HP Chapter 4-  Cell Types and Tissue Organization
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Questions and Answers

Which of the following statements best describes how cells in the human body are organized?

  • Cells exist in a chaotic arrangement with no discernible pattern or structure.
  • Cells are organized into distinct types with identical functions, ensuring functional redundancy.
  • Cells are grouped into organized layers called tissues, reflecting their specific functions. (correct)
  • Cells are randomly distributed throughout the body, each operating independently.

What is the significance of the variety in cell shape within the human body?

  • Cell shape variation indicates genetic mutations within specific cells.
  • Cell shape variation reflects the diverse roles that cells perform in the body. (correct)
  • Cell shape is unrelated to cell function and is merely a result of random differentiation.
  • Cell shape determines the rate at which cells undergo mitotic division.

How does the organization of cells in tissue relate to diseases like cancer?

  • Cancer cells cause tissues to become more highly organized, increasing functional capacity.
  • Cancer cells have no impact on tissue organization, as they operate independently.
  • Cancer cells enhance tissue organization by promoting rapid cell division within defined layers.
  • Cancer causes a breakdown in the organized structure of tissues due to uncontrolled cell proliferation. (correct)

Considering that all cells in the human body originate from a single fertilized egg, what explains the existence of over 200 distinct cell types?

<p>The fertilized egg divides into cells, and the cells organize into tissues and commit to irreversible developmental pathways. (D)</p> Signup and view all the answers

If a researcher were to study tissue samples from different organs, what would be the most likely observation regarding cell types?

<p>Each tissue sample would exhibit a unique combination and arrangement of cell types, corresponding to the organ's specific function. (B)</p> Signup and view all the answers

Which characteristic is NOT typically used to classify tissues?

<p>Rate of cellular reproduction (D)</p> Signup and view all the answers

Which of the following best explains why multicellular protists are NOT considered to have tissues?

<p>Their cells are not organized to perform collective functions. (C)</p> Signup and view all the answers

How does histology aid in the diagnosis of diseases?

<p>By analyzing changes in tissue appearance, organization, and function. (B)</p> Signup and view all the answers

If a researcher is examining a slide containing multiple tissue types working together, what level of organization are they most likely observing?

<p>Organ (C)</p> Signup and view all the answers

Which of the following germ layers gives rise primarily to nervous tissue?

<p>Ectoderm (D)</p> Signup and view all the answers

Why are zygotes described as totipotent?

<p>They have the potential to develop into any cell type in the body. (D)</p> Signup and view all the answers

Which of the following is a primary function of connective tissue?

<p>Binding cells and organs together (D)</p> Signup and view all the answers

What is the role of hyaluronan in synovial fluid?

<p>To trap water and lubricate the joint. (D)</p> Signup and view all the answers

Which of the following is NOT a primary tissue type found in the human body?

<p>Skeletal Tissue (B)</p> Signup and view all the answers

Which type of membrane lines body cavities that open to the exterior environment?

<p>Mucous membrane (B)</p> Signup and view all the answers

Considering the function of epithelial tissue, where would you most likely find it?

<p>Lining the walls of the stomach (B)</p> Signup and view all the answers

What primary function does the mesothelium serve in serous membranes?

<p>Secreting a lubricating fluid. (B)</p> Signup and view all the answers

Which component of the cutaneous membrane provides protection against desiccation and pathogens?

<p>Dead, keratinized cells (D)</p> Signup and view all the answers

The pericardium is a serous membrane associated with which organ?

<p>Heart (D)</p> Signup and view all the answers

Which of the following describes the lamina propria's function in a mucous membrane?

<p>Providing structural support to the epithelial layer. (A)</p> Signup and view all the answers

If a patient has reduced hyaluronan production, which of the following would be a likely consequence?

<p>Decreased flexibility and increased friction in joints. (D)</p> Signup and view all the answers

Which of the following structures is formed solely from connective tissue?

<p>Synovial membrane (D)</p> Signup and view all the answers

What is the primary role of mesenteries formed by the peritoneum?

<p>Supporting and suspending digestive organs in the abdominal cavity (C)</p> Signup and view all the answers

Which embryonic layer is responsible for the development of the epithelium lining the cardiovascular system?

<p>Mesoderm (A)</p> Signup and view all the answers

What is a primary function of the cell junctions found in epithelial tissue?

<p>Forming specialized intercellular connections (B)</p> Signup and view all the answers

How do nutrients reach epithelial tissues, considering they are avascular?

<p>Diffusion or absorption from underlying tissues or the surface (D)</p> Signup and view all the answers

What is the role of the basement membrane in epithelial tissue?

<p>It separates the epithelium from underlying connective tissue and provides support (C)</p> Signup and view all the answers

Which of the following tissue types is characterized by a high cellular density and minimal extracellular matrix?

<p>Epithelial tissue (B)</p> Signup and view all the answers

Where would endothelium be located?

<p>Lining blood vessels (B)</p> Signup and view all the answers

What is the implication of rapid cell replacement in epithelial tissues for the human body?

<p>Enhanced ability to repair damaged tissues (D)</p> Signup and view all the answers

How does the polarity of epithelial cells contribute to their function?

<p>It allows differing functions on the apical and basal surfaces (D)</p> Signup and view all the answers

Which secretion method involves the exocytosis of vesicles containing secretory products?

<p>Merocrine secretion (D)</p> Signup and view all the answers

In which type of secretion does the entire cell rupture to release its contents?

<p>Holocrine secretion (C)</p> Signup and view all the answers

Which of the following describes apocrine secretion?

<p>Shedding of the apical portion of the cell, containing secretory products (B)</p> Signup and view all the answers

Which type of gland is characterized by a watery, enzyme-rich secretion?

<p>Serous gland (C)</p> Signup and view all the answers

A gland that releases both watery, enzyme-rich secretions and viscous, glycoprotein-rich secretions is classified as:

<p>Mixed exocrine gland (D)</p> Signup and view all the answers

How do holocrine glands replenish cells lost during secretion?

<p>By differentiating new gland cells from surrounding tissue (D)</p> Signup and view all the answers

Which of the following is an example of merocrine secretion?

<p>Secretion of sweat by eccrine glands (C)</p> Signup and view all the answers

What is the primary component of the secretion produced by mucous glands?

<p>Glycoprotein mucin (A)</p> Signup and view all the answers

What is the primary role of epithelial cells in controlling the passage of substances into the body?

<p>To act as a selective barrier, regulating which substances can cross. (A)</p> Signup and view all the answers

How do tight junctions contribute to the function of epithelial tissue as a selective barrier?

<p>By forming a complete seal between cells, blocking the paracellular movement of substances. (B)</p> Signup and view all the answers

What distinguishes hemidesmosomes from desmosomes in epithelial tissue?

<p>Hemidesmosomes link cells to the extracellular matrix, while desmosomes link cells to other cells. (C)</p> Signup and view all the answers

How do gap junctions facilitate coordinated activity in epithelial tissues?

<p>By allowing direct electrical and metabolic communication between adjacent cells. (B)</p> Signup and view all the answers

What is the functional significance of the mucociliary escalator in the respiratory tract?

