18 Questions
What is the primary function of T cells in the body?
To survey the body for foreign antigens and preferentially home to sites of microbial invasion
Which type of cells predominantly populate the blood?
T cells
What is the main difference between the two routes of lymphocyte circulation?
The route of entry into lymph nodes
What is the function of HEVs in lymph nodes?
To allow lymphocytes to pass easily
What is the composition of afferent lymph?
85% T cells, 5% B cells, 10% dendritic cells
Which type of cells are involved in the formation of immunoglobulin class switching?
B cells
What is the primary function of Lymphoid Tissue Inducer cells?
Developing early innate immunity to parasitic helminths
Which type of ILC cell is associated with the production of IL-5, IL-13, and smaller amounts of IL-4 and IL-9?
ILC2 cells
What is the primary function of NK cells?
Killing virus-infected and tumor cells without prior activation
Which type of ILC cell is similar to Th17 cells in their cytokine profile?
Group 3 ILC cells
What is the characteristic of ILC1 cells?
Being cytotoxic and able to kill virus-infected cells
Where are Group 3 ILC cells typically found?
Gut tract and lungs
What is the primary function of ILC1 cells?
Defense against viruses and intracellular bacteria and parasites
Which type of cells are closely related to ILCs?
NK cells
What is the primary function of ILC2 cells?
Defense against helminths
What is the effect of IL-23, IL-1B, and retinoic acid on ILCs?
Differentiation into ILC3 cells
What is the effect of IL-12, IL-15, and IL-18 on ILCs?
Differentiation into ILC1 cells
What is a characteristic of lymphocyte cells?
Small round cells, 7 to 10 μm in diameter
This quiz covers the functions of a specific type of immune cell, including its response to thymic stromal lymphopoietin, regulation of type 2 inflammatory responses, and roles in asthma and allergic diseases. Learn about the cytokines involved and the cell's effects on eosinophil production, mucus production, and tissue repair.
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