The Human Immune System
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Questions and Answers

Which cells are involved in the adaptive immune response?

  • B lymphocytes
  • Natural killer cells
  • Dendritic cells
  • T lymphocytes (correct)

    • What is the primary function of dendritic cells in the immune system?

  • To present antigens to T cells (correct)
  • To produce antibodies
  • To kill infected cells
  • To release inflammatory mediators

    • Which type of hypersensitivity reaction involves IgE antibodies and mast cell activation?

  • Type 3 hypersensitivity
  • Type 2 hypersensitivity
  • Type 1 hypersensitivity (correct)
  • Type 4 hypersensitivity

    • Which of the following is NOT a player of innate immunity?

    <p>Platelets (B)</p> Signup and view all the answers

    What is the function of the neutrophil granules?

    <p>To produce reactive oxygen species (C)</p> Signup and view all the answers

    What is the most common cause of infection in patients with Chronic Granulomatous Disease?

    <p>Staphylococcus aureus (A)</p> Signup and view all the answers

    What is the defect in innate immunity that causes Chronic Granulomatous Disease?

    <p>Defect in gp91phox component of NADPH oxidase (A)</p> Signup and view all the answers

    Which cells in our body present self-antigens on MHC-I?

    <p>Dendritic cells (B)</p> Signup and view all the answers

    Which cells express MHC-I?

    <p>All nucleated cells (C)</p> Signup and view all the answers

    Which cells usually present antigens from extracellular pathogens?

    <p>B-cells (A)</p> Signup and view all the answers

    Which cells recognize activating ligands universally expressed on nucleated cells?

    <p>Natural Killer (NK) cells (C)</p> Signup and view all the answers

    Which cells of innate immunity fight parasitic infection and contribute to allergic reactions?

    <p>Eosinophils (A)</p> Signup and view all the answers

    Which cells of innate immunity have additional capabilities for killing microbes, including acidification of phagosome and influx of reactive metals?

    <p>Macrophages (A)</p> Signup and view all the answers

    Which cells of innate immunity recognize peptidoglycan, lipoproteins, and bacterial LPS?

    <p>Macrophages (C)</p> Signup and view all the answers

    Which cells of adaptive immunity produce antibodies and develop in the bone marrow?

    <p>B cells (C)</p> Signup and view all the answers

    What are key signs and symptoms that indicate that someone is (or is likely) experiencing anaphylaxis?

    <p>Chest tightness and difficulty breathing (D)</p> Signup and view all the answers

    Why is it so important to recognize and treat anaphylaxis quickly?

    <p>To prevent long-term damage to organs (C)</p> Signup and view all the answers

    What type of hypersensitivity reaction does anaphylaxis fall under?

    <p>Type I (D)</p> Signup and view all the answers

    What are other common causes or triggers for anaphylaxis?

    <p>Latex allergy (C)</p> Signup and view all the answers

    Which of the following factors can lead to a failure of self-tolerance and the development of autoimmunity?

    <p>Genetic inheritance of susceptibility genes (B)</p> Signup and view all the answers

    What are the main factors involved in the current concepts of immunological tolerance?

    <p>Recognition of self and non-self antigens by antigen reactive T cells (D)</p> Signup and view all the answers

    Which type of immune reaction is associated with systemic lupus erythematosus (SLE)?

    <p>Type III - circulating immune complexes (A)</p> Signup and view all the answers

    Which type of hypersensitivity reaction is antibody independent and mediated by T cells?

    <p>Type IV - delayed-type hypersensitivity (C)</p> Signup and view all the answers

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