<p>It propels mucus containing trapped particles towards the throat to be swallowed. (B)</p> Signup and view all the answers

How does the arrangement of cells in pseudostratified epithelium complicate its classification compared to simple or stratified epithelium?

<p>Pseudostratified epithelium consists of irregularly shaped cells where only one layer touches the basal lamina, but appears multilayered. (B)</p> Signup and view all the answers

What characteristic is associated with simple squamous epithelium that makes it well-suited for the exchange of materials?

<p>Its thin, single-layered structure allows for rapid diffusion. (C)</p> Signup and view all the answers

If a patient's airway cilia are damaged due to smoking, what is the most likely consequence?

<p>Increased susceptibility to respiratory infections due to impaired clearance of mucus and debris. (C)</p> Signup and view all the answers

How would the function of the small intestine be affected if its epithelial cells lost their ability to secrete digestive enzymes?

<p>Digestion would be less efficient, leading to malabsorption of nutrients. (C)</p> Signup and view all the answers

What is the primary function of the mesothelium lining body cavities and internal organs?

<p>To provide a smooth, protective surface that reduces friction. (D)</p> Signup and view all the answers

What is a key difference between adherens junctions that link to other cells versus those that link to the matrix?

<p>Adherens junctions linking to the matrix use integrins, while those linking to other cells use cadherins. (A)</p> Signup and view all the answers

How does the polarized distribution of organelles in epithelial cells relate to their function?

<p>Polarization ensures that specific functions are localized to particular regions of the cell, optimizing its role.. (C)</p> Signup and view all the answers

Which type of epithelial cell junction is most important for enabling epithelial tissue to withstand mechanical stress and maintain structural integrity?

<p>Anchoring junctions, like desmosomes, because they provide strong and flexible connections. (C)</p> Signup and view all the answers

If a drug is designed to selectively block the function of cadherins, which type of epithelial cell junction would be most directly affected?

<p>Desmosomes. (A)</p> Signup and view all the answers

If a researcher observes an epithelial tissue with cells that appear box-like and have nuclei located in the center, what cell shape would they classify it as?

<p>Cuboidal. (D)</p> Signup and view all the answers

How does the arrangement of cells in pseudostratified columnar epithelium contribute to its function in the respiratory tract?

<p>The cilia on the apical surface trap and propel particulate matter away from the lungs. (C)</p> Signup and view all the answers

What functional advantage does transitional epithelium provide in the urinary bladder?

<p>Its ability to stretch and thin accommodates volume fluctuations. (B)</p> Signup and view all the answers

How do endocrine glands differ structurally and functionally from exocrine glands?

<p>Endocrine glands are ductless and secrete hormones into the bloodstream, while exocrine glands have ducts and secrete onto epithelial surfaces. (D)</p> Signup and view all the answers

Why is the classification of stratified epithelium based on the shape of cells in the apical layer?

<p>Apical cells are closest to the external environment and perform protective functions. (D)</p> Signup and view all the answers

What is the functional significance of goblet cells being interspersed among the columnar epithelial cells in the lining of the intestine?

<p>To secrete mucus, which protects and lubricates the lining. (B)</p> Signup and view all the answers

How does the presence or absence of keratin affect the function of stratified squamous epithelium?

<p>Keratin provides a waterproof barrier in dry environments, while non-keratinized epithelium is found in moist environments. (A)</p> Signup and view all the answers

If a patient's thyroid gland is underproducing hormones, which type of gland is likely malfunctioning?

<p>An endocrine gland. (A)</p> Signup and view all the answers

Considering their respective functions, where would you expect to find simple squamous epithelium?

<p>Lining of blood vessels for efficient gas exchange. (C)</p> Signup and view all the answers

What is the key structural difference between simple and compound tubular exocrine glands?

<p>Simple glands have a single, unbranched duct, while compound glands have a branched duct. (D)</p> Signup and view all the answers

How does the function of ciliated columnar epithelium in the fallopian tubes relate to its cellular structure?

<p>The cilia propel the egg towards the uterus. (D)</p> Signup and view all the answers

In tubuloalveolar glands, how do the tubular and alveolar (acinar) portions contribute to the gland's overall function?

<p>Tubules modify secretions, while alveoli produce them. (C)</p> Signup and view all the answers

When observing a tissue sample under a microscope, how could you differentiate between simple columnar and pseudostratified columnar epithelium?

<p>By the arrangement of nuclei; simple columnar has nuclei at the same level, while pseudostratified has nuclei at varying levels. (A)</p> Signup and view all the answers

How does the location of glands within the body (e.g., lining of the gastrointestinal tract versus the anterior pituitary) relate to their classification as endocrine or exocrine?

<p>Glands that release secretions into a duct leading to an external surface or the lumen of an organ are exocrine, while those that release directly into the bloodstream are endocrine. (D)</p> Signup and view all the answers

What functional challenges might arise if the transitional epithelium in the urinary bladder were replaced by stratified squamous epithelium?

<p>The bladder would lose its ability to stretch and accommodate volume changes, potentially causing increased pressure and discomfort. (A)</p> Signup and view all the answers

How might damage to the ducts of a multicellular exocrine gland affect its function, and what secondary effects might this have on the body?

<p>Damage to ducts of exocrine glands would lead to accumulation of secretions within the gland, potentially causing inflammation and disrupting the delivery of necessary substances to target areas. (D)</p> Signup and view all the answers

Connective tissues share common components, but their specific structure varies. Which of the following best explains how this structural variation supports the diverse functions of connective tissues?

<p>Variations in the composition and organization of the ground substance and protein fibers within the matrix are optimized for specific functional demands. (A)</p> Signup and view all the answers

If a patient has a condition that impairs the function of fibroblasts, which of the following consequences would most directly affect connective tissue?

<p>Decreased production of the extracellular matrix. (A)</p> Signup and view all the answers

Mesenchyme is a type of embryonic connective tissue. What is the primary significance of mesenchymal cells persisting in small numbers within adult tissues?

<p>They provide a reserve pool of cells for tissue repair and replacement. (B)</p> Signup and view all the answers

How do specialized fluid connective tissues, like blood and lymph, contribute to the overall function of the body beyond simply connecting structures?

<p>They facilitate the transport of fluids, nutrients, waste, and chemical messengers. (C)</p> Signup and view all the answers

Considering the role of connective tissue in protection, how does the skeletal system exemplify this function?

<p>By acting as bones that protect delicate organs. (A)</p> Signup and view all the answers

Adipose tissue is a type of connective tissue. How does adipose tissue contribute to thermal insulation for the body?

<p>By storing surplus energy in the form of fat. (C)</p> Signup and view all the answers

If a developing embryo experienced impaired mesodermal development, which of the following types of tissues would be most directly affected?

<p>Connective tissues throughout the body. (A)</p> Signup and view all the answers

Wharton's jelly is a type of embryonic connective tissue found in the umbilical cord. What happens to Wharton's jelly after birth?

<p>It is no longer present, leaving scattered mesenchymal cells. (A)</p> Signup and view all the answers

Which characteristic of cartilage contributes most significantly to its slow healing process?

