Human Anatomy and Disease Overview
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Questions and Answers

What is the name of the disease if there is an excessive amount of growth in the area of the neck after a fall?

Basal/squamous cell carcinoma

What is the function of "protein located on chromosome 13"?

  • It regulates the cell cycle.
  • It releases a growth factor and allows G1 to S progression. (correct)
  • It is responsible for the production of hormones.
  • It prevents the development of cancer.

What is the name of the layer that gives rise to all tissues of the embryo?

Epiblast

What is the condition that causes the development of green penile discharge?

<p>Gonorrhoea</p> Signup and view all the answers

Match the following antibiotics with their respective mechanism of action:

<p>Vancomycin = Inhibits transpeptidase Aminoglycosides = Inhibits bacterial RNA polymerase Quinolone = Inhibits bacterial DNA gyrase (topoisomerase II) Macrolides = Binds 30s subunit Cephalosporin = Inhibits peptidoglycan polymerase</p> Signup and view all the answers

Which of the following options is NOT a possible cause of black stool?

<p>Myelodysplasia (C)</p> Signup and view all the answers

What is the name of the structure that equalizes atmospheric pressure in the middle ear?

<p>Eustachian Tube</p> Signup and view all the answers

A person with problems with the pulmonary bronchi issues has likely experienced an abnormal development in the endoderm layer during embryonic development.

<p>True (A)</p> Signup and view all the answers

Which specific nerve can be compressed or damaged by a bronchogenic cancer, leading to difficulty in speaking?

<p>Left recurrent laryngeal nerve</p> Signup and view all the answers

What is the pathogenesis of osteoporosis in post-menopausal women?

<p>Loss of estrogen levels in the absence of which osteoclast activity is unregulated, and bone degradation is dominant.</p> Signup and view all the answers

What is the name of the bacterial infection that causes the symptoms of pelvic pain, small amount of bleeding and discharge in women?

<p>Chlamydia</p> Signup and view all the answers

Flashcards

Encapsulated bacteria

Bacteria that have a polysaccharide capsule surrounding their cell wall, contributing to their virulence by helping them evade the host's immune system.

Lipopolysaccharide (LPS)

A major component of the outer membrane of Gram-negative bacteria, acting as an endotoxin, causing inflammation and potentially sepsis.

Chitin

A structural polysaccharide found in the exoskeletons of arthropods and cell walls of some fungi, providing rigidity and support.

Phospholipids in viral capsules

Viral capsules often use phospholipids from the host cell membrane during budding, making them more difficult for the immune system to recognize.

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Prions

Misfolded proteins that can cause fatal neurodegenerative diseases by converting normal proteins into abnormal forms.

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Cortisol's effect on bone

Cortisol, a steroid hormone, can contribute to bone damage by increasing osteoclast activity, leading to bone resorption (dissolving bone tissue).

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Calcitriol (Vitamin D3)

The active form of vitamin D, synthesized in the kidneys, plays a crucial role in calcium absorption and bone health by promoting osteoblast activity.

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Parathyroid hormone (PTH)

A hormone produced by the parathyroid glands, primarily regulating calcium levels by stimulating osteoclast activity and increasing calcium reabsorption by kidneys.

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Calcium and Vitamin D supplementation

Often recommended for individuals with osteoporosis to increase bone density, as they play essential roles in bone formation and maintenance.

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Estrogen's role in bone health

Estrogen, a sex hormone, helps maintain bone density by inhibiting osteoclast activity, explaining higher risk of osteoporosis in post-menopausal women.

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Carbamazepine's MOA in trigeminal neuralgia

Carbamazepine, an anticonvulsant medication, helps manage trigeminal neuralgia pain by blocking sodium channels in nerve fibers, reducing nerve impulses.

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Thumb abduction

Moving the thumb away from the palm of the hand, perpendicular to the other fingers.

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Median nerve injury

Damage to the median nerve can result in weakness or difficulty flexing the thumb, index and middle fingers, as well as impaired sensation in the palm and fingers.

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Palmar Interossei

Muscle group in the hand responsible for adduction (bringing fingers together) of the fingers.

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Dorsal Interossei

Muscle group in the hand responsible for abduction (spreading fingers apart) of the fingers.

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Stratum corneum

The outermost layer of the epidermis, consisting of dead, keratinized cells that protect the skin.

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Stratum basale

The deepest layer of the epidermis, containing stem cells that constantly divide to replenish the skin, as well as melanocytes and Merkel cells.

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Acantholysis

The breaking down of cell-to-cell adhesions (desmosomes) in the stratum spinosum, sometimes occurring during skin diseases.

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Langerhans cells

Specialized immune cells found in the stratum spinosum, responsible for antigen presentation to T cells, initiating immune responses.

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Papillary dermis

The upper layer of the dermis, containing capillaries and nerve endings, providing mechanical support and nourishment to the epidermis.

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Lesion after the internal acoustic meatus

A lesion in the facial nerve after the internal acoustic meatus can cause symptoms including loss of lacrimation, hyperacusis, loss of taste, and facial paralysis, without affecting other neurological functions.

