Human Physiology: Body Fluids and Composition

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Questions and Answers

What percentage of body weight in male adults is made up of body fluids?

  • 70%
  • 60% (correct)
  • 45%
  • 50%

Which group of individuals tends to have a higher percentage of body fluid?

  • Obese individuals
  • Infants (correct)
  • Adult women
  • Older adults

What is the primary location of intracellular fluids (ICF) in the body?

  • Skin tissue
  • Fat cells
  • Blood plasma
  • Skeletal muscle mass (correct)

Which of the following factors does NOT affect total body water?

<p>Dietary habits (B)</p> Signup and view all the answers

What percentage of body weight do older adults typically consist of in terms of body fluids?

<p>45-55% (D)</p> Signup and view all the answers

Which body component has the highest water content?

<p>Muscle (B)</p> Signup and view all the answers

What is one of the main functions of extracellular fluid (ECF)?

<p>Maintaining blood volume (A)</p> Signup and view all the answers

What is one of the primary effects of catecholamines on potassium levels?

<p>Increases potassium excretion (C)</p> Signup and view all the answers

Which diagnostic test is most indicative of dehydration?

<p>Specific gravity (D)</p> Signup and view all the answers

Which statement about body fluid composition is correct?

<p>Infants have a higher percentage of body fluid than older adults. (D)</p> Signup and view all the answers

What is a common cause of hypokalemia?

<p>Kidney dysfunction (C)</p> Signup and view all the answers

What role does aldosterone play in potassium regulation?

<p>Promotes potassium excretion (D)</p> Signup and view all the answers

Which condition is associated with hypocalcemia?

<p>Diabetic ketoacidosis (B)</p> Signup and view all the answers

What activates the protein channel that allows glucose to enter the cell?

<p>Insulin (D)</p> Signup and view all the answers

Which process describes the movement of solutes from an area of high concentration to an area of low concentration?

<p>Diffusion (A)</p> Signup and view all the answers

Which of the following statements about the sodium-potassium pump is true?

<p>It moves Na+ out of and K+ into the cell requiring ATP. (B)</p> Signup and view all the answers

What happens to a cell in a hypotonic solution?

<p>The cell swells. (B)</p> Signup and view all the answers

During the process of osmosis, which substance is typically moving?

<p>Water (B)</p> Signup and view all the answers

In the described oxidation reaction, how many molecules of water are produced?

<p>16 (A)</p> Signup and view all the answers

What occurs at the neuromuscular junction when acetylcholine is released?

<p>Muscles contract. (C)</p> Signup and view all the answers

Which type of transport mechanism requires energy in the form of ATP?

<p>Active transport (C)</p> Signup and view all the answers

Which of the following is an effect of Atrial Natriuretic Hormone?

<p>Reduces sodium retention (C)</p> Signup and view all the answers

What electrolyte primarily exists as a cation in intracellular fluid?

<p>Potassium (K+) (C)</p> Signup and view all the answers

Which diagnostic test would indicate a fluid volume deficit?

<p>Increased plasma concentration (B)</p> Signup and view all the answers

What is a common symptom associated with fluid volume deficit?

<p>Dry mouth (A)</p> Signup and view all the answers

Which condition is characterized by elevated osmolality?

<p>Fluid volume deficit (D)</p> Signup and view all the answers

Which electrolyte imbalance is likely in a patient with ineffective tissue perfusion due to fluid loss?

<p>Hyponatremia (C)</p> Signup and view all the answers

What is the role of electrolytes in the body?

<p>Maintain body fluid volume and osmolality (D)</p> Signup and view all the answers

Which of the following symptoms is NOT typically associated with fluid volume deficit?

<p>Sudden weight gain (B)</p> Signup and view all the answers

What is a primary nursing diagnosis when dealing with fluid overload?

<p>Fluid Volume Excess r/t fluid overload (D)</p> Signup and view all the answers

Which collaborative management strategy is essential for a patient with fluid overload?

<p>Strict Fluid Restriction (C)</p> Signup and view all the answers

Which diagnostic test is likely to indicate fluid overload if increased BUN and creatinine levels are observed?

<p>CVP measurements (B)</p> Signup and view all the answers

In the context of administering fluids, what does PLR refer to?

<p>Progressive Liquid Replacement (A)</p> Signup and view all the answers

What is a consequence of excessive administration of hypotonic solutions?

<p>Fluid overload and peripheral edema (D)</p> Signup and view all the answers

Which nursing intervention should be prioritized for a patient showing signs of activity intolerance?

<p>Implement safety measures such as side rails (D)</p> Signup and view all the answers

What can cause an increase in production of ADH, leading to fluid retention?

<p>Renal failure (A)</p> Signup and view all the answers

Which factor is least associated with fluid volume excess?

<p>Dehydration (D)</p> Signup and view all the answers

What happens to red blood cells in a hypotonic solution?