<p>The avascular nature, requiring nutrients to diffuse through the matrix. (B)</p> Signup and view all the answers

What would be the most likely effect on bone tissue if collagen production was severely impaired?

<p>Bones would become brittle and prone to fracture. (D)</p> Signup and view all the answers

Which of the following best explains why elastic cartilage is found in the ear but hyaline cartilage is found connecting ribs to the sternum?

<p>Elastic cartilage provides support and the ability to return to its original shape after deformation, while hyaline cartilage provides strong, flexible support. (A)</p> Signup and view all the answers

How do lymphatic capillaries contribute to maintaining fluid balance in the body?

<p>By absorbing excess fluid and molecules from interstitial spaces. (D)</p> Signup and view all the answers

What is the functional significance of the arrangement of osteocytes in concentric circles around a central canal in compact bone?

<p>All of the above. (D)</p> Signup and view all the answers

Which of the following is a critical distinction between compact and cancellous bone that contributes to their different functions?

<p>Compact bone is solid and dense, providing strength, while cancellous bone is spongy and lightweight, providing space for bone marrow. (A)</p> Signup and view all the answers

How does the structure of fibrocartilage align with its function in the intervertebral discs?

<p>The thick bundles of collagen fibers provide resistance to compression and tension. (D)</p> Signup and view all the answers

How do erythrocytes contribute to the homeostasis of the human body?

<p>By transporting oxygen and carbon dioxide. (A)</p> Signup and view all the answers

Considering the functions of blood as a connective tissue, what would happen if the bone marrow was unable to produce leukocytes?

<p>The body's ability to fight infections would be compromised. (B)</p> Signup and view all the answers

How does the presence of hydroxyapatite in bone matrix contribute to the overall function of bone tissue?

<p>It gives bone its hardness and resistance to compression. (D)</p> Signup and view all the answers

Which characteristic distinguishes dense connective tissue from loose connective tissue?

<p>The arrangement and density of protein fibers within the matrix. (B)</p> Signup and view all the answers

How do fibroblasts contribute to the structure of connective tissue proper?

<p>They secrete polysaccharides and proteins that form the ground substance and extracellular matrix. (B)</p> Signup and view all the answers

Which of the following best describes the function of macrophages in connective tissue?

<p>Defending against pathogens and removing cellular debris. (B)</p> Signup and view all the answers

How do mast cells contribute to the inflammatory response in connective tissue?

<p>By releasing histamine, which causes vasodilation and increased blood flow. (B)</p> Signup and view all the answers

What is the primary role of elastic fibers in connective tissue?

<p>Allowing tissues to return to their original shape after being stretched. (C)</p> Signup and view all the answers

How do reticular fibers support the structure of organs like the liver and spleen?

<p>By forming a branching network that anchors and supports functional cells. (A)</p> Signup and view all the answers

What is the role of ground substance in connective tissue?

<p>To act as a medium for diffusion of nutrients and waste, and to cushion and protect the tissue. (D)</p> Signup and view all the answers

How do mesenchymal cells contribute to the repair of damaged connective tissue?

<p>They differentiate into the types of connective tissue cells needed for repair. (B)</p> Signup and view all the answers

What is the main difference between white and brown adipocytes?

<p>White adipocytes store lipids as a single large drop and are metabolically less active, while brown adipocytes store lipids as many droplets and have high metabolic activity. (D)</p> Signup and view all the answers

Where is loose connective tissue typically found, and what is its function?

<p>Between many organs, acting as a shock absorber and binding tissues together. (A)</p> Signup and view all the answers

Which type of fiber provides ligaments and tendons with their characteristic resilience and strength?

<p>Collagen Fiber (C)</p> Signup and view all the answers

What is the function of cytokines that are released by macrophages?

<p>To recruit other immune cells to infected sites and stimulate their activities. (D)</p> Signup and view all the answers

How does the arrangement of collagen fibers contribute to the overall function of dense regular connective tissue?

<p>Regular arrangement of fibers allows for high tensile strength in one direction. (D)</p> Signup and view all the answers

What is the significance of hyaluronic acid in the ground substance of connective tissue?

<p>It attracts and traps moisture, contributing to the viscous nature of the ground substance. (D)</p> Signup and view all the answers

What is the role of hematopoietic stem cells in the context of connective tissue?

<p>Like blood cells, they differentiate into mast cells, important in the inflammatory response. (B)</p> Signup and view all the answers

Which of the following is a primary function of white adipose tissue?

<p>Storing lipids for energy and insulation. (A)</p> Signup and view all the answers

What characteristic of brown adipose tissue allows it to efficiently metabolize stored fat?

<p>Numerous mitochondria in the cytoplasm. (A)</p> Signup and view all the answers

In what way does brown adipose tissue differ from other tissues in its metabolism of fats?

<p>It releases metabolic heat instead of producing ATP. (D)</p> Signup and view all the answers

Which of the following locations is NOT a typical site for finding areolar connective tissue?

<p>In the supportive framework of the spleen. (C)</p> Signup and view all the answers

What is the main function of reticular tissue?

<p>To support soft organs like the liver and spleen. (D)</p> Signup and view all the answers

How does the arrangement of collagen fibers in dense irregular connective tissue contribute to its function?

<p>It gives the tissue strength in multiple directions. (B)</p> Signup and view all the answers

Which of the following tissues contains elastin fibers that allows a ligament to return to its original length after stretching?

<p>Dense regular elastic. (C)</p> Signup and view all the answers

What is the underlying cause of tendinitis?

<p>Inflammation due to repetitive strain on a tendon. (D)</p> Signup and view all the answers

Why are individuals who perform repetitive motions at greater risk of developing tendinitis?

<p>Repetitive motions cause microtrauma and inflammation in the tendons. (B)</p> Signup and view all the answers

Why might X-rays be used in diagnosing tendinitis?

<p>To rule out the possibility of a bone injury. (B)</p> Signup and view all the answers

Why do tendon injuries typically heal slowly?

<p>Tendons have a limited blood supply, which impairs the delivery of nutrients and immune cells. (C)</p> Signup and view all the answers

Which of the following is NOT a recommended measure to prevent tendinitis?

<p>Maintaining a constant, repetitive workout routine. (C)</p> Signup and view all the answers

Which statement accurately describes a key difference between ligaments and tendons, both made of dense regular connective tissue?

<p>Ligaments have fibers that are not always parallel, providing more flexibility than tendons. (A)</p> Signup and view all the answers

A pathologist is examining a tissue sample and notes that the collagen fibers are aligned in a parallel fashion. Furthermore, fibroblasts are sparsely distributed between these fibers. Which type of tissue is the pathologist most likely observing?

<p>Dense regular connective tissue. (C)</p> Signup and view all the answers

In the walls of large arteries, such those closest to the heart, which type of connective tissue would be most prevalent and why?

<p>Dense irregular elastic tissue, to withstand pressure and regain original shape after stretching. (C)</p> Signup and view all the answers

If a toxin disrupts the function of attachment junctions in cardiac muscle, which of the following is the most likely consequence?