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Lesion after the geniculate nucleus

A lesion in the facial nerve after the geniculate nucleus may lead to hyperacusis, metallic taste, and other symptoms, but not necessarily facial paralysis.

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Biased measurement

A measurement that consistently deviates from the true value due to systematic errors or influences.

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Repeatable measurement

A measurement that consistently produces the same outcome when repeated under the same conditions using the same method.

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Reproducible measurement

A measurement that consistently produces the same outcome when repeated under the same conditions, even if using different methods or performed by different individuals.

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Valid measurement

A measurement that truly captures the intended quantity or concept, being relevant and appropriate for the purpose.

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Bleeding gastric ulcer

A condition where a peptic ulcer in the stomach bleeds, often presenting with black stool (melena) and pain.

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Iron deficiency anemia

A type of anemia caused by insufficient iron levels in the body, leading to reduced hemoglobin production and symptoms like fatigue, pale skin, and koilonychias (spoon-shaped nails).

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Pernicious anemia

A type of anemia caused by inadequate absorption of vitamin B12 due to an autoimmune condition, resulting in megaloblastic anemia (large red blood cells) and neurological symptoms.

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Study Notes

Encapsulated Organisms

  • Listed encapsulated organisms include Hemophilus and Neisseria.
  • Outer membrane of Salmonella can cause diarrhea.
  • Arthropod exoskeletons exist.
  • Paramyxoviruses and orthomyxoviruses utilize host cell membranes to form capsules.
  • Creutzfeldt-Jacobs disease involves prions.
  • Cushing's syndrome can cause bone damage.

Hormone Synthesis and Regulation

  • Cortisol is synthesized in the kidney from a precursor.
  • 1,25-dihydroxycholecalciferol (Calcitriol) is involved.
  • Parathyroid hormone (PTH) is involved.
  • Osteoclasts are activated by PTH.
  • Calcium and Vitamin D are involved in bone health.
  • Estrogen is a factor.

Trigeminal Neuralgia Treatment

  • Carbamazepine is used to treat trigeminal neuralgia.
  • It works by affecting sodium channels.

Nerve Damage and Movements

  • Damage to the median nerve can affect finger movement.
  • Thumb abduction and adduction involve specific muscles.

Skin Layers

  • Stratum corneum is the outermost skin layer.
  • Stratum granulosum is another skin layer involved in keratinocyte function.
  • Stratum spinosum contains desmosomes that break during acantholysis.
  • Stratum basale is composed of various vital cells.

Facial Nerve Lesions

  • Lesions after the internal acoustic meatus and before the geniculate nuclei might cause specific neurological symptoms affecting taste, hearing etc.
  • Lesions after the geniculate nucleus can have hyperacusis and metallic taste symptoms.
  • Facial nerve lesions can cause issues with facial expression and muscle function.
  • Parotid gland tumors/lesions can also cause swelling and facial expression loss.

Measurement Validity and Reliability

  • Same measure, same outcome, same method is considered relevant, repeatable, and appropriate.
  • Methods using the same measure, same outcome, differing methods are also relevant and might also be repeatable.
  • Relevant and appropriate measures are also critical for valid measurements by users.

Other Medical Conditions and Treatments

  • Black stool and joint pain might indicate nonsteroidal anti-inflammatory drug (NSAID) use.
  • Koilonychias and tongue atrophy are possible conditions.
  • Treatment of small cell carcinoma involves chemotherapy.
  • Diabetic patients with renal impairment display fatigue and shortness of breath.
  • Chemical carcinogens cause cancer.
  • Prolonged or excessive bleeding at regular intervals, bleeding at irregular intervals, and increased bleeding are potential concerns.
  • Mutations in colon cancer can involve specific regulators during cell cycle.
  • Swelling and facial expression loss could be related to parotid gland tumor/lesion.
  • Low vegetable intake can lead to scurvy and tooth loss.
  • In reproductive health, progesterone release occurs during the secretory phase.
  • Reproductive hormones like LH, HCG, can stimulate or regulate different reproductive functions.
  • Treatments for infections and diseases involve various substances like antibiotics (cephalosporin, vancomycin, rifampicin, gentamicin, quinolone), anti-inflammatory drugs.
  • Prolonged bleeding can occur during different cycles (menorrhagia, metrorrhagia, polymenorrhea)
  • Disorders relating to the auditory system or face are potentially serious and should be treated with relevant medical/ surgical attention.
  • Aneurysm in the aorta could be a result of genetic disorders.
  • Muscle weakness can arise due to conditions like myasthenia gravis.
  • Severe disorders like facial nerve lesions or other neurological impairment warrant immediate attention and medical treatment.
  • Tumors and lesions located in different areas/structures of the body can have consequences based on their location and the nature of the tumor.
  • Different types of infections have varying symptoms in different people. Additional symptoms include skin conditions like blisters and cheesy vaginal discharge.

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Description

Explore various topics related to human anatomy and disease, including encapsulated organisms, hormone synthesis, and treatments for conditions like trigeminal neuralgia. This quiz also covers the effects of nerve damage and the structure of skin layers. Test your understanding of these key biological concepts!

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