Hypothalamus and Pituitary Gland

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Questions and Answers

Which function is primarily associated with the hypothalamus?

  • Regulation of blood calcium levels
  • Filtering sensory information for conscious perception
  • Direct control of muscle movement
  • Regulation of body temperature (correct)

The hypothalamus influences the pituitary gland's function by:

  • Directly stimulating hormone release from target tissues
  • Transmitting electrical signals through spinal nerves
  • Filtering toxins from the bloodstream
  • Secreting releasing and inhibiting hormones into the portal system (correct)

What anatomical structure houses the pituitary gland?

  • Sphenoid sinus
  • Sella turcica (correct)
  • Foramen magnum
  • Cribriform plate

How do the anterior and posterior pituitary glands differ in terms of hypothalamic control?

<p>The anterior pituitary synthesizes its own hormones, while the posterior pituitary stores hormones synthesized by the hypothalamus. (A)</p> Signup and view all the answers

Which of the following best describes the hypophyseal portal system's function?

<p>It transports hormones from the hypothalamus to the anterior pituitary. (B)</p> Signup and view all the answers

Which hormones are synthesized in the hypothalamus and stored in the posterior pituitary?

<p>ADH and oxytocin (D)</p> Signup and view all the answers

What is the primary mechanism by which ADH and oxytocin are transported from the hypothalamus to the posterior pituitary?

<p>Along nerve axons (D)</p> Signup and view all the answers

The release of hormones from the anterior pituitary is primarily controlled by:

<p>Releasing and inhibiting hormones from the hypothalamus (C)</p> Signup and view all the answers

What is the role of parvicellular neurosecretory cells in the context of the anterior pituitary function?

<p>Secretion of releasing hormones into the hypophyseal portal system (D)</p> Signup and view all the answers

Which of the following hormones is NOT directly produced by the anterior pituitary?

<p>Antidiuretic hormone (ADH) (A)</p> Signup and view all the answers

Thyrotropin-releasing hormone (TRH) primarily stimulates the secretion of which hormone from the anterior pituitary?

<p>Thyroid-stimulating hormone (TSH) (B)</p> Signup and view all the answers

What is the primary effect of Growth hormone-inhibiting hormone (somatostatin) on the anterior pituitary?

<p>Inhibits the release of growth hormone (D)</p> Signup and view all the answers

Which anterior pituitary cell type is responsible for producing adrenocorticotropic hormone (ACTH)?

<p>Corticotropes (B)</p> Signup and view all the answers

Which of the following statements best describes the action of anterior pituitary hormones?

<p>They act on specific membrane receptors on target tissues. (A)</p> Signup and view all the answers

What role does the Prolactin-inhibiting hormone (PIH), mainly dopamine, play in prolactin regulation?

<p>Inhibits prolactin secretion (A)</p> Signup and view all the answers

Which of the following is an effect of prolactin in females?

<p>Stimulation of milk production (C)</p> Signup and view all the answers

During pregnancy, why does lactation not typically occur despite elevated prolactin levels?

<p>High levels of progesterone interfere with prolactin action (A)</p> Signup and view all the answers

Which of the following is known to stimulate prolactin secretion?

<p>Suckling (B)</p> Signup and view all the answers

What is the effect of prolactin on GnRH secretion?

<p>Inhibits GnRH secretion (B)</p> Signup and view all the answers

Besides prolactin, which hormone(s) are known to have galactopoietic effects (maintain established milk production)?

<p>Cortisol and other metabolic hormones permissively (A)</p> Signup and view all the answers

Damage to the hypophyseal portal system would most directly affect the function of the:

<p>Anterior Pituitary (A)</p> Signup and view all the answers

Which hypothalamic nucleus is most directly involved in the production of hormones stored and released by the posterior pituitary?

<p>Supraoptic and Paraventricular nuclei (B)</p> Signup and view all the answers

Which of the following anterior pituitary hormones directly stimulates the adrenal cortex?

<p>ACTH (B)</p> Signup and view all the answers

Which factors can act as Prolactin-Releasing Factors (PRFs)?

<p>Thyrotropin-releasing hormone (TRH), angiotensin II, substance P, and β endorphin (C)</p> Signup and view all the answers

How does estradiol modulate prolactin release?

<p>Increases the sensitivity of the lactotroph to stimulation by TRH and decreases the sensitivity of the lactotroph to inhibition by DA (B)</p> Signup and view all the answers

During the suckling reflex, what is the role of spinal cord neurons in regulating prolactin release?

<p>They inhibit dopamine release from the arcuate nucleus, leading to increased prolactin secretion. (C)</p> Signup and view all the answers

Which of the following is a consequence of prolactin's inhibition of GnRH release?

<p>Lactational amenorrhea (A)</p> Signup and view all the answers

Considering the interplay between the hypothalamus and pituitary, which of the following scenarios would most likely result in decreased TSH secretion?

<p>Chronic overproduction of thyroid hormones (C)</p> Signup and view all the answers

Which hormone is NOT involved in Mammogenesis?

<p>AVP (1% to 20% as powerful as OT) (C)</p> Signup and view all the answers

Flashcards

What is the hypothalamus?

The control center for homeostasis in the body.

What is the pituitary gland?

The master gland, weighing 500-900 mg, regulated by the hypothalamus and located in the sella turcica.

What is the adenohypophysis?

The anterior lobe of the pituitary gland.

What is the neurohypophysis?

The posterior lobe of the pituitary gland.

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What is the pituitary stalk?

The stalk containing blood vessels and nerve fibers connecting the hypothalamus and pituitary gland.

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What controls the posterior pituitary?

Hormone secretion controlled by Supraoptic and paraventricular nuclei.

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What hormones come from the posterior pituitary?

Synthesized in the hypothalamus, then stored and released from the posterior pituitary. Includes oxytocin and ADH.

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What is the hypothalamo-hypophysial portal system?

A system of blood vessels connecting the hypothalamus and anterior pituitary for hormone transport.

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What are hypophysiotropic hormones?

Hypothalamic hormones that regulate the anterior pituitary.

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What is prolactin?

Hormone that Stimulates milk secretion and production.

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What controls prolactin secretion?

Under inhibitory control by dopamine from the hypothalamus.

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What is lactogenesis?

Milk production triggered by prolactin to synthesize lactose, casein, and lipids.

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