<p>Compromised ability of cardiac tissue to withstand pressure changes. (D)</p> Signup and view all the answers

Which of the following physiological changes would most likely result from impaired smooth muscle function in the digestive system?

<p>Difficulty in the propulsion of food through the gastrointestinal tract. (B)</p> Signup and view all the answers

A researcher is comparing microscopic images of muscle tissues. What key feature would allow them to definitively identify smooth muscle tissue?

<p>Spindle-shaped cells with a single, centrally located nucleus and no visible striations. (B)</p> Signup and view all the answers

Damage to smooth muscle in the walls of arteries is most likely to directly impair which of the following functions?

<p>Regulation of blood pressure through vasoconstriction and vasodilation. (C)</p> Signup and view all the answers

A patient has difficulty controlling the movement of food through their esophagus. Which type of muscle tissue is most likely affected?

<p>Smooth muscle, responsible for involuntary movements in internal organs. (C)</p> Signup and view all the answers

Which of the following characteristics is shared by both skeletal and cardiac muscle tissue?

<p>Striated appearance under a microscope (B)</p> Signup and view all the answers

The ability of muscle tissue to respond to a stimulus is known as:

<p>Excitability (A)</p> Signup and view all the answers

What cellular process explains the multinucleated nature of skeletal muscle fibers?

<p>Fusion of myoblasts (C)</p> Signup and view all the answers

Which type of muscle tissue contributes most significantly to thermoregulation through shivering?

<p>Skeletal muscle (B)</p> Signup and view all the answers

What is the primary function of intercalated discs in cardiac muscle tissue?

<p>To facilitate rapid communication and coordinated contraction (A)</p> Signup and view all the answers

Which of the following best describes the arrangement of skeletal muscle tissue?

<p>Bundles of cells surrounded by connective tissue (C)</p> Signup and view all the answers

Assuming that myocytes are responsible for muscle contraction, which statement is most accurate regarding the number of myocytes a person has?

<p>Myocyte number is remains relatively constant throughout ones life. (B)</p> Signup and view all the answers

Which of the following explains why cardiac muscle does not require external nervous stimulation to initiate contraction?

<p>Cardiac muscle possesses intrinsic rhythmicity. (C)</p> Signup and view all the answers

What would be the most likely consequence if oligodendrocytes in the central nervous system were damaged?

<p>Impaired formation of myelin sheath around axons in the brain and spinal cord. (C)</p> Signup and view all the answers

In a patient experiencing peripheral nerve damage, which cells would be primarily involved in the regeneration and myelination of the affected neurons?

<p>Schwann cells (D)</p> Signup and view all the answers

How does the myelination process performed by Schwann cells differ fundamentally from that of oligodendrocytes?

<p>Schwann cells myelinate a single axon, whereas oligodendrocytes can myelinate multiple axons. (A)</p> Signup and view all the answers

What is a key functional difference resulting from the distinct locations and myelination patterns of oligodendrocytes and Schwann cells?

<p>Schwann cells are able to support axonal regeneration after injury, while oligodendrocytes generally do not. (D)</p> Signup and view all the answers

A researcher is comparing the lipid composition of myelin sheaths from the brain and the sciatic nerve. What would be a valid hypothesis regarding the composition of these samples?

<p>The lipid composition will significantly differ due to the different cell types (oligodendrocytes vs. Schwann cells) and their local microenvironments. (A)</p> Signup and view all the answers

How do neuroglia support neurons in the nervous system?

<p>By providing structural support and modulating information propagation. (D)</p> Signup and view all the answers

What structural feature is characteristic of multipolar neurons?

<p>Several dendrites and a single axon extending from the cell body. (C)</p> Signup and view all the answers

How do astrocytes contribute to the function of the nervous system?

<p>By regulating ion concentrations and forming the blood-brain barrier. (D)</p> Signup and view all the answers

Which cellular component is responsible for propagating the electrochemical signal (action potential / nerve impulse) away from the neuron cell body?

<p>The axon, which transmits the signal to the next cell. (C)</p> Signup and view all the answers

Which of the following is a key characteristic of nervous tissue?

<p>Excitable and capable of sending electrochemical signals. (B)</p> Signup and view all the answers

How does the myelin sheath contribute to neuronal function?

<p>By providing an insulating layer around axons. (B)</p> Signup and view all the answers

Which type of cell in nervous tissue is NOT considered nervous tissue but functions in immune defense?

<p>Microglia. (C)</p> Signup and view all the answers

At a synapse, what process directly leads to a response in the target cell?

<p>The binding of neurotransmitters to receptors on the target cell. (D)</p> Signup and view all the answers

If a patient is diagnosed with a sarcoma, from which primary tissue type did the cancer most likely originate?

<p>Connective tissue (D)</p> Signup and view all the answers

Why are traditional cancer treatments like chemotherapy often associated with significant side effects?

<p>They cannot distinguish between rapidly dividing cancer cells and healthy cells. (C)</p> Signup and view all the answers

How do cancer stem cells contribute to the complexity of cancer treatment?

<p>They represent a specific subtype of cell responsible for the uncontrolled growth of tumors. (A)</p> Signup and view all the answers

Which of the following best describes the current understanding of tumor structure?

<p>Tumors possess their own structures, challenging previous assumptions of disorganization. (B)</p> Signup and view all the answers

A researcher is developing a new cancer therapy that targets specific proteins implicated in cancer-associated molecular pathways. What is the primary goal of this approach?

<p>To selectively kill cancer cells while minimizing harm to healthy cells. (C)</p> Signup and view all the answers

Which cellular process is LEAST likely to trigger an inflammatory response in adjacent tissues?

<p>Programmed cell death during embryonic development. (D)</p> Signup and view all the answers

A patient presents with peritonitis. Based on your understanding of medical terminology, what area is inflamed?

<p>The membrane lining the abdominal cavity. (D)</p> Signup and view all the answers

Following a minor cut, a patient experiences localized redness and warmth. Which physiological change accounts for these signs of inflammation?

<p>Vasodilation of blood vessels at the site of injury. (D)</p> Signup and view all the answers

A researcher is investigating the effect of a new drug on inflammation. Which of the following would indicate that the drug successfully reduced vascular permeability at the site of inflammation?

<p>Decreased edema in the affected tissue. (A)</p> Signup and view all the answers

What is the role of histamine in the initial stages of inflammation?

<p>To increase blood vessel dilation. (A)</p> Signup and view all the answers

If a patient has a mutation that impairs the function of mast cells, which aspect of the inflammatory response would be most directly affected?

<p>The initial vasodilation and increased vascular permeability. (C)</p> Signup and view all the answers

Which of the following best explains the role of prostaglandins in the inflammatory response?

<p>Sensitizing pain neurons, leading to the sensation of pain. (A)</p> Signup and view all the answers

A patient with chronic arthritis experiences persistent joint pain and inflammation. Which of the following accurately describes the underlying issue in chronic inflammation?

<p>The inflammatory response persists over time, leading to diseased conditions. (B)</p> Signup and view all the answers

How do non-steroidal anti-inflammatory drugs (NSAIDs) alleviate pain?

