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Skin Histology (T&F)
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Skin Histology (T&F)

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Questions and Answers

Meissner's corpuscles are sensory receptors that detect pain.

False

Pacini corpuscles are responsible for detecting vibrations.

True

The hypodermis is also known as the superficial fascia.

True

The dermis is the outermost layer of the skin.

<p>False</p> Signup and view all the answers

Langerhans cells are found in the dermis.

<p>False</p> Signup and view all the answers

Sebaceous glands are responsible for producing sweat.

<p>False</p> Signup and view all the answers

The anagen phase of hair growth is the resting phase.

<p>False</p> Signup and view all the answers

The telogen phase of hair growth is the phase of apoptosis.

<p>False</p> Signup and view all the answers

Apocrine sweat glands are found only in the axillary and perineal regions.

<p>True</p> Signup and view all the answers

The hair follicle resting phase is known as anagen.

<p>False</p> Signup and view all the answers

The external epithelial hair root sheath is composed of stratified squamous epithelium.

<p>True</p> Signup and view all the answers

Myoepithelial cells are a type of epithelial cell.

<p>False</p> Signup and view all the answers

The pilo-sebaceous unit is composed of a hair follicle and a sweat gland.

<p>False</p> Signup and view all the answers

The hair cuticle is the outermost layer of the hair shaft.

<p>True</p> Signup and view all the answers

Mammary glands have a simple cuboidal epithelium.

<p>True</p> Signup and view all the answers

Ceruminous glands produce milk.

<p>False</p> Signup and view all the answers

Eccrine sweat glands have a large lumen.

<p>False</p> Signup and view all the answers

Apocrine sweat glands release their products in a merocrine way.

<p>True</p> Signup and view all the answers

The stratum germinatum is a layer of the epidermis.

<p>False</p> Signup and view all the answers

The hair base is surrounded by a basement membrane.

<p>True</p> Signup and view all the answers

The pattern of ridges and grooves on the human skin is identical for identical twins.

<p>False</p> Signup and view all the answers

The stratum basale is the uppermost layer of the epidermis.

<p>False</p> Signup and view all the answers

Keratohyaline granules are found in the stratum lucidum.

<p>False</p> Signup and view all the answers

The papillary layer is a layer of the epidermis.

<p>False</p> Signup and view all the answers

Melanocytes are found in the stratum corneum.

<p>False</p> Signup and view all the answers

Tyrosinase is synthesized in the Golgi apparatus.

<p>False</p> Signup and view all the answers

Melanin synthesis begins in the ellipsoid stage III melanosomes.

<p>False</p> Signup and view all the answers

A mature melanin granule has lost tyrosinase and other activities and has the internal matrix completely filled with melanin.

<p>True</p> Signup and view all the answers

The mature granules are spherical in shape and approximately 0.5 by 1 μm in size.

<p>False</p> Signup and view all the answers

Tonofibrils are found in the stratum corneum.

<p>False</p> Signup and view all the answers

Study Notes

Dermatoglyphics (Fingerprints)

  • Certain areas of the human skin show ridges and grooves, arranged in distinctive patterns, which are unique for each individual (even differing in identical twins)

Skin Layers

  • The epidermis consists of:
    • Stratum corneum
    • Stratum lucidum
    • Stratum granulosum
    • Stratum spinosum
    • Stratum basale
  • The dermis consists of:
    • Papillary layer
    • Reticular layer

Epidermal Cells

  • Produce keratin, the major structural protein of the epidermis
  • Melanocytes:
    • Derived from neural crest
    • Round cells with cytoplasmic (dendritic) projections scattered among the basal cells of the stratum basale
    • Synthesize tyrosinase in rough ER, processed through the Golgi apparatus, and accumulate in vesicles (stage I melanosomes)
    • Melanin synthesis begins in ovoid stage II melanosomes, and accumulates in stage III
    • Mature melanin granules (stage IV) have lost tyrosinase and other activities and have an internal matrix completely filled with melanin
  • Langerhans cells:
    • Bind, process, and present antigens to T lymphocytes, mediating immune response

Skin Types

  • Thick skin (e.g. palms, soles)
  • Thin skin (e.g. limbs, torso)

Dermal Papillae

  • Formed by collagen (type I) and elastic fibers regularly oriented, forming lines of tension in the skin (Langer's lines)

Skin Receptors

  • Pacinian corpuscles
  • Meissner's corpuscles
  • Merkel cells
  • Ruffini's corpuscules

Hypodermis

  • Also called "superficial fascia"
  • Fatty tissue which stores fat and anchors skin (areolar tissue and adipose cells)
  • Different patterns of accumulation (male/female)

Hair

  • Pilosebaceous unit
  • Hair follicles and hairs
  • Phases of hair development:
    • Anagen (active phase)
    • Catagen (apoptosis-driven involution)
    • Telogen (resting phase)

Sebaceous Glands

  • Associated with hair follicles
  • Produce sebum, an oily substance that lubricates hair and skin

Sweat Glands

  • Types:
    • Eccrine (merocrine)
    • Apocrine
    • Modified apocrine (e.g. ceruminous, mammary)
  • Eccrine glands:
    • Most numerous
    • True sweat: 99% water, some salts, traces of waste
    • Open through pores
  • Apocrine glands:
    • Confined to axillary, anal, and genital areas
    • Ducts open into hair follicles
    • Organic molecules in it decompose with time, causing odor

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Related Documents

skin lecture.pdf

Description

Test your knowledge of the human skin, including dermatoglyphics, skin layers, and epidermal cells. Learn about the unique features of fingerprints and the different layers of the epidermis and dermis.

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