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Questions and Answers
What is the purpose of autoregulation of GFR?
What is the purpose of autoregulation of GFR?
- To increase GFR in response to changes in blood pressure and flow.
- To decrease GFR in response to changes in blood pressure and flow.
- To maintain GFR despite changes in blood pressure and flow. (correct)
- To prevent blood from flowing into the glomerulus.
Which structures does the myogenic response affect?
Which structures does the myogenic response affect?
- Afferent arterioles only
- Efferent arterioles only
- Glomerular capillaries only
- Afferent arterioles, efferent arterioles, and glomerular capillaries (correct)
What happens when there is reduced blood flow in the kidney?
What happens when there is reduced blood flow in the kidney?
- Afferent arterioles and glomerular capillaries constrict, while efferent arterioles dilate
- Afferent arterioles and glomerular capillaries dilate, while efferent arterioles constrict. (correct)
- Afferent arterioles and efferent arterioles constrict, while glomerular capillaries dilate
- Afferent arterioles and efferent arterioles dilate, while glomerular capillaries constrict.
What happens when there is a rise in renal blood pressure?
What happens when there is a rise in renal blood pressure?
What is the tubuloglomerular feedback mechanism?
What is the tubuloglomerular feedback mechanism?
What do macula densa cells detect?
What do macula densa cells detect?
What do macula densa cells secrete in response to increased salt levels?
What do macula densa cells secrete in response to increased salt levels?
What is the effect of ATP and adenosine on the adjacent afferent arteriole?
What is the effect of ATP and adenosine on the adjacent afferent arteriole?
What is the purpose of constriction of the afferent arteriole?
What is the purpose of constriction of the afferent arteriole?
What is the purpose of constriction of the efferent arteriole?
What is the purpose of constriction of the efferent arteriole?
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Study Notes
- Autoregulation of GFR maintains GFR despite changes in local blood pressure and flow.
- Myogenic response changes the diameters of afferent arterioles, efferent arterioles, and glomerular capillaries.
- Reduced blood flow triggers dilation of afferent arteriole and glomerular capillaries and constriction of efferent arterioles.
- Rise in renal blood pressure constricts afferent arterioles and decreases glomerular blood flow.
- Tubuloglomerular feedback mechanism involves tubular and vascular cells of the juxtaglomerular apparatus.
- Macula densa cells detect changes in salt level of the fluid flowing past.
- Increased salt causes macula densa to secrete ATP and adenosine.
- ATP and adenosine cause smooth muscles of adjacent afferent arteriole to constrict.
- Constriction reduces blood flow into the glomerulus.
- Constriction reduces GFR.
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