<p>By inhibiting the synthesis of prostaglandins, which are involved in inflammation and pain. (A)</p> Signup and view all the answers

What is the role of fibroblasts during the tissue repair phase?

<p>To replace the collagen and extracellular material lost due to injury. (B)</p> Signup and view all the answers

How does angiogenesis contribute to the healing process?

<p>It results in vascularization of new tissue, forming granulation tissue. (A)</p> Signup and view all the answers

What is the primary difference between primary and secondary union in wound healing?

<p>Primary union occurs when wound edges are close together, while secondary union occurs when there is a gaping wound. (B)</p> Signup and view all the answers

What cellular change causes hair to turn gray with age?

<p>Hair follicles producing less melanin. (B)</p> Signup and view all the answers

Which of the following best explains why skin loses elasticity with age?

<p>Decreased elasticity is due to thinner, drier tissues and reduced elastic and collagen fibers. (B)</p> Signup and view all the answers

Which cellular process is directly affected by the shortening of telomeres during aging?

<p>Decreased ability of cells to divide and regenerate. (A)</p> Signup and view all the answers

How do alterations in cell membranes contribute to the aging process?

<p>By hindering the transport of oxygen and nutrients into the cell and removal of carbon dioxide and waste products. (A)</p> Signup and view all the answers

What is a key difference between benign and malignant tumors?

<p>Malignant tumors breach the confines of their tissue and metastasize, while benign tumors do not. (D)</p> Signup and view all the answers

What is the significance of angiogenesis in the development of malignant tumors?

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How is a mutation defined in the context of cancer development?

<p>A permanent change in the DNA of a cell. (C)</p> Signup and view all the answers

What is the role of clotting (coagulation) in tissue repair?

<p>To reduce blood loss from damaged vessels and bind the edges of the wound together. (A)</p> Signup and view all the answers

How do antihistamines work to decrease allergies?

<p>By blocking histamine receptors, reducing the histamine response. (A)</p> Signup and view all the answers

What initiates the tissue repair phase after an injury?

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In the context of uncontrolled cell growth, what is the 'hallmark' of cancer?

<p>Uncontrolled growth, invasion into adjacent tissues, and colonization of other organs. (B)</p> Signup and view all the answers

If parathyroid hormone (PTH) levels increase, how would the skeletal system respond to restore calcium homeostasis?

<p>By promoting osteoclast activity to release calcium into the bloodstream. (B)</p> Signup and view all the answers

How does the kidney contribute to calcium homeostasis in conjunction with the skeletal system?

<p>By activating vitamin D, which promotes calcium absorption in the intestine. (D)</p> Signup and view all the answers

What effect would long-term hypercalcemia, due to excessive calcium supplementation, have on bone remodeling?

<p>Decreased bone density due to suppressed PTH secretion and reduced osteoblast activity. (C)</p> Signup and view all the answers

Which of the following scenarios would most likely result in increased calcium deposition in bone?

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How do hormones such as calcitonin contribute to the regulation of calcium levels in the body?

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Which type of muscle tissue contains cells that are both striated and under involuntary control?

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Myocytes, which are the cells of muscle tissue, directly develop from which type of precursor cells?

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Given the high energy demands of skeletal muscle, which organelle would you expect to be most abundant in skeletal muscle cells?

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Which type of central nervous system cell is crucial for maintaining the blood-brain barrier and regulating the microenvironment around neurons?

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During an inflammatory response, mast cells release specific chemicals to initiate the process. Which of the following chemicals is released by mast cells to promote inflammation?

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Which of the following is the MOST accurate regarding embryonic tissue's role in the human body?

<p>It is crucial during development, giving rise to more specialized tissue types. (B)</p> Signup and view all the answers

Which of the following properties are critical for simple squamous epithelium's function in places such as the lining of blood vessels and air sacs of the lungs?

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Cilia are essential to the function of pseudostratified ciliated columnar epithelium. What is the MOST likely consequence if cilia are damaged?

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How do holocrine and apocrine glands differ in their mechanisms of secretion and subsequent impact on the secreting cell?

<p>Holocrine glands rupture and release their contents, destroying the cell, while apocrine glands release their apical region and then repair themselves. (C)</p> Signup and view all the answers

Which of the following explains how the three essential components of connective tissue work together to give connective tissue its diverse functions?

<p>Cells produce the ground substance and protein fibers, which collectively determine the tissue's properties. (C)</p> Signup and view all the answers

A pathologist observes a tissue sample with cells suspended in a transparent background. How can they be MOST confident that the tissue is hyaline cartilage rather than loose connective tissue?

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Ligaments and tendons are under a lot of stress. How does the structural organization of dense regular connective tissue help them withstand these forces?

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In bone tissue, osteocytes are the main cells. Which of the following cellular activities performed by osteocytes is critical for maintaining bone health and structural integrity?

<p>Maintaining the mineral content and sensing mechanical stress. (B)</p> Signup and view all the answers

Which of the following examples best describes how the structure of the mucosa aligns with its function in nutrient absorption?

<p>The presence of microvilli on the apical surface of epithelial cells increases surface area for absorption. (A)</p> Signup and view all the answers

How does blood fulfill the role of integrating various organs and organ systems within the body?

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What is the primary reason hyaline cartilage heals much slower than a bone fracture?

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Based on the observation of spontaneously contracting cells in a dish that eventually synchronize, what type of cells are you most likely observing?

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Which morphological adaptation of neurons is most critical for the rapid transmission of nerve impulses?

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Why is it important to monitor for increased redness, swelling, and pain after cleaning and bandaging a cut or abrasion?

<p>These signs may indicate an infection or excessive inflammation, potentially delaying healing. (C)</p> Signup and view all the answers

Considering the role of inflammation in the body's response to infection, what is a potential undesirable consequence of regularly taking anti-inflammatory drugs?

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Which of the following contributes most significantly to the decline in an individual's physiological functioning with age?

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Flashcards

Cell Types

The human body contains over 200 different kinds.

Tissue

Cells are arranged in organized layers to form a tissue.

Cell Shape Variation

Cells vary greatly in shape, which reflects their different functions.

Cell Specialization

Cells commit to a specific developmental pathway, leading to specialized functions.

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Tissue Organization

The body consists of cells arranged into tissues.

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What is a Tissue?

A group of cells found together in the body that share a common embryonic origin and function.

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Four Tissue Types

Epithelial, connective, muscle, and nervous.

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Epithelial Tissue

Covers body surfaces, lines cavities and forms glands.

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Connective Tissue

Binds cells/organs, provides protection, support, and integration.

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Muscle Tissue

Responds to stimulation & contracts to provide movement.

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Nervous Tissue

Propagates electrochemical signals for communication.

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Histology

Microscopic study of tissue appearance, organization, and function.

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Totipotent Cells

Can differentiate into ANY type of cell in the body.

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Ectoderm

The outermost germ layer; gives rise to the nervous system and epidermis.

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Mesoderm

The middle germ layer; develops into muscle, bone, blood, and connective tissues.

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Endoderm

The innermost germ layer; forms the lining of the digestive tract and associated organs.

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Tissue Membrane

A thin layer or sheet of cells covering the body's exterior, lining internal passageways and cavities.

