Human Physiology Lecture: Endochondral Ossification and Skeletal System

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17 Questions

Which hormone is responsible for lowering blood Ca levels by inhibiting osteoclast activity?

Calcitonin

What type of fracture involves an exposed bone and intact skin?

Open

During the inflammatory stage of bone healing, what is formed at the fracture site?

Hematoma

Which type of fracture is characterized by a twisting injury?

Spiral

What is the critical physiological regulator of many processes including muscle contraction?

Calcium

Which stage of bone healing involves the formation of a callus and new blood vessels?

Reparative stage

What is the function of osteoclasts in bone physiology?

Reabsorption of bone

Which cells are responsible for depositing new bone material during bone remodeling?

Osteoblasts

What is the process that involves the formation of bone within mesenchyme?

Intramembranous ossification

What hormone is secreted from C cells in the thyroid gland for calcium ion regulation?

Calcitonin

What is the main function of calcitonin in bone physiology?

Inhibiting bone breakdown

Which cells are responsible for converting woven bone into lamellar bone during bone remodeling?

Osteoblasts

What is the key signal for the secretion of PTH?

Reduction of blood Ca levels

How does Calcitriol assist PTH in the kidney tubules?

By preventing Ca removal through urine

What is the main function of PTH in relation to bone reabsorption?

Increase osteoclast activity

Which organ is primarily responsible for Calcitriol activation?

Kidney

What happens to cartilaginous tissue to maintain blood Ca levels within homeostatic limits?

It becomes ossified and rebuilt

Explore the process of endochondral ossification where bone gradually replaces a cartilage model. Learn about the anatomy, physiology, and pathophysiology of the skeletal system including the roles of osteoblasts, osteocytes, and osteoclasts.

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