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What is the generic name for Hydralazine?
What is the generic name for Hydralazine?
- Hydralazine Sulfate
- Hydralazine Hydrochloride (correct)
- Hydralazine Acetate
- Hydralazine Phosphate
Which of the following are brand names for Hydralazine?
Which of the following are brand names for Hydralazine?
- Cardiovar
- Alazine (correct)
- Apresoline (correct)
- HydraTabs
What classifications does Hydralazine fall under?
What classifications does Hydralazine fall under?
Cardiovascular agent; nonnitrate vasodilator; antihypertensive
What is the pregnancy category of Hydralazine?
What is the pregnancy category of Hydralazine?
What are the available dosage forms of Hydralazine?
What are the available dosage forms of Hydralazine?
What is the dosage for adult patients with hypertension?
What is the dosage for adult patients with hypertension?
Which of the following are common side/adverse effects of Hydralazine?
Which of the following are common side/adverse effects of Hydralazine?
What are contraindications for the use of Hydralazine?
What are contraindications for the use of Hydralazine?
What nursing considerations should be taken when administering Hydralazine?
What nursing considerations should be taken when administering Hydralazine?
What client education is advised for patients taking Hydralazine?
What client education is advised for patients taking Hydralazine?
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Study Notes
Hydralazine Overview
- Generic name: Hydralazine Hydrochloride.
- Brand names include Alazine and Apresoline.
Drug Classification
- Classified as a cardiovascular agent and nonnitrate vasodilator.
- Functions as an antihypertensive medication.
Pregnancy Category
- Classified as Category C, indicating risk cannot be ruled out.
Dosage Forms
- Available in tablet forms of 10 mg, 25 mg, 50 mg, and 100 mg.
- Injectable form available at 20 mg/mL in vials.
Recommended Dosage
- For adult hypertension, oral doses range from 10-50 mg, taken four times daily.
- Injectable dosage of 10-20 mg every 4-6 hours.
- Geriatric patients should start with 10 mg, taken 2-3 times daily.
Side and Adverse Effects
- Common side effects include hypersensitivity reactions, headaches, dizziness, and gastrointestinal disturbances (nausea, vomiting).
- Cardiovascular side effects include palpitations and tachycardia.
- Possible serious effects: arrhythmia, shock, and SLE-like syndrome.
- Monitor for eosinophilia and liver-related issues, such as hepatitis and obstructive jaundice.
Contraindications
- Not recommended for patients with coronary artery disease, mitral valve rheumatic heart disease, and recent myocardial infarction.
- Contraindicated in individuals with tachycardia or systemic lupus erythematosus (SLE).
- Precautions advised for use in patients with a history of cerebrovascular accidents and advanced renal impairment.
Nursing Considerations
- Perform lab tests to check antinuclear antibody level before starting and periodically during treatment.
- Regularly monitor BUN, creatinine clearance, uric acid, potassium, and blood glucose levels.
- Closely observe blood pressure (BP) and heart rate (HR), especially during hypertensive crises.
- Monitor input and output in patients receiving parenteral administration or those with renal issues.
Client Education
- Advise patients to monitor weight and report any significant changes or edema to their physician.
- Educate that headaches and palpitations may occur shortly after the initial dose but typically resolve spontaneously.
- Recommend avoiding rapid position changes, prolonged standing, hot baths, strenuous exercise, and excessive alcohol consumption.
- Caution against driving or engaging in hazardous activities until individual response to the medication is understood.
- Discuss breastfeeding considerations with a physician prior to use.
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