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Connective Tissue Membrane

Membranes formed solely from connective tissue, encapsulating organs and lining movable joints.

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Synovial Membrane

A type of connective tissue membrane lining the cavity of freely movable joints, producing synovial fluid.

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Synovial Fluid

Fluid produced by the synovial membrane; lubricates joints, reducing friction.

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Epithelial Membrane

Membrane composed of epithelium attached to a layer of connective tissue, such as skin.

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Mucous Membrane

Epithelial membranes lining body cavities and passageways open to the external environment; includes digestive and respiratory tracts; secretes mucus.

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Serous Membrane

Epithelial membrane composed of mesothelium supported by connective tissue lining coelomic cavities; secretes serous fluid.

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Endothelium

A type of epithelium that lines hollow organs and body cavities that do not connect to the exterior.

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Ectoderm-derived Epithelium

The embryonic layer that gives rise to the epithelia lining the skin, mouth, and anus.

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Endoderm-derived Epithelium

The embryonic layer that forms the epithelium lining the airways and most of the digestive system.

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Cell Junctions

Specialized intercellular connections between cell membranes in epithelial tissues.

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Epithelial Polarity

The difference in structure and function between the exposed (apical) and basal surfaces of epithelial cells.

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Basal Lamina

A mixture of glycoproteins and collagen that provides an attachment site for epithelium.

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Avascularity of Epithelia

Epithelial tissues lack blood vessels, requiring nutrients to come from underlying tissues or the surface.

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Epithelial Function

Epithelial cells control what enters the body.

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Epithelial Secretion

Release of mucous or chemical compounds onto the cell surface.

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Epithelial Cilia

Microscopic extensions to move fluids/particles.

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Mucociliary Escalator

Moves trapped particles toward the throat.

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Tight Junctions

Prevent substance movement between cells.

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Anchoring Junctions

Stabilize epithelial tissues.

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Desmosomes

Link cells; adhesion molecule is cadherin.

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Hemidesmosomes

Link cells to extracellular matrix; adhesion protein integrins.

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Adherens Junctions

Type of cell junctions using cadherins or integrins, containing actin.

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Gap Junctions

Allows small molecules to pass between cells.

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Squamous Cells

Flattened and thin cells.

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Cuboidal Cells

Boxy cells, as wide as tall.

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Columnar Cells

Rectangular cells, taller than wide.

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Simple Epithelium

Single layer of cells.

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Exocrine Glands

Glands that secrete substances through ducts onto epithelial surfaces.

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Merocrine Secretion

Secretion via exocytosis; most common type; no cell damage.

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Apocrine Secretion

Secretion where apical portion of cell pinches off, releasing contents.

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Holocrine Secretion

Secretion involving rupture and destruction of the entire gland cell.

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Serous Gland

Produces watery secretions rich in enzymes (like alpha amylase).

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Mucous Gland

Releases watery to viscous (thick) products rich in mucin.

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Mixed Exocrine Glands

Glands containing both mucous and serous glands, releasing both types of secretions.

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Sebaceous Glands

Glands that produce oils on the skin and hair using holocrine secretion.

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Simple Cuboidal Epithelium

Single layer of cube-shaped cells, round nucleus in the center.

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Simple Columnar Epithelium

Single layer of column-like cells, elongated nucleus near the base.

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Ciliated Columnar Epithelium

Simple columnar epithelium with cilia on their apical surfaces.

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Pseudostratified Columnar Epithelium

Appears stratified but is a single layer of irregularly shaped columnar cells.

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Goblet Cell

A mucous-secreting unicellular gland among columnar epithelial cells.

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Stratified Epithelium

Epithelium with multiple stacked layers of cells.

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Stratified Squamous Epithelium

Apical cells are squamous, basal cells are columnar or cuboidal; may be keratinized.

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Transitional Epithelium

A stratified epithelium in the urinary system with cells that change shape as bladder fills.

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Gland

Structure made of one or more cells that synthesize and secrete substances.

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Endocrine Gland

Ductless gland that releases secretions directly into surrounding tissues/fluids.

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Hormone

Secretion of endocrine glands released into interstitial fluid and diffused into bloodstream.

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Unicellular Exocrine Glands

Single-celled exocrine glands scattered in mucous membranes.

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Multicellular Tubular Glands

Multicellular exocrine glands release their contents through a tubular duct.

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Connective Tissue Function

Connects tissues and organs.

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Connective Tissue Structure

Cells dispersed in a matrix containing ground substance and protein fibers.

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Ground Substance

Fluid, mineralized, or solid material surrounding connective tissue cells.

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Connective Tissue Functions

Support, connect, protect, transport, and store energy.

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Connective Tissue Examples

Sheaths, tendons, skeleton; capsules and bones; blood and lymph; adipose cells.

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Immune Function

Defense against microorganisms.

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Connective Tissue Transport

Fluid connective tissues transport nutrients, waste, and chemical messengers.

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Mesenchyme

Stem cell line from which all connective tissues derive.

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Connective Tissue Proper

Includes loose and dense types; has cells and fibers in a viscous ground substance.

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Supportive Connective Tissue

Provides structure and strength; includes bone and cartilage.

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Fluid Connective Tissue

Transports substances; includes lymph and blood with cells in a watery fluid.

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Fibroblast

Most abundant cell in connective tissue proper; secretes matrix components.

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Fibrocyte

Less active form of fibroblast; maintains connective tissue matrix.

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Adipocytes

Cells that store lipids as droplets; white and brown types exist.

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Mesenchymal Cell

Adult stem cell that can differentiate into various connective tissue cells.

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Macrophage

Large immune cell derived from monocyte; engulfs pathogens and debris.

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Mast Cell

Releases histamine and heparin, causing inflammation during allergic responses.

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Collagen Fiber

Strong, flexible fibers that resist stretching; made of collagen protein.

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Elastic Fiber

Fibers containing elastin; return to original shape after stretching.

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Reticular Fiber

Narrow fibers forming a branching network; support soft organs.

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Loose Connective Tissue

Acts as shock absorber and diffusion medium between organs.

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Adipose Tissue

Tissue with many fat storage cells and few matrix. Stores & mobilizes lipids.

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White Adipose Tissue

Primarily for lipid storage, insulation, and protection.

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Brown Adipose Tissue

Common in infants; metabolizes fat to release heat.

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Thermogenic Tissue

Breaks down fats to release heat.

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Areolar Tissue

Fills spaces, surrounds vessels, supports organs.

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Reticular Tissue

Supportive meshwork for soft organs.

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Dense Connective Tissue

Resists stretching; more collagen than loose connective tissue.

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Dense Regular Connective Tissue

Fibers are parallel, high tensile strength.

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Dense Regular Elastic Tissue

Allows tissue to return to original length after stretching.

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Dense Irregular Connective Tissue

Fibers are randomly arranged, strength in all directions.

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Tendinitis

Inflammation of a tendon due to repetitive strain.

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Tendon

Connects muscle to bone.

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Tendinitis Cause

Repetitive motions cause microtrauma and inflammation.

