Human Starvation and Survival Biology Quiz
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Questions and Answers

Which of the following is NOT a cause of muscle atrophy mentioned in the text?

  • High protein diet (correct)
  • Hormone excess or deficiency
  • Cachexia
  • Neuromuscular disease
  • What is the major source of urinary nitrogen mentioned in the text?

  • Carbohydrates metabolism
  • Vitamins breakdown
  • Fats metabolism
  • Amino acids from protein breakdown (correct)
  • What is the term used for the age-related loss of muscle mass mentioned in the text?

  • Anorexia
  • Cachexia
  • Sarcopenia (correct)
  • Myasthenia
  • What is the physiological condition created in the body as a consequence of chronic insufficient food intake?

    <p>Starvation</p> Signup and view all the answers

    What are the two types of starvation mentioned in the text?

    <p>Physiological and pathological</p> Signup and view all the answers

    What is the main ethical consideration mentioned in nutrition research regarding malnutrition?

    <p>To do no harm and treat malnutrition</p> Signup and view all the answers

    What is a characteristic of malnutrition mentioned in the text?

    <p>It often involves deficiencies in multiple macronutrients</p> Signup and view all the answers

    What are the side effects and symptoms of zinc deficiency mentioned in the text?

    <p>Similar to protein deficiency</p> Signup and view all the answers

    What was the outcome of the study where men were fed a low protein and energy diet for 6 months?

    <p>They felt terrible psychologically and physically</p> Signup and view all the answers

    What is the conclusion about people surviving starvation mentioned in the text?

    <p>They often struggle to regain normal health</p> Signup and view all the answers

    What is the primary focus of clinical nutrition mentioned in the text?

    <p>Protein-energy malnutrition</p> Signup and view all the answers

    What was the percentage of total weight loss experienced by conscientious objectors subjected to 1500 kcal/day and 50g protein/day for 6 months?

    <p>23%</p> Signup and view all the answers

    Which cellular regulators contribute to successful adaptation at the cellular level in starvation?

    <p>Gcn2 and AMPK</p> Signup and view all the answers

    What are the clinical features associated with Protein-energy malnutrition (PEM)?

    <p>Fatigue, immunodeficiency, and reduced tolerance to stress</p> Signup and view all the answers

    What were the lasting effects on infants' health due to the 'Hunger winter' in the Netherlands and the 1998 Ice Storm in Montreal?

    <p>Increased risk of chronic diseases and small gestational age</p> Signup and view all the answers

    What is the crucial period for a child's nutrition and development, according to the text?

    <p>The first 1000 days from conception to the second birthday</p> Signup and view all the answers

    What are the clinical manifestations of edematous undernutrition?

    <p>Fluid accumulation and failed adaptation</p> Signup and view all the answers

    Which infections are common in undernourished individuals, impacting immunity and overall health?

    <p>Diarrhea, pneumonia, and tuberculosis</p> Signup and view all the answers

    What does medical nutrition therapy for rehabilitation involve?

    <p>Cautious intervention, treating infections, and long-term prevention programs to increase food security</p> Signup and view all the answers

    What can exacerbate unsuccessful adaptation in undernutrition?

    <p>Micronutrient deficiencies and stressors like trauma, cancer, or inflammation</p> Signup and view all the answers

    What responses occur in different infection scenarios, impacting the body's metabolic state?

    <p>Hypermetabolic and hypometabolic responses</p> Signup and view all the answers

    What are the six causes of muscle atrophy mentioned in the text?

    <ol> <li>Cachexia – cancer, systemic inflammation cortisol, epinephrine</li> <li>Hormone excess or deficiency like decrease in insulin, insulin growth factor</li> <li>Old age – sarcopenia</li> <li>Protein-energy malnutrition – starvation</li> <li>Inactivity – disuse atrophy bed rest, space flight, 0 gravity</li> <li>Neuromuscular disease.</li> </ol> Signup and view all the answers

    What is the importance of intervening before muscle atrophy becomes too intense, according to the text?

    <p>The importance of intervening before muscle atrophy becomes too intense is to prevent the loss of lean mass and potentially compromising functions.</p> Signup and view all the answers

    What is the significance of urinary nitrogen in the context of muscle atrophy and malnutrition?

    <p>A major increase in urinary nitrogen signifies a negative nitrogen balance, indicating the loss of lean mass and potential compromise of bodily functions due to protein breakdown.</p> Signup and view all the answers

    What are the potential consequences of not addressing the metabolic response to injury and illness promptly?

    <p>The potential consequences of not addressing the metabolic response to injury and illness promptly include the development of sarcopenia and the risk of muscle atrophy due to various factors such as cachexia, hormonal imbalances, old age, malnutrition, inactivity, and neuromuscular diseases.</p> Signup and view all the answers

    Explain the difference between physiological and pathological starvation mentioned in the text.

    <p>Physiological starvation is adaptive to promote survival, while pathological starvation involves some sort of stress that compromises adaptation, such as infection, cancer, drugs, or surgery.</p> Signup and view all the answers

    What are the challenges and ethical considerations in conducting nutrition research on malnutrition?

    <p>The challenges include the inability to put healthy humans on a diet to induce malnutrition, as it goes against the principle of 'do no harm.' Ethical considerations dictate that individuals with malnutrition must be treated rather than observed, and standard care should be offered as a control group in research studies.</p> Signup and view all the answers

    Describe the complexity of malnutrition as mentioned in the text.

    <p>Malnutrition is a complex energy deficiency along with protein, and it rarely involves a single nutrient deficiency. It often includes deficiencies in other macronutrients, making it a multifaceted condition.</p> Signup and view all the answers

    What are the challenges in assessing zinc status in individuals with malnutrition?

