How well do you know transcription factors and their role in gene regulation?
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Questions and Answers

What is the role of transcription factors?

  • They regulate transcription by binding to gene promoters. (correct)
  • They are responsible for DNA replication.
  • They facilitate protein-protein interactions between cells.
  • They are involved in protein synthesis.
  • True or false:There are more transcription factors in the human genome than there are genes.

    False

    True or false:Transcription factors regulate gene expression by binding to gene promoters.

    True

    True or false: There are approximately 23,000 transcription factors encoded in the human genome.

    <p>False</p> Signup and view all the answers

    How many transcription factors are there that regulate the genes encoded in the human genome?

    <p>About 3000</p> Signup and view all the answers

    True or false: Transactivation domains prevent transcription by RNA polymerase.

    <p>False</p> Signup and view all the answers

    True or false: Transcription factors contain only one type of protein domain.

    <p>False</p> Signup and view all the answers

    What are the four common types of DNA-binding domains found in transcription factors?

    <p>Helix-turn-helix, leucine zipper, helix-loop-helix, and zinc finger motifs.</p> Signup and view all the answers

    True or false: Dimerization domains are not involved in protein-protein interactions between transcription factors.

    <p>False</p> Signup and view all the answers

    What is the role of ligand-binding domains in transcription factors?

    <p>They are required for some transcription factors to function.</p> Signup and view all the answers

    True or false: Ligand-binding domains are not necessary for some transcription factors to work.

    <p>False</p> Signup and view all the answers

    True or false: Zinc finger motifs are not one of the four common types of DNA-binding domains.

    <p>False</p> Signup and view all the answers

    True or false: The activity of a transcription factor cannot be regulated by synthesis in particular cell types or covalent modification.

    <p>False</p> Signup and view all the answers

    How can the activity of a transcription factor be regulated?

    <p>By synthesis in particular cell types, covalent modification, etc</p> Signup and view all the answers

    True or false: Interactions between transcription factors are not important in transcriptional regulation.

    <p>False</p> Signup and view all the answers

    Study Notes

    • Transcription factors regulate transcription by binding to gene promoters.
    • There are about 3000 transcription factors that regulate the 23,000 genes encoded in the human genome.
    • Transcription factors contain different protein domains with specific roles.
    • The four common types of DNA-binding domains are helix-turn-helix, leucine zipper, helix-loop-helix, and zinc finger motifs.
    • The conformation of protein domains facilitates binding to DNA.
    • Transactivation domains induce transcription by RNA polymerase.
    • Dimerization domains facilitate protein-protein interactions between transcription factors.
    • Ligand-binding domains are required for some transcription factors to function.
    • The activity of a transcription factor can be regulated by synthesis in particular cell types, covalent modification, etc.
    • Interactions between transcription factors are a common theme in transcriptional regulation.

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    Description

    Test your knowledge on transcription factors and their role in regulating gene expression with this informative quiz! Learn about the different protein domains that make up transcription factors, how they bind to DNA, and the various ways in which their activity can be regulated. Challenge yourself with questions on the different types of DNA-binding domains, transactivation domains, dimerization domains, and ligand-binding domains. Discover how interactions between transcription factors play a crucial role in controlling transcriptional regulation. Put your skills to the test and see

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