Human Pathology and X-linked SCID Overview

The process of identifying specific diseases through evaluation of signs and symptoms.

The process of cell death that is programmed and controlled, usually occurring in a single cell without causing damage to neighboring cells.

The process of cell death that is uncontrolled and messy, often damaging surrounding cells and triggering inflammation.

The intracellular accumulation of triglycerides, often associated with liver disease.

A condition characterized by an abnormal accumulation of iron in the body, often affecting organs like the liver and pancreas.

A programmed cell death triggered by cellular stress and DNA damage, involving the activation of p53.

The process of degrading unwanted or damaged cell components, often occurring in response to stress or lack of nutrients.

A type of cell death caused by inflammation, often triggered by bacterial infections.

The ability of a cell to divide indefinitely, often associated with cancer cells.

A gene that promotes cell growth and division, often mutated in cancer cells.

A gene that normally suppresses cell growth, but when mutated, can lead to cancer.

A protein that plays a key role in regulating the cell cycle, acting as a tumor suppressor.

A process that involves a series of steps that repair damaged DNA, preventing the development of cancer.

A type of cell death that occurs when cells lose contact with the extracellular matrix, often associated with cancer progression.

A special type of cell within a tumor that is able to self-renew and generate a heterogeneous population of cancer cells. These cells are often more resistant to chemotherapy.

A type of immune cell that helps fight infections and promote tissue repair.

Specialized antigen-presenting cells that activate T cells, playing a crucial role in initiating immune responses.

A type of white blood cell that is involved in the immune response to parasites and allergies.

A type of white blood cells that help fight bacterial infections.

A complex of proteins that activates caspase-9, leading to the execution phase of apoptosis.

A family of proteins that regulate the permeability of the mitochondrial outer membrane, playing a crucial role in apoptosis.

A process that involves the activation of caspases, resulting in the dismantling of the cell.

A harmful situation involving the formation of an abnormal deposit of protein in the body.

A form of inflammation characterized by the formation of granulomas, which are collections of immune cells that wall off foreign substances.

A type of macrophage that has been activated by exposure to cytokines and is involved in tissue repair and the resolution of inflammation.

Large cells with multiple nuclei, often found in granulomas.

A type of chronic inflammation that primarily affects the airways and is often associated with asthma.

The process of generating diversity in antibodies after an immune response, allowing the immune system to target a wider variety of antigens.

Cells that are capable of self-renewal and generating a variety of differentiated cell types.