Human Pathology: Bone Disorders and Tumours Quiz

Metastatic tumours are more common than primary bone tumours. (True/False)

Clinical effects of bone metastases include pain, bone destruction, and vertebral collapse. (True/False)

Skeletal metastases in adults originate from cancers of the thyroid, prostate, breast, kidney, and lung. (True/False)

Children's metastatic disease commonly derives from neuroblastoma, Wilms tumour, Ewing sarcoma, and rhabdomyosarcoma. (True/False)

Osteosarcoma is one of the commonest malignant tumours of bone with a good prognosis. (True/False)

Osteosarcoma usually occurs between 10-25 years of age. (True/False)

Chondrosarcoma is the most common malignant bone tumor.

Ewing's sarcoma usually arises in the epiphysis of long bones.

Osteosarcomas can exhibit osteoblastic, chondroblastic, or fibroblastic differentiation.

Gouty arthritis is an example of chronic arthritis.

Rheumatoid arthritis is an example of acute arthritis.

Paget's disease of bone is a predisposing factor for osteosarcomas.

Chromosomal translocation between chromosome 11 & 22 is a predisposing factor for Ewing's sarcoma.

Arthritis refers to the inflammation of one joint only.

Fibrous dysplasia is a predisposing factor for chondrosarcoma.

Ewing's sarcoma has a poor prognosis.

Metastatic tumours are more common than primary bone tumours. (True/False)

Chondrosarcoma is the most common malignant bone tumor. (True/False)

Osteosarcoma is one of the commonest malignant tumors of bone with a good prognosis. (True/False)

Ewing's sarcoma usually arises in the epiphysis of long bones. (True/False)

Arthritis refers to the inflammation of one joint only. (True/False)

Paget's disease of bone is a predisposing factor for osteosarcomas. (True/False)

Ewing's sarcoma most probably originates from endothelial or neurogenic cells in the bone marrow.

Rheumatoid arthritis mainly affects large joints like the hips and shoulders.

Gouty arthritis is an example of suppurative (pyogenic) arthritis.

Osteosarcomas can exhibit osteoblastic differentiation.

Ewing's sarcoma usually occurs in the diaphysis of long bones.

Rheumatoid arthritis is a systemic autoimmune collagen disease.

The affected joints in rheumatoid arthritis appear swollen and deformed.

Chondrosarcoma is the most common malignant bone tumor.

Metastatic tumors are more common than primary bone tumors.

Paget's disease of bone is a predisposing factor for osteosarcomas.