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How Well Do You Know DNA Replication and Mismatch Repair?

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How Well Do You Know DNA Replication and Mismatch Repair?

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Questions and Answers

What is the main function of DNA polymerase III during replication?

To replace mismatched nucleotides

To fill gaps in the newly synthesized DNA

To remove RNA primers

To synthesize Okazaki fragments (correct)

What happens when a nucleotide mismatch occurs during replication?

Gaps are filled with DNA

DNA polymerase III continues synthesis

DNA polymerase III removes the mismatched nucleotide (correct)

RNA primers are removed

What is the role of the 3'→5' exonuclease activity of DNA polymerase III?

To fill gaps in the newly synthesized DNA

To synthesize Okazaki fragments

To remove mismatched nucleotides (correct)

To remove RNA primers

What happens after DNA polymerase III removes a mismatched nucleotide?

DNA polymerase III resumes synthesis Signup and view all the answers

What is the function of DNA polymerase I during replication?

To fill gaps in the newly synthesized DNA Signup and view all the answers

What happens if RNA primers are not removed from the newly synthesized DNA?

Gaps will be created in the DNA Signup and view all the answers

How many gaps are created in the newly synthesized DNA in the lagging strand during replication?

Multiple Signup and view all the answers

What is the role of primase during replication?

To synthesize RNA primers Signup and view all the answers

Why are RNA primers removed from the newly synthesized DNA during replication?

Because RNA primers cannot remain in the DNA Signup and view all the answers

What is the function of DNA polymerase III during replication in the leading strand?

To synthesize continuous complementary DNA Signup and view all the answers