Human Genome Project Overview

<p>Whole genome shotgun sequencing (B)</p> Signup and view all the answers

<p>Mapped the entire human genome (A)</p> Signup and view all the answers

An international research effort that aimed to determine the complete DNA sequence of the human genome, involving the identification of all genes and the order of the three billion chemical base pairs in our DNA.

Identifying the estimated 20,000 to 25,000 genes within human DNA, determining the order of all three billion base pairs, storing this data in databases, improving tools for data analysis, transferring technologies to other fields, and addressing ethical, legal, and social implications.

Specialized cloning vectors, such as BACs (bacterial artificial chromosomes), were used to sequence large fragments of DNA. These fragments were then sequenced individually and ultimately assembled into a comprehensive map of human chromosomes.

The HGP significantly impacted the fields of medicine and biology by providing a complete blueprint of the human genome. This has revolutionized our understanding of genetic diseases and led to advancements in diagnosis, treatment, and prevention.

The enormous amount of data generated, equivalent to about 3,300 books filled with DNA sequences, posed significant challenges in storage and computation.