<p>They swell due to fluid absorption. (A)</p> Signup and view all the answers

What is the primary characteristic of an isotonic solution?

<p>Equal solute concentration to blood plasma. (C)</p> Signup and view all the answers

What is the definition of osmolality?

<p>Concentration of particles per kilogram of solution. (A)</p> Signup and view all the answers

Hydrostatic pressure is best described as which of the following?

<p>The pushing force from blood on vessel walls. (D)</p> Signup and view all the answers

Which solution would be classified as hypotonic?

<p>0.45 NaCl (D)</p> Signup and view all the answers

Oncotic pressure primarily helps in which of the following?

<p>Pulling fluids inward into the capillaries. (C)</p> Signup and view all the answers

What is the typical range for serum osmolality?

<p>270 – 300 mOsm/kg (C)</p> Signup and view all the answers

What effect does a hypertonic solution have on red blood cells?

<p>They shrink due to fluid loss. (B)</p> Signup and view all the answers

Flashcards

Intracellular Fluid (ICF)

Fluid inside cells, making up around 70% of total body water. It plays a crucial role in cell function and maintaining the internal environment.

Extracellular Fluid (ECF)

Fluid outside cells, making up the remaining 30% of total body water. It includes blood plasma and interstitial fluid.

Body Weight and Fluids

A person's overall weight is influenced by the amount of fluid they carry. This is because body fluids contribute a significant portion of our overall weight.

Age and Body Fluid Percentage

The percentage of body fluid is higher in younger people than in older adults.

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Gender and Body Fluid Percentage

Men have more body fluid than women because of differences in body composition, such as muscle mass.

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Obesity and Body Fluid Percentage

Fat cells contain less water compared to lean muscle mass, so obese individuals tend to have lower overall body fluid percentages.

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Skeleton and Body Fluid

The skeleton is made up of bones and contains a lower percentage of water compared to other tissues like skin or muscle.

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Water Content in Tissues

Blood, skin, and muscle tissue are known to have the highest water content in the body.

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Simple Diffusion

Movement of a substance across a membrane from an area of higher concentration to an area of lower concentration.

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Simple Osmosis

Movement of water across a semi-permeable membrane from an area of high water concentration to an area of low water concentration.

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Active Transport

The movement of substances across a cell membrane against their concentration gradient (from low to high). Requires energy (ATP).

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Sodium-Potassium Pump

A specific type of active transport that pumps sodium ions (Na+) out of the cell and potassium ions (K+) into the cell. Important for maintaining cell potential and nerve impulse conduction.

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Insulin-Dependent Glucose Transport

A protein channel that opens in the cell membrane to allow glucose to enter the cell. Insulin is required for this to happen.

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Hypotonic Solution

A solution that has a lower concentration of solutes compared to the cell. When a cell is placed in a hypotonic solution, water moves into the cell, causing it to swell.

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Hypertonic Solution

A solution that has a higher concentration of solutes compared to the cell. When a cell is placed in a hypertonic solution, water moves out of the cell, causing it to shrink.

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Isotonic Solution

A solution that has the same concentration of solutes as the cell. When a cell is placed in an isotonic solution, there is no net movement of water.

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Hydrostatic Pressure

The force exerted by blood pushing against the walls of blood vessels.

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Oncotic Pressure (Colloid Osmotic Pressure)

The pressure required to oppose the osmotic pull of proteins, mainly albumin, drawing fluid into the blood vessels.

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Tonicity

The ability of a solution to change the volume of a cell due to water movement across the cell membrane.

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Osmolarity

The concentration of dissolved particles (solutes) per liter of solution.

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Osmolality

The concentration of dissolved particles (solutes) per kilogram of solution.

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Extracellular fluid

Fluid in the space between cells, encompassing blood plasma and interstitial fluid.

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Intracellular fluid

Fluid inside cells, vital for cell function and maintaining internal balance.

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Edema

An excessive accumulation of fluid in interstitial spaces or the extracellular compartment causing swelling.

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Fluid Volume Excess

A condition characterized by an abnormal increase in body fluid volume.

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Fluid Volume Deficit

A condition where a person's body cannot retain adequate fluids, leading to dehydration.

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Fluid Replacement

A medical intervention aimed at replacing lost fluids, often through oral rehydration or intravenous solutions.

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Hypokalemia

A common electrolyte imbalance characterized by low potassium levels in the blood (<3.5 mEq/L).

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Hyperkalemia

A condition characterized by high potassium levels in the blood (>5.5 mEq/L). It can be caused by various factors, including kidney dysfunction, excess intake, and certain medications.

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Aldosterone

A hormone released by the adrenal glands that helps regulate blood pressure and electrolyte balance. It enhances sodium reabsorption, contributing to fluid retention and potassium excretion.

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Sodium (Na+)

Sodium (Na+) is a crucial electrolyte found primarily in the extracellular fluid. It plays a vital role in maintaining fluid balance, nerve impulse conduction, and muscle contraction.

