How well do you know the oxidative decarboxylation process?
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Questions and Answers

What is the rate-limiting step in the TCA cycle?

  • Oxidative decarboxylation by α-KGDH
  • Oxidative decarboxylation by IDH (correct)
  • Entry of intermediates into the TCA cycle
  • Synthesis of porphyrin

Which of the following are IDH (+) activators?

  • ATP and NADH
  • NAD+ and NADP+
  • ADP and Ca2+ (correct)
  • NAD+ and Ca2+

What are the IDH (-) inhibitors?

  • NAD+ and Ca2+
  • ATP and NADH (correct)
  • NAD+ and NADP+
  • ADP and Ca2+

Which enzyme carries out the 2nd oxidative decarboxylation in the TCA cycle?

<p>α-Ketoglutarate dehydrogenase (α-KGDH) (A)</p> Signup and view all the answers

What is the metabolic branch point in which intermediates enter or exit the TCA cycle?

<p>Succinyl CoA (C)</p> Signup and view all the answers

What is the starting point for the synthesis of heme?

<p>Succinyl CoA (C)</p> Signup and view all the answers

How many IDH enzymes are there in the TCA cycle?

<p>Two (A)</p> Signup and view all the answers

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