Energy Production during Starvation
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Questions and Answers

how does the body produce energy during starvation

nutrients stored in the body are oxidised for the production of energy

during a fed state how are nutrients stored?

in the form of glycogen in the liver and lipids in the adipose tissue

how are glycogen reserves used during starvation?

glycogen reserves in the liver will be used first. glycogen will be broken done into glucose which will go through glycolysis to produce ATP

what is glycolysis and describe the process

<p>one molecule of glucose is converted into two molecules of pyruvate with the net gain of 2 ATP molecules and 2 NADH molecules. this occurs in the cytosol. pyruvate then enters the mitochondria converts into acetyl-coa which enters the krebs cycle to produce ATP</p> Signup and view all the answers

what is glycogenolysis and describe the process

<p>the breakdown of glycogen to glucose. glycogen is broken down into glucose-1-phosphate and then converted into glucose in the liver.</p> Signup and view all the answers

describe the process of lipolysis in starvation

<p>hormone-sensitive lipase in adipose tissue is activated in response to low insulin and high levels of hormones such as glucagon, adrenaline and cortisol. hormone-sensitve lipase breaks down triglycerides into free fatty acids and glycerol</p> Signup and view all the answers

what is gluconeogenesis and what are the 3 main substrates used?

<p>the production of glucose from non carbohydrate sources. 2 pyruvate molecules are converted into glucose. uses glycerol from fatty acid breakdown, pyruvate/lactate from the end of glycolysis and oxaloacetate from the citric acid cycle from acetyl-CoA.</p> Signup and view all the answers

what is the result of using lipid reserves

<p>release of glycerol which feeds gluconeogenesis and fatty acid release which are converted into acetyl-CoA which through the krebs cycle is converted into glucose</p> Signup and view all the answers

how does gluconeogenesis produce glucose?

<p>pyruvate is carboxylated into oxaloacetate, which is converted into malate so it can enter the cytosol, then its converted back into oxaloacetate. this then through a series of reactions, produces glucose</p> Signup and view all the answers

what is beta-oxidation?

<p>the process in which free fatty acids are converted into acetyl-CoA.</p> Signup and view all the answers

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