    <p>Zinc deficiency can cause side effects and symptoms similar to protein deficiency, making it challenging to diagnose subclinical infections. Additionally, plasma zinc levels may not accurately reflect zinc status.</p> Signup and view all the answers

    Discuss the psychological and physical impact of a low-protein and low-energy diet based on the study mentioned in the text.

    <p>Individuals fed a low-protein and low-energy diet for six months experienced severe psychological and physical distress, making it difficult for them to recover from the diet.</p> Signup and view all the answers

    Explain the impact of the Dutch Famine (1944-45) on infants' health and development, as mentioned in the text.

    <p>The Dutch Famine resulted in epigenetic changes, with infants facing chronic disease risks and small gestational age.</p> Signup and view all the answers

    What are the clinical manifestations of edematous undernutrition mentioned in the text?

    <p>Edematous undernutrition leads to fluid accumulation and is associated with failed adaptation and subclinical infections.</p> Signup and view all the answers

    What are the cellular regulators involved in successful adaptation at the cellular level in starvation?

    <p>Cellular regulation in starvation involves Gcn2 and AMPK, contributing to successful adaptation at the cellular level.</p> Signup and view all the answers

    What infections are common in undernourished individuals, impacting immunity and overall health?

    <p>Infections such as diarrhea, pneumonia, and tuberculosis are common in undernourished individuals, impacting immunity and overall health.</p> Signup and view all the answers

    What is the impact of protein-energy malnutrition (PEM) on individuals, as mentioned in the text?

    <p>Protein-energy malnutrition (PEM) leads to clinical features such as fatigue, immunodeficiency, and reduced tolerance to stress.</p> Signup and view all the answers

    Describe the physiological condition created in the body as a consequence of chronic insufficient food intake.

    <p>Chronic insufficient food intake leads to starvation, resulting in the body's energy expenditure and protein requirement reducing to survive long-term undernutrition.</p> Signup and view all the answers

    What is the primary focus of medical nutrition therapy for rehabilitation, as mentioned in the text?

    <p>Medical nutrition therapy for rehabilitation involves cautious intervention, treating infections, and long-term prevention programs to increase food security.</p> Signup and view all the answers

    Study Notes

    The Biology of Human Starvation and Survival

    • Conscientious objectors were subjected to 1500 kcal/day and 50g protein/day for 6 months, resulting in a 23% total weight loss and significant lean tissue and fat mass reduction.
    • Adapting to starvation, the body's energy expenditure and protein requirement reduced to survive long-term undernutrition.
    • Cellular regulation in starvation involves Gcn2 and AMPK, contributing to successful adaptation at the cellular level.
    • Protein-energy malnutrition (PEM) leads to clinical features such as fatigue, immunodeficiency, and reduced tolerance to stress.
    • The Dutch Famine (1944-45) resulted in epigenetic changes, with infants facing chronic disease risks and small gestational age.
    • The "Hunger winter" in the Netherlands and the 1998 Ice Storm in Montreal had lasting effects on infants' health due to malnutrition.
    • The first 1000 days from conception to the second birthday are crucial for a child's nutrition and development.
    • Edematous undernutrition leads to fluid accumulation and is associated with failed adaptation and subclinical infections.
    • Infections such as diarrhea, pneumonia, and tuberculosis are common in undernourished individuals, impacting immunity and overall health.
    • Medical nutrition therapy for rehabilitation involves cautious intervention, treating infections, and long-term prevention programs to increase food security.
    • Unsuccessful adaptation in undernutrition can be exacerbated by micronutrient deficiencies and stressors like trauma, cancer, or inflammation.
    • Hypermetabolic and hypometabolic responses occur in different infection scenarios, impacting the body's metabolic state.

    The Biology of Human Starvation and Survival

    • Conscientious objectors were subjected to 1500 kcal/day and 50g protein/day for 6 months, resulting in a 23% total weight loss and significant lean tissue and fat mass reduction.
    • Adapting to starvation, the body's energy expenditure and protein requirement reduced to survive long-term undernutrition.
    • Cellular regulation in starvation involves Gcn2 and AMPK, contributing to successful adaptation at the cellular level.
    • Protein-energy malnutrition (PEM) leads to clinical features such as fatigue, immunodeficiency, and reduced tolerance to stress.
    • The Dutch Famine (1944-45) resulted in epigenetic changes, with infants facing chronic disease risks and small gestational age.
    • The "Hunger winter" in the Netherlands and the 1998 Ice Storm in Montreal had lasting effects on infants' health due to malnutrition.
    • The first 1000 days from conception to the second birthday are crucial for a child's nutrition and development.
    • Edematous undernutrition leads to fluid accumulation and is associated with failed adaptation and subclinical infections.
    • Infections such as diarrhea, pneumonia, and tuberculosis are common in undernourished individuals, impacting immunity and overall health.
    • Medical nutrition therapy for rehabilitation involves cautious intervention, treating infections, and long-term prevention programs to increase food security.
    • Unsuccessful adaptation in undernutrition can be exacerbated by micronutrient deficiencies and stressors like trauma, cancer, or inflammation.
    • Hypermetabolic and hypometabolic responses occur in different infection scenarios, impacting the body's metabolic state.

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    Description

    Test your knowledge on the biology of human starvation and survival with this quiz. Explore the effects of undernutrition, adaptation to starvation, cellular regulation, and the impact of malnutrition on health and development. Learn about historical famines, epigenetic changes, and medical nutrition therapy for rehabilitation.

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