Hypertension Treatment and RAAS Pathway Quiz
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Questions and Answers

Which drug class interacts with α or β receptors to treat hypertension?

  • Diuretics
  • Angiotensin-converting enzyme (ACE) inhibitors
  • Beta blockers (correct)
  • Calcium channel blockers
  • Which drug class can affect the renin-angiotensin-aldosterone system (RAAS)?

  • Diuretics
  • Calcium channel blockers
  • Beta blockers
  • Angiotensin-converting enzyme (ACE) inhibitors (correct)
  • Which drug class is used to treat hypertension by affecting the RAAS?

  • Beta blockers
  • Calcium channel blockers
  • Diuretics
  • Angiotensin-converting enzyme (ACE) inhibitors (correct)
  • Which drug class can cause the reabsorption of Na+ into the blood?

    <p>Angiotensin-converting enzyme (ACE) inhibitors</p> Signup and view all the answers

    Which drug class can affect the renin-angiotensin-aldosterone system (RAAS)?

    <p>Angiotensin-converting enzyme (ACE) inhibitors</p> Signup and view all the answers

    Which drug class can cause diuresis?

    <p>Diuretics</p> Signup and view all the answers

    Which drug class can cause diuresis?

    <p>Thiazide diuretics</p> Signup and view all the answers

    Why do some patients experience headaches and dizziness when taking nicorandil?

    <p>Because it dilates blood vessels and lowers blood pressure</p> Signup and view all the answers

    Which drug classes cause increases in the expression of hepatic LDL receptors?

    <p>Statins, fibrates, and bile acid sequestrants</p> Signup and view all the answers

    What is the mechanism of action of caspofungin?

    <p>Inhibition of fungal cell wall synthesis</p> Signup and view all the answers

    Which drug can reduce the effectiveness of the contraceptive pill even after a single dose?

    <p>RIF</p> Signup and view all the answers

    Which drug inhibits bacterial isoleucyl transferase to halt protein synthesis?

    <p>Mupirocin</p> Signup and view all the answers

    What is the mechanism of action of metronidazole?

    <p>Inhibition of DNA synthesis</p> Signup and view all the answers

    What is the target of the echinocandin drugs such as caspofungin?

    <p>Fungal cell membrane</p> Signup and view all the answers

    Study Notes

    Antihypertensive Drugs

    • Alpha or beta blockers interact with α or β receptors to treat hypertension.
    • ACE inhibitors, angiotensin receptor blockers (ARBs), and direct renin inhibitors can affect the renin-angiotensin-aldosterone system (RAAS) to treat hypertension.
    • Diuretics, such as thiazide diuretics, can cause the reabsorption of Na+ into the blood, leading to increased blood volume and hypertension.

    Adverse Effects of Nicorandil

    • Some patients experience headaches and dizziness when taking nicorandil due to its vasodilatory effects.

    Cholesterol-Lowering Drugs

    • Fibrates, resins, and statins can cause increases in the expression of hepatic LDL receptors, leading to increased cholesterol clearance.

    Antifungal Drugs

    • Caspofungin acts by inhibiting the synthesis of fungal cell walls, specifically by inhibiting the enzyme β-1,3-D-glucan synthase, which is necessary for fungal cell wall synthesis.
    • The target of the echinocandin drugs, such as caspofungin, is the fungal cell wall enzyme β-1,3-D-glucan synthase.

    Antibiotics

    • Rifampicin can reduce the effectiveness of the contraceptive pill even after a single dose.
    • Mupirocin inhibits bacterial isoleucyl transferase to halt protein synthesis, thereby treating bacterial infections.
    • Metronidazole acts by forming toxic metabolites that damage DNA, leading to bacterial death.

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    Description

    Test your knowledge on hypertension treatment and the renin-angiotensin-aldosterone system (RAAS) pathway with this quiz. Identify drug classes used to treat hypertension and their mechanisms of action, and learn about cardiovascular drugs that affect the RAAS pathway.

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