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Potassium (K+)

Important electrolyte that helps regulate heart rhythm, nerve function, and muscle contraction. Low potassium levels (hypokalemia) can lead to heart problems, fatigue, muscle cramps, and weakness.

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What is Atrial Natriuretic Hormone (ANH)?

A hormone released by the heart's atria (upper chambers) in response to high blood pressure or excess blood volume. It helps lower blood pressure and regulate fluid balance by promoting sodium and water excretion, reducing thirst, and dilating blood vessels.

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What are Baroreceptors?

Specialized sensory receptors located in blood vessel walls that detect changes in blood pressure. They send signals to the brain, initiating adjustments to maintain blood pressure within a normal range.

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What are Osmoreceptors?

Specialized sensors located in the brain that detect changes in the concentration of solutes (like salt) in the blood. They help regulate fluid balance by triggering thirst and influencing hormone release to control water reabsorption.

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What are Electrolytes?

Substances that dissolve in solution and are capable of conducting an electrical current due to their ability to break into charged particles (ions). Electrolytes play vital roles in maintaining fluid balance, nerve function, and muscle contraction.

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What are Cations?

Positively charged ions.

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What are Anions?

Negatively charged ions.

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What is Hypertonic/Hyperosmolar Fluid Volume Deficit (FVD)?

A fluid volume deficit where both the volume (amount) and concentration (osmolality) of body fluids are decreased. This indicates a loss of both water and electrolytes.

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What is Isotonic/Iso-osmolar Fluid Volume Deficit (FVD)?

A fluid volume deficit where the volume of body fluids is decreased, but the concentration remains normal. This indicates a loss of water, but electrolytes are relatively balanced.

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Study Notes

Nursing Care of At-Risk and Sick Adult Clients

  • Focuses on alterations/problems with fluid and electrolyte balance.

Body Fluids and Electrolytes

  • Approximately 60% of an adult's weight is fluid.
  • Men have a higher percentage of body fluid than older people.
  • Obese individuals have more body fluid than correspondingly sized women and have less than those who are thin. Body fluid is less in skeletal than muscle, skin, and blood.
  • Body fluids are divided into intracellular (ICF) and extracellular (ECF) compartments.
  • ICF comprises 70% of body fluid.
  • ECF comprises 30% of body fluid and includes interstitial fluid (ISF) and intravascular fluid (IVF).
  • Transcellular fluid is the smallest division within ECF. examples are cerebrospinal fluid, serous fluids, synovial fluids, humors of the eyeball, and digestive juices.

Body Water Distribution

  • Infants have 80% body weight as water.
  • Adult males have 60% body weight as water.
  • Adult females have 50% body weight as water.
  • Older adults have 45-55% body weight as water.

Fluid Functions

  • Extracellular fluid (ECF) maintains blood volume and transports substances to and from cells.
  • Intracellular fluid (ICF) provides an aqueous medium for cellular chemical functions.
  • Maintains body temperature through processes like perspiration.
  • Eliminates waste products.

Fluid Output

  • Sensible fluid loss (e.g., urine).
  • Insensible fluid loss (e.g., sweat, respiration).

Organs for Fluid Loss

  • Kidneys: Produce urine (1-2 liters in adults).
  • Skin: Facilitates insensible fluid loss (sweat, approximately 600ml/day).

Fluid Transport Mechanisms

  • Passive transport includes diffusion (movement of solutes from higher to lower concentration) and osmosis (movement of solvent from lower to higher solute concentration).
  • Active transport mechanisms (e.g., sodium-potassium pump) require energy to move substances against their concentration gradient.

Hydrostatic Pressure

  • The force exerted by the blood against the vessel walls.

Oncotic Pressure

  • The osmotic pressure exerted by proteins in the blood, pulling fluid back into the capillaries.

Fluid Concentration

  • Osmolarity: The concentration of solute per liter of solution.
  • Osmolality: The concentration of solute per kilogram of water.

Tonicity

  • Isotonic solutions have the same solute concentration as blood plasma.
  • Hypotonic solutions have a lower solute concentration than blood plasma.
  • Hypertonic solutions have a higher solute concentration than blood plasma.

Fluid Imbalances

  • Fluid volume deficit (FVD)
  • Fluid volume excess (FVE)

Electrolytes

  • Cations: Positively charged ions (sodium, potassium, calcium, magnesium)
  • Anions: Negatively charged ions (chloride, phosphate)
  • Key electrolytes affect osmolality, maintaining fluid balance, nerve impulse conduction and muscle contraction. Important for metabolic and chemical reactions.

Electrolyte Imbalances

  • Hyponatremia, Hypokalemia, Hypocalcemia, Hypomagnesemia
  • Hypernatremia, Hyperkalemia, Hypercalcemia, Hypermagnesemia

Management Strategies

  • Fluid replacement, monitoring, and safety precautions.

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