</p> Signup and view all the answers

    Which type of cells are involved in the formation of immunoglobulin class switching?

    <p>B cells</p> Signup and view all the answers

    What is the primary function of Lymphoid Tissue Inducer cells?

    <p>Developing early innate immunity to parasitic helminths</p> Signup and view all the answers

    Which type of ILC cell is associated with the production of IL-5, IL-13, and smaller amounts of IL-4 and IL-9?

    <p>ILC2 cells</p> Signup and view all the answers

    What is the primary function of NK cells?

    <p>Killing virus-infected and tumor cells without prior activation</p> Signup and view all the answers

    Which type of ILC cell is similar to Th17 cells in their cytokine profile?

    <p>Group 3 ILC cells</p> Signup and view all the answers

    What is the characteristic of ILC1 cells?

    <p>Being cytotoxic and able to kill virus-infected cells</p> Signup and view all the answers

    Where are Group 3 ILC cells typically found?

    <p>Gut tract and lungs</p> Signup and view all the answers

    What is the primary function of ILC1 cells?

    <p>Defense against viruses and intracellular bacteria and parasites</p> Signup and view all the answers

    Which type of cells are closely related to ILCs?

    <p>NK cells</p> Signup and view all the answers

    What is the primary function of ILC2 cells?

    <p>Defense against helminths</p> Signup and view all the answers

    What is the effect of IL-23, IL-1B, and retinoic acid on ILCs?

    <p>Differentiation into ILC3 cells</p> Signup and view all the answers

    What is the effect of IL-12, IL-15, and IL-18 on ILCs?

    <p>Differentiation into ILC1 cells</p> Signup and view all the answers

    What is a characteristic of lymphocyte cells?

    <p>Small round cells, 7 to 10 μm in diameter</p> Signup and view all the answers

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