Hypersensitivity Reactions: Immunity and Disease Quiz
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Questions and Answers

What is the principal immunologic mechanism responsible for Type 1 hypersensitivity reactions?

  • IgE-mediated (correct)
  • Cellular effectors (T lymphocyte-mediated)
  • Antigen-Ab complexes
  • Ag-driven specific IgM or IgG
  • Which type of allergens typically trigger Type 1 hypersensitivity reactions?

  • Dust and mold spores
  • Chemicals and metals
  • Bacteria and viruses
  • Pollen, food, and drugs (correct)
  • What is the main effect of Type 1 hypersensitivity reactions on the body?

  • Decreased production of antigens
  • Rapid vascular leakage and mucosal secretions (correct)
  • Inhibition of immune response
  • Suppression of antibody production
  • Which type of hypersensitivity reaction is driven by cellular effectors?

    <p>Type 4</p> Signup and view all the answers

    What is the characteristic immunoglobulin involved in Type 1 hypersensitivity reactions?

    <p>IgE</p> Signup and view all the answers

    Which type of antigen triggers Type 3 hypersensitivity reactions?

    <p>Soluble antigen-antibody complexes</p> Signup and view all the answers

    What is the term used to describe individuals with a genetic and environmental propensity to develop Type I hypersensitivity reactions?

    <p>Atopic</p> Signup and view all the answers

    What is the approximate risk of an individual developing Type I hypersensitivity if both parents are atopic?

    <p>60%</p> Signup and view all the answers

    What is the primary role of allergen-specific IgE antibodies in immediate hypersensitivity reactions?

    <p>Release vasoactive amines and lipid mediators</p> Signup and view all the answers

    Which immune response is associated with Type I hypersensitivity?

    <p>Type 2</p> Signup and view all the answers

    What are the primary mediators involved in the late-phase reaction of immediate hypersensitivity?

    <p>Cytokines and chemokines</p> Signup and view all the answers

    What is the characteristic vascular response during immediate hypersensitivity reactions?

    <p>Wheal-and-flare reaction</p> Signup and view all the answers

    What type of allergens are most commonly associated with airborne allergies?

    <p>Dry particles carrying soluble proteins</p> Signup and view all the answers

    What characteristic favors type 2 immunity and IgE production in response to inhaled allergens?

    <p>Protease activity</p> Signup and view all the answers

    What do atopic individuals produce high levels of in response to certain substances?

    <p>IgE</p> Signup and view all the answers

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