Human Genome Project Overview

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Questions and Answers

What was the primary objective of the Human Genome Project?

To create a vaccine for DNA diseases
To identify all 20,000-25,000 human genes (correct)
To develop new medical treatments
To analyze environmental impacts on human health

What was the estimated total cost of the Human Genome Project?

$9 billion (correct)
$3 billion
$1 billion
$12 billion

Which entities coordinated the Human Genome Project?

U.S. Department of Energy and National Institutes of Health (correct)
Centers for Disease Control and Prevention and National Academy of Sciences
World Health Organization and National Science Foundation
NASA and European Space Agency

What was one of the major methodologies used in the Human Genome Project?

<p>Whole genome shotgun sequencing (B)</p> Signup and view all the answers

What significant achievement did the Human Genome Project accomplish?

<p>Mapped the entire human genome (A)</p> Signup and view all the answers

Flashcards

What is the Human Genome Project (HGP)?

An international research effort that aimed to determine the complete DNA sequence of the human genome, involving the identification of all genes and the order of the three billion chemical base pairs in our DNA.

What were the main goals of the HGP?

Identifying the estimated 20,000 to 25,000 genes within human DNA, determining the order of all three billion base pairs, storing this data in databases, improving tools for data analysis, transferring technologies to other fields, and addressing ethical, legal, and social implications.

How were the methodologies used in the HGP?

Specialized cloning vectors, such as BACs (bacterial artificial chromosomes), were used to sequence large fragments of DNA. These fragments were then sequenced individually and ultimately assembled into a comprehensive map of human chromosomes.

What is the significance of the HGP?

The HGP significantly impacted the fields of medicine and biology by providing a complete blueprint of the human genome. This has revolutionized our understanding of genetic diseases and led to advancements in diagnosis, treatment, and prevention.

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Describe the size and cost of the HGP.

The enormous amount of data generated, equivalent to about 3,300 books filled with DNA sequences, posed significant challenges in storage and computation.

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