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Tendinitis Treatment

Rest, ice, anti-inflammatory medication.

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Tendinitis Prevention

Stretches, cross-training, improving technique.

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Chondroitin Sulfates

Polysaccharides in cartilage that bind to proteins forming proteoglycans.

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Chondrocytes

Cartilage cells located within the cartilage matrix.

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Lacunae (Cartilage)

Spaces within the cartilage matrix where chondrocytes reside.

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Perichondrium

A layer of dense irregular connective tissue that surrounds cartilage.

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Hyaline Cartilage

Most common cartilage; found in ribs, nose and joints; provides smooth surfaces for movement.

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Fibrocartilage

Cartilage with thick collagen bundles; found in menisci and intervertebral discs; resists compression.

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Elastic Cartilage

Cartilage containing elastic fibers; found in the external ear; provides flexible support.

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Osteocytes

Mature bone cells located within lacunae.

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Hydroxyapatite

The primary mineral component of bone, containing calcium phosphate.

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Blood

Fluid connective tissue containing erythrocytes, leukocytes, and platelets.

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Cardiac Muscle

Muscle tissue that pumps blood, operating involuntarily.

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Attachment Junctions (Cardiac)

Specialized cell connections that hold cardiac cells together during pressure changes.

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Smooth Muscle Tissue

Muscle tissue responsible for involuntary movements in internal organs.

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Smooth Muscle Cells

Spindle-shaped cells with one nucleus and no visible striations.

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Skeletal vs. Smooth Muscle

Skeletal muscle has striations and multiple nuclei; smooth muscle lacks striations and has one nucleus.

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Excitability (Muscle)

The ability of muscle cells to respond to a stimulus.

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Contractility (Muscle)

The ability of muscle cells to shorten and generate a pulling force.

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Voluntary Muscle Movement

Muscle movement under conscious control.

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Involuntary Muscle Movement

Muscle movement not under conscious control.

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Skeletal Muscle

Attached to bones; responsible for locomotion and voluntary movements.

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Cardiomyocytes

Muscle cells that make up cardiac muscle.

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Oligodendrocyte

Produces myelin in the central nervous system (brain and spinal cord).

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Schwann Cell

Produces myelin in the peripheral nervous system.

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Myelin

A fatty substance that insulates nerve fibers.

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Central Nervous System (CNS)

The brain and spinal cord.

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Peripheral Nervous System (PNS)

Nerves outside the brain & spinal cord.

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Nervous Tissue Cell Types

Neuron (nerve cell) and Neuroglia (support cells).

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Neuron Parts

Cell body, dendrites, and axon.

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Synapse

Gap between nerve cells (or nerve and target) where neurotransmitters transmit signals.

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Neurotransmitters

Chemical compounds that transmit the impulse across the synapse.

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Neuron Stimulation

Action potential that propagates down the axon towards the synapse.

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Neuroglia Function

Support neurons and modulate their information propagation.

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Astrocyte Function

Regulate ions, uptake neurotransmitters, form blood-brain barrier.

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Carcinomas

Cancers originating from epithelial cells.

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Myelomas

Cancers arising from myeloid tissue or blood cells.

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Leukemias

Cancers of white blood cells.

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Sarcomas

Cancers derived from connective tissue.

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Cancer Stem Cells

A subtype of cell within a tumor responsible for uncontrolled growth.

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Inflammation

The body's initial response to injury, limiting damage and starting repair.

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Necrosis

Accidental cell death that causes inflammation.

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Apoptosis

Programmed cell death, a normal process that doesn't cause inflammation.

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Cardinal signs of inflammation

Redness, swelling, pain, and heat, indicating inflammation.

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Vasodilation

Widening of blood vessels, causing redness and heat during inflammation.

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Edema

Excess fluid in tissue, causing swelling during inflammation.

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-itis

The suffix meaning inflammation of a specific body part.

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NSAIDs

NSAIDs block prostaglandin synthesis, reducing pain.

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Antihistamines

Antihistamines block histamine receptors, alleviating allergy symptoms.

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Tissue Repair Start

Tissue repair begins with the removal of toxins and waste.

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Clotting (Coagulation)

Coagulation reduces blood loss by forming a fibrin network.

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Angiogenesis

Growth of new blood vessels in injured tissue.

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Primary Union

Primary union is wound healing with closely aligned edges.

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Secondary Union

Secondary union involves wound contraction to close gaping wounds.

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Regeneration

Adding new cells of the same type to replace injured ones.

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Senescence

Decline in body functions due to aging.

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Atrophy

Shrinking of tissue mass due to cell loss.

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Telomere Shortening

Telomeres shorten with each cell division, reducing cell regeneration.

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Cancer

Cells lose control of growth and invade other tissues.

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Mutation

Permanent change in a cell's DNA.

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Tumor

Mass of cells displaying abnormal architecture.

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Metastasis

Spread of cancer from its original site to other organs.

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Calcium Homeostasis

The maintenance of a stable level of calcium in the body.

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Skeletal System's Role

The skeletal system interacts with other organ systems to maintain calcium levels.

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Creative Commons

A license that allows sharing and modification with attribution.

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Calcium Regulation

The skeletal system participates in calcium homeostasis.

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Cell Differentiation

The process where a less specialized cell becomes more specialized.

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Embryonic Germ Layers

Cells in a developing embryo originate from these three primary germ layers.

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Mucosa

Epithelial tissue that lines body cavities exposed to the external environment.

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Simple Squamous Epithelium (Endothelium)

Epithelial tissue that lines the interior of blood vessels.

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Holocrine Gland

Gland that stores secretion until the cell ruptures.

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Connective Tissue Components

Essential components of connective tissue.

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Smooth Muscle

Muscle tissue found in the walls of internal organs; responsible for involuntary movements.

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Myoblasts

Cells that develop into muscle cells.

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Mitochondria

Organelles abundant in skeletal muscle cells to provide energy.

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Epithelial Tissue Function

Covers and lines surfaces for protection and secretion.

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Muscle Tissue Function

Specialized for contraction, enabling movement.

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Nervous Tissue Function

Transmits electrical signals for communication.

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Zygote Totipotency

The zygote can differentiate into any cell type.

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Mucosa Structure-Function

Facilitates nutrient absorption in the digestive system.

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Blood's Integrative Role

Transports nutrients, wastes, and immune cells.

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Neuron Adaptations

Transmits nerve impulses rapidly due to specific structures.

