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Questions and Answers
Which symbol is used to label a male that expresses a sex-linked disorder on a pedigree?
Which symbol is used to label a male that expresses a sex-linked disorder on a pedigree?
Based on the pedigree that is shown, John has hemophilia.
Based on the pedigree that is shown, John has hemophilia.
False
Fathers always determine the gender of the offspring in humans.
Fathers always determine the gender of the offspring in humans.
True
What is the purpose of using a pedigree?
What is the purpose of using a pedigree?
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How are the alleles for sex-linked traits inherited?
How are the alleles for sex-linked traits inherited?
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What was Thomas Hunt Morgan's main contribution to science?
What was Thomas Hunt Morgan's main contribution to science?
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What is the probability of the offspring having hemophilia for the given cross?
What is the probability of the offspring having hemophilia for the given cross?
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A patient who is Rh- can receive only Rh- blood.
A patient who is Rh- can receive only Rh- blood.
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Which Punnett square shows a cross in which the probability of offspring having red eyes is 100 percent?
Which Punnett square shows a cross in which the probability of offspring having red eyes is 100 percent?
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What is the probability that a female offspring would have a recessive allele for Duchenne muscular dystrophy disorder?
What is the probability that a female offspring would have a recessive allele for Duchenne muscular dystrophy disorder?
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What is the genotype for a recessive trait found on the female chromosome?
What is the genotype for a recessive trait found on the female chromosome?
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Which allele combination represents a female who is a carrier for an X-linked recessive disorder?
Which allele combination represents a female who is a carrier for an X-linked recessive disorder?
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The alleles for sex-linked inheritance are found on either the X or Y chromosome.
The alleles for sex-linked inheritance are found on either the X or Y chromosome.
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Which allele combination represents a female who is heterozygous for a sex-linked trait?
Which allele combination represents a female who is heterozygous for a sex-linked trait?
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Which pedigree symbol is used to represent a female carrier of a recessive X-linked trait?
Which pedigree symbol is used to represent a female carrier of a recessive X-linked trait?
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What is the probability that a female child of Charles and Marie would suffer from hemophilia?
What is the probability that a female child of Charles and Marie would suffer from hemophilia?
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Which combination of alleles are always involved in the inheritance of a sex-linked trait?
Which combination of alleles are always involved in the inheritance of a sex-linked trait?
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Study Notes
Sex-Linked Inheritance Key Concepts
- Male Symbol in Pedigree: Represented by a purple square (D) for individuals expressing a sex-linked disorder.
- Hemophilia in Pedigrees: An X-linked recessive disorder (Xh); John does not have hemophilia according to the analyzed pedigree.
- Gender Determination: In human offspring, fathers determine the gender.
- Purpose of Pedigree: Used to trace and understand the inheritance patterns of traits in organisms.
- Inheritance of Sex-Linked Traits: Passed from parents to offspring via the X and Y chromosomes.
Historical Insights
- Thomas Hunt Morgan's Contribution: Discovered the link between certain traits and the X chromosome.
Probability and Genetics
- Probability of Hemophilia: For specific crosses shown in a Punnett square, there is a 50 percent chance of offspring inheriting hemophilia.
- Duchenne Muscular Dystrophy: Affected female offspring from a given cross will definitely inherit the recessive allele (100 percent probability).
Genotype and Carrier Status
- Genotype for Recessive Trait in Females: Denoted as Xh.
- Allele Combination for Female Carriers: Represented as XRXr, indicating one normal and one recessive allele.
- Heterozygous Females: Also represented by XRXr for sex-linked traits.
Pedigree Symbols
- Carrier Symbol for Females: A half-filled circle (B) indicates a carrier of a recessive X-linked trait.
- Probability of Female Children with Hemophilia: In certain crosses, there is a 0 percent chance of a female child having hemophilia.
General Principles
- Allele Involvement in Sex-Linked Traits: Traits are inherited through alleles located on X and Y chromosomes.
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Description
Test your understanding of sex-linked inheritance through key concepts and examples. This quiz covers topics such as pedigree analysis and X-linked disorders like hemophilia. Challenge yourself with questions that reinforce your knowledge of genetic inheritance patterns.
