How well do you know gluconeogenesis?
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Questions and Answers

Which enzyme catalyzes the conversion of fructose-1,6-bisphosphate to fructose-6-phosphate in gluconeogenesis?

  • Pyruvate carboxylase
  • Phosphoenolpyruvate carboxykinase
  • Glucose-6-phosphatase
  • Fructose-1,6-bisphosphatase (correct)

    • Which molecule is produced by the decarboxylation of oxaloacetate in gluconeogenesis?

  • Fructose-6-phosphate
  • Pyruvate
  • Oxaloacetate
  • Phosphoenolpyruvate (correct)

    • Which reaction in gluconeogenesis is a major point of control, similar to the regulation of glycolysis at the PFK-1 reaction?

  • Conversion of fructose-1,6-bisphosphate to fructose-6-phosphate (correct)
  • Conversion of fructose-6-phosphate to fructose-1,6-bisphosphate
  • Conversion of glucose-6-phosphate to glucose
  • Conversion of pyruvate to oxaloacetate

    • Which molecule is used to enable phosphorylation during the decarboxylation of oxaloacetate in gluconeogenesis?

    <p>GTP (D)</p> Signup and view all the answers

    Which enzyme catalyzes the conversion of pyruvate to oxaloacetate in gluconeogenesis?

    <p>Pyruvate carboxylase (B)</p> Signup and view all the answers

    Which molecule is produced by the reaction catalyzed by phosphoenolpyruvate carboxykinase (PEPCK) in gluconeogenesis?

    <p>Phosphoenolpyruvate (B)</p> Signup and view all the answers

    Which molecule is converted to fructose-1,6-bisphosphate in glycolysis?

    <p>Fructose-6-phosphate (A)</p> Signup and view all the answers

    Which enzyme catalyzes the conversion of glucose-6-phosphate to glucose in gluconeogenesis?

    <p>Glucose-6-phosphatase (C)</p> Signup and view all the answers

    Which molecule is produced by the reaction catalyzed by pyruvate carboxylase in gluconeogenesis?

    <p>Oxaloacetate (C)</p> Signup and view all the answers

    Which molecule is converted to fructose-6-phosphate in glycolysis?

    <p>Glyceraldehyde-3-phosphate (C)</p> Signup and view all the answers

    Which enzyme catalyzes the conversion of fructose-1,6-bisphosphate to fructose-6-phosphate in gluconeogenesis?

    <p>Fructose-1,6-bisphosphatase (B)</p> Signup and view all the answers

    Which molecule is produced by the decarboxylation of oxaloacetate in gluconeogenesis?

    <p>Phosphoenolpyruvate (A)</p> Signup and view all the answers

    Which reaction in gluconeogenesis is a major point of control, similar to the regulation of glycolysis at the PFK-1 reaction?

    <p>Conversion of fructose-1,6-bisphosphate to fructose-6-phosphate (C)</p> Signup and view all the answers

    Which molecule is used to enable phosphorylation during the decarboxylation of oxaloacetate in gluconeogenesis?

    <p>GTP (C)</p> Signup and view all the answers

    Which enzyme catalyzes the conversion of pyruvate to oxaloacetate in gluconeogenesis?

    <p>Pyruvate carboxylase (C)</p> Signup and view all the answers

    Which molecule is produced by the reaction catalyzed by phosphoenolpyruvate carboxykinase (PEPCK) in gluconeogenesis?

    <p>Phosphoenolpyruvate (B)</p> Signup and view all the answers

    Which molecule is converted to fructose-1,6-bisphosphate in glycolysis?

    <p>Fructose-6-phosphate (B)</p> Signup and view all the answers

    Which enzyme catalyzes the conversion of glucose-6-phosphate to glucose in gluconeogenesis?

    <p>Glucose-6-phosphatase (D)</p> Signup and view all the answers

    Which molecule is produced by the reaction catalyzed by pyruvate carboxylase in gluconeogenesis?

    <p>Oxaloacetate (A)</p> Signup and view all the answers

    Which molecule is converted to fructose-6-phosphate in glycolysis?

    <p>Glyceraldehyde-3-phosphate (A)</p> Signup and view all the answers

    Which enzyme catalyzes the conversion of fructose-1,6-bisphosphate to fructose-6-phosphate in gluconeogenesis?

    <p>Fructose-1,6-bisphosphatase (C)</p> Signup and view all the answers

    What is the product of oxaloacetate decarboxylation in gluconeogenesis?

    <p>PEP (A)</p> Signup and view all the answers

    Which reaction in gluconeogenesis is a major point of control, similar to the regulation of glycolysis at the PFK-1 reaction?

    <p>Fructose-1,6-bisphosphate conversion to fructose-6-phosphate (C)</p> Signup and view all the answers

    What is the enzyme responsible for catalyzing the reaction that releases the energy needed to enable phosphorylation by GTP in gluconeogenesis?

    <p>Phosphoenolpyruvate carboxykinase (B)</p> Signup and view all the answers

    What is the end product of gluconeogenesis?

    <p>Glucose-6-phosphate (D)</p> Signup and view all the answers

    Which molecule is converted to phosphoenolpyruvate in gluconeogenesis?

    <p>Fructose-1,6-bisphosphate (B)</p> Signup and view all the answers

    Which enzyme catalyzes the conversion of fructose-6-phosphate to glucose-6-phosphate in gluconeogenesis?

    <p>Glucose-6-phosphatase (B)</p> Signup and view all the answers

    What is the role of GTP in gluconeogenesis?

    <p>To release energy needed for phosphorylation (B)</p> Signup and view all the answers

    Which molecule is converted to fructose-6-phosphate by fructose-1,6-bisphosphatase in gluconeogenesis?

    <p>Fructose-1,6-bisphosphate (B)</p> Signup and view all the answers

    Which enzyme catalyzes the conversion of pyruvate to oxaloacetate in gluconeogenesis?

    <p>Phosphoenolpyruvate carboxykinase (D)</p> Signup and view all the answers

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