Podcast
Questions and Answers
What is the principal immunologic mechanism responsible for Type 1 hypersensitivity reactions?
What is the principal immunologic mechanism responsible for Type 1 hypersensitivity reactions?
- IgE-mediated (correct)
- Cellular effectors (T lymphocyte-mediated)
- Antigen-Ab complexes
- Ag-driven specific IgM or IgG
Which type of allergens typically trigger Type 1 hypersensitivity reactions?
Which type of allergens typically trigger Type 1 hypersensitivity reactions?
- Dust and mold spores
- Chemicals and metals
- Bacteria and viruses
- Pollen, food, and drugs (correct)
What is the main effect of Type 1 hypersensitivity reactions on the body?
What is the main effect of Type 1 hypersensitivity reactions on the body?
- Decreased production of antigens
- Rapid vascular leakage and mucosal secretions (correct)
- Inhibition of immune response
- Suppression of antibody production
Which type of hypersensitivity reaction is driven by cellular effectors?
Which type of hypersensitivity reaction is driven by cellular effectors?
What is the characteristic immunoglobulin involved in Type 1 hypersensitivity reactions?
What is the characteristic immunoglobulin involved in Type 1 hypersensitivity reactions?
Which type of antigen triggers Type 3 hypersensitivity reactions?
Which type of antigen triggers Type 3 hypersensitivity reactions?
What is the term used to describe individuals with a genetic and environmental propensity to develop Type I hypersensitivity reactions?
What is the term used to describe individuals with a genetic and environmental propensity to develop Type I hypersensitivity reactions?
What is the approximate risk of an individual developing Type I hypersensitivity if both parents are atopic?
What is the approximate risk of an individual developing Type I hypersensitivity if both parents are atopic?
What is the primary role of allergen-specific IgE antibodies in immediate hypersensitivity reactions?
What is the primary role of allergen-specific IgE antibodies in immediate hypersensitivity reactions?
Which immune response is associated with Type I hypersensitivity?
Which immune response is associated with Type I hypersensitivity?
What are the primary mediators involved in the late-phase reaction of immediate hypersensitivity?
What are the primary mediators involved in the late-phase reaction of immediate hypersensitivity?
What is the characteristic vascular response during immediate hypersensitivity reactions?
What is the characteristic vascular response during immediate hypersensitivity reactions?
What type of allergens are most commonly associated with airborne allergies?
What type of allergens are most commonly associated with airborne allergies?
What characteristic favors type 2 immunity and IgE production in response to inhaled allergens?
What characteristic favors type 2 immunity and IgE production in response to inhaled allergens?
What do atopic individuals produce high levels of in response to certain substances?
What do atopic individuals produce high levels of in response to certain substances?