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Study Notes

  • Tissues are vulnerable to injury and aging.
  • Understanding tissue response to damage informs repair strategies.
  • Understanding aging's impact aids in diminishing its effects.
  • Inflammation represents the body's standard, initial response to injury, from biological to radiation burns.
  • Inflammation limits injury extent, eliminates its cause, and initiates tissue repair.
  • Necrosis, accidental cell death, causes inflammation.
  • Apoptosis is programmed cell death that doesn't initiate inflammation.
  • Acute inflammation resolves with tissue healing; chronic inflammation leads to disease.
  • "-itis" denotes inflammation of a specific organ (e.g., peritonitis, meningitis).
  • Four cardinal signs of inflammation include redness, swelling, pain, and local heat.
  • A fifth sign of inflammation may be loss of function.
  • Damaged cells release inflammatory signals that evoke local vasodilation.
  • Increased blood flow causes redness and heat.
  • Mast cells degranulate, releasing histamine, a potent vasodilator.
  • Increased blood flow and mediators attract white blood cells to the inflammation site.
  • Endothelium lining blood vessels becomes "leaky" due to histamine.
  • Neutrophils, macrophages, and fluid move into interstitial spaces causing edema (swelling).
  • Swollen tissues squeeze pain receptors causing the sensation of pain.
  • Prostaglandins released from injured cells activate pain neurons.
  • NSAIDs reduce pain by inhibiting prostaglandin synthesis.
  • NSAIDs like aspirin inhibit blood clot formation.
  • High levels of NSAIDs reduce inflammation.
  • Antihistamines decrease allergies by blocking histamine receptors.
  • Tissue repair starts with removing toxins and waste.
  • Clotting reduces blood loss and forms a fibrin network to trap cells and bind wound edges.
  • A scab forms when the clot dries, reducing infection risk.
  • Pus, a mixture of dead leukocytes and fluid, may accumulate in the wound.
  • Fibroblasts replace lost collagen and extracellular material.
  • Angiogenesis vascularizes new tissue, creating granulation tissue.
  • The clot retracts, pulling wound edges together and dissolving as tissue repairs.
  • Scarring occurs when a large amount of granulation tissue forms.
  • Primary union describes the healing of wounds with close edges.
  • Secondary union occurs in gaping wounds, with edges pulled together by wound contraction.
  • Sutures are recommended for wounds deeper than 1/4 inch to promote primary union and avoid scarring.
  • Regeneration is the addition of new cells of the same type that were injured.
  • Aging affects cells, tissues, and organs with individual variability.
  • Aging causes the skin to become thinner, drier, and less elastic, leading to wrinkles.
  • Hair turns gray due to less melanin production.
  • The face looks flabby due to decreased elastic and collagen fibers and muscle tone.
  • Height decreases as bones lose minerals.
  • Fluid decreases in vertebral cartilage disks with age.
  • Joints lose cartilage and stiffen.
  • Tissues, including muscles, lose mass through atrophy.
  • Passageways, blood vessels, and airways become more rigid.
  • The brain and spinal cord lose mass.
  • Nerves transmit impulses slower and less frequently.
  • Thought clarity and memory may decline.
  • Heart diseases, respiratory syndromes, and type 2 diabetes incidence increases with age.
  • Wound healing slows in the elderly with a higher infection risk.
  • Telomeres shorten with each cell division, reducing regeneration ability.
  • Oxygen and nutrient transport into cells and waste removal become less efficient.
  • Cells may function abnormally, leading to diseases like arthritis and some cancers.
  • Exercise and healthy lifestyle choices can slow down the body's deterioration with age.
  • Cancer involves cells escaping regulatory signals, leading to uncontrolled growth and invasion.
  • Tumors can "rob" blood supply from normal organs.
  • A mutation is a permanent change in a cell's DNA.
  • Epigenetic modifications alter DNA decoding, generating abnormal cells.
  • Alterations in genetic material may be caused by environmental or infectious agents, or errors in DNA replication.
  • Mutations can affect key proteins impacting the cell's ability to proliferate.
  • A tumor is a mass of cells displaying abnormal architecture.
  • Benign tumors do not metastasize or cause disease.
  • Malignant tumors breach tissue confines, promote angiogenesis, and metastasize.
  • Carcinomas derive from epithelial cells.
  • Myelomas form in myeloid tissue or blood cells.
  • Leukemias are cancers of white blood cells.
  • Sarcomas derive from connective tissue.
  • Cancer stem cells may be responsible for uncontrolled growth.
  • Tumors have structures, contrary to previous assumptions.
  • Cancer treatments include surgery, radiation, chemotherapy, and hormonal therapy.
  • New pharmaceuticals target specific proteins implicated in cancer pathways.
  • Calcium Homeostasis involves interactions of the skeletal system with other organ systems.
  • Embryonic is not a type of tissue.
  • Differentiation describes less specialized cells maturing into more specialized cells.
  • Differentiated cells in a developing embryo derive from the ectoderm, mesoderm, and endoderm.
  • Mucosa lines body cavities exposed to the external environment.
  • Columnar epithelial tissue has cells arranged in a single layer that look tall and narrow, with the nucleus located close to the basal side of the cell.
  • Simple squamous epithelial tissue lines the interior of blood vessels.
  • Pseudostratified ciliated columnar epithelium specializes in moving particles across its surface.
  • The holocrine exocrine gland stores its secretion until the glandular cell ruptures, whereas the apocrine gland releases its apical region and reforms.
  • Connective tissue is made of cells, ground substance, and protein fibers.
  • Hyaline cartilage is a tissue with cells located in spaces scattered in a transparent background when viewed under a microscope.
  • Adipose tissue specializes in the storage of fat.
  • Ligaments contain dense regular connective tissue.
  • In adults, new connective tissue cells originate from the mesenchyme.
  • In bone, the main cells are osteocytes.
  • Striations, cylindrical cells, and multiple nuclei are observed in skeletal and cardiac muscles.
  • Muscle cells (myocytes) develop from myoblasts.
  • Skeletal muscle cells contain abundant mitochondria.
  • Neurons are responsible for the transmission of the nerve impulse.
  • The nerve impulse travels down an axon away from the cell body.
  • Astrocytes regulate ions and the uptake/breakdown of some neurotransmitters, and contribute to the formation of the blood-brain barrier.
  • Fever is not a cardinal sign of inflammation.
  • When a mast cell reacts to irritation, it releases histamine.
  • Atrophy refers to loss of mass.
  • Genetic factors cannot be modified to slow the rate of aging.
  • It's important to monitor cuts and abrasions for increased redness, swelling, and pain to detect potential infections.
  • Regular use of anti-inflammatory drugs can have undesirable consequences due to suppression of the body's normal response to infection.
  • Steroids, such as cortisol that are used to treat autoimmune conditions, can also down-regulate the inflammatory response.
  • The four tissue types in the body are epithelial, connective, muscle, and nervous tissue, each with unique major functions.
  • Blood integrates organs and organ systems in the body through transport and regulation.
  • Hyaline cartilage heals slowly due to its avascular nature.
  • Spontaneously contracting cells in a dish that begin contracting in synchrony are likely cardiac muscle cells.
  • Morphological adaptations of neurons make them suitable for the transmission of nerve impulses.
  • Factors contributing to compromised functioning as an individual ages include the accumulation of cellular damage, such as shortening telomeres, and decreased efficiency of physiological processes which impairs tissue regeneration and repair.
  • The zygote’s totipotency gives rise to all cells including the highly specialized cells of the nervous system through differentiation.
  • The structure of the mucosa and its cells match its function of nutrient absorption.

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The human body is composed of diverse cell types organized into tissues. These cells, though sharing internal structures, vary significantly in shape and function. Beginning as a single cell, they divide and differentiate, committing to specific developmental pathways to form the complex